PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_576_f_7
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family ERF
Protein Properties Length: 291aa    MW: 32403.5 Da    PI: 6.0924
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_576_f_7genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP262.49.8e-2079128255
           AP2   2 gykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 
                   +y+GVr+++ +g+W+AeIrdp+    + +r++lg+f tae Aa+a++aa++k++g
  Neem_576_f_7  79 HYRGVRQRP-WGKWAAEIRDPK----KaARVWLGTFETAEAAAAAYDAAALKFKG 128
                   7********.**********94....45************************987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.7E-3278137IPR001471AP2/ERF domain
SMARTSM003801.5E-3679142IPR001471AP2/ERF domain
PROSITE profilePS5103225.19879136IPR001471AP2/ERF domain
PfamPF008475.3E-1379128IPR001471AP2/ERF domain
CDDcd000183.38E-2279137No hitNo description
SuperFamilySSF541714.71E-2279137IPR016177DNA-binding domain
PRINTSPR003672.3E-118091IPR001471AP2/ERF domain
PRINTSPR003672.3E-11102118IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009414Biological Processresponse to water deprivation
GO:0009651Biological Processresponse to salt stress
GO:0009723Biological Processresponse to ethylene
GO:0009737Biological Processresponse to abscisic acid
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071497Biological Processcellular response to freezing
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 291 aa     Download sequence    Send to blast
MQFTCLILWE IDRHGKRPLP FDASEEKKED EVIFPDPRQD QRSSASAATS GDHRQPHGQG  60
GQDTSSQPTQ DQGNIRRRHY RGVRQRPWGK WAAEIRDPKK AARVWLGTFE TAEAAAAAYD  120
AAALKFKGSK AKLNFPERVT GADSGFFLSS ASNPGTVSLP QHFPISNIPP PQTLPYPLSH  180
HPINPSSTLS YDQMFPNLFQ YAQLLSSNDD NNFQYAAPNL YNYSQDQPFH SQSSSIIFST  240
PTMSSAMSQN QNPLENDMFS FSSCSRMGSF SSASDSVEQE KDSLDDGNQK E
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A9e-2678139163ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A1e-2578143470ATERF1
3gcc_A1e-2578143470ATERF1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator involved in the regulation of plant development and tolerance to abiotic stresses (PubMed:21069430). Acts as positive regulator of tolerance to waterlogging stress. Delays waterlogging-induced premature senescence by regulating stomatal closure and antioxidant enzyme activity. May function through ABI1-mediated abscisic acid (ABA) signaling pathway (PubMed:22661072). Involved in tissue reunion of wounded inflorescence stems. Required for the division of pith cells in the reunion process, which is dependent on polar-transported auxin and the wound-inducible hormones ethylene and jasmonate (PubMed:21911380). Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:21911380, ECO:0000269|PubMed:22661072}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by salt stress (PubMed:16133218, PubMed:21069430). Induced drought stress, jasmonate (JA), salicylic acid (SA), abscisic acid (ABA) and ethylene. Down-regulated by freezing stress (PubMed:21069430). Induced by wounding in the flowering stem (PubMed:21911380). Induced by waterlogging. {ECO:0000269|PubMed:16133218, ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:21911380}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024046519.11e-63ethylene-responsive transcription factor ERF114
SwissprotQ9LYU33e-43EF113_ARATH; Ethylene-responsive transcription factor ERF113
TrEMBLA0A2H5Q4J12e-63A0A2H5Q4J1_CITUN; Uncharacterized protein
STRINGXP_006469112.14e-63(Citrus sinensis)
STRINGXP_006446923.15e-63(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G07310.12e-39ERF family protein
Publications ? help Back to Top
  1. Huang Z,Zhao P,Medina J,Meilan R,Woeste K
    Roles of JnRAP2.6-like from the transition zone of black walnut in hormone signaling.
    PLoS ONE, 2013. 8(11): p. e75857
    [PMID:24265672]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Asahina M,Satoh S
    Molecular and physiological mechanisms regulating tissue reunion in incised plant tissues.
    J. Plant Res., 2015. 128(3): p. 381-8
    [PMID:25736731]
  4. Hickman R, et al.
    Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network.
    Plant Cell, 2017. 29(9): p. 2086-2105
    [PMID:28827376]
  5. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  6. Matsuoka K, et al.
    RAP2.6L and jasmonic acid-responsive genes are expressed upon Arabidopsis hypocotyl grafting but are not needed for cell proliferation related to healing.
    Plant Mol. Biol., 2018. 96(6): p. 531-542
    [PMID:29344830]
  7. Yang S,Poretska O,Sieberer T
    ALTERED MERISTEM PROGRAM1 Restricts Shoot Meristem Proliferation and Regeneration by Limiting HD-ZIP III-Mediated Expression of RAP2.6L.
    Plant Physiol., 2018. 177(4): p. 1580-1594
    [PMID:29884678]