PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_3950_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family NAC
Protein Properties Length: 312aa    MW: 35946.4 Da    PI: 7.9164
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_3950_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM174.14.1e-5491381128
            NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvka.eekewyfFskrdkkyatgkrknratksgyWkatgkdkevl 93 
                    +ppGfrFhPtdeel+ +yL+kkv+ + ++l +vi+evd++k+ePwdL+ k ++ +  ++ewyfFs++dkky+tg+r+nrat++g+Wkatg+dk+++
  Neem_3950_f_1   9 VPPGFRFHPTDEELLYYYLRKKVSYEAIDL-DVIREVDLNKLEPWDLKdKcRIGSgPQNEWYFFSHKDKKYPTGTRTNRATTAGFWKATGRDKAIH 103
                    69****************************.9***************943444443456************************************* PP

            NAM  94 skkgelvglkktLvfykgrapkgektdWvmheyrl 128
                     ++++ +g++ktLvfy+grap+g+ktdW+mheyrl
  Neem_3950_f_1 104 LSNSKRIGMRKTLVFYTGRAPHGQKTDWIMHEYRL 138
                    *********************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019416.54E-605158IPR003441NAC domain
PROSITE profilePS5100558.2889158IPR003441NAC domain
PfamPF023653.2E-2810138IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003002Biological Processregionalization
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009834Biological Processplant-type secondary cell wall biogenesis
GO:0010455Biological Processpositive regulation of cell fate commitment
GO:0048829Biological Processroot cap development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 312 aa     Download sequence    Send to blast
MAGNGQLSVP PGFRFHPTDE ELLYYYLRKK VSYEAIDLDV IREVDLNKLE PWDLKDKCRI  60
GSGPQNEWYF FSHKDKKYPT GTRTNRATTA GFWKATGRDK AIHLSNSKRI GMRKTLVFYT  120
GRAPHGQKTD WIMHEYRLDD DNSEVQEDGW VVCRVFKKKN HNRCFQPEVS HQEEHFSYMK  180
ASASAPLEPK QSHMQALYDY TFDGSMHLPQ LFSPESAATP SFVSPISLNN MDIECSQNLL  240
RLTSSSSRLM QHERFSGDWS FLDKLLASHQ SLDHNLQNKC NASSQVIDVG TSSQKFPFHY  300
LGCESDLLKF AK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-52616014167NO APICAL MERISTEM PROTEIN
1ut4_B1e-52616014167NO APICAL MERISTEM PROTEIN
1ut7_A1e-52616014167NO APICAL MERISTEM PROTEIN
1ut7_B1e-52616014167NO APICAL MERISTEM PROTEIN
3swm_A1e-52616017170NAC domain-containing protein 19
3swm_B1e-52616017170NAC domain-containing protein 19
3swm_C1e-52616017170NAC domain-containing protein 19
3swm_D1e-52616017170NAC domain-containing protein 19
3swp_A1e-52616017170NAC domain-containing protein 19
3swp_B1e-52616017170NAC domain-containing protein 19
3swp_C1e-52616017170NAC domain-containing protein 19
3swp_D1e-52616017170NAC domain-containing protein 19
4dul_A1e-52616014167NAC domain-containing protein 19
4dul_B1e-52616014167NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269|PubMed:19081078, ECO:0000269|PubMed:20197506}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00250DAPTransfer from AT1G79580Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269|PubMed:19081078}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKR6051893e-87KR605189.1 Manihot esculenta NAC transcription factors 51 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002521498.10.0protein SOMBRERO isoform X2
SwissprotQ9MA171e-129SMB_ARATH; Protein SOMBRERO
TrEMBLB9S6790.0B9S679_RICCO; NAC domain-containing protein, putative
STRINGXP_002521498.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM66532542
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G79580.31e-116NAC family protein
Publications ? help Back to Top
  1. Fendrych M, et al.
    Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis.
    Curr. Biol., 2014. 24(9): p. 931-40
    [PMID:24726156]
  2. Bennett T,van den Toorn A,Willemsen V,Scheres B
    Precise control of plant stem cell activity through parallel regulatory inputs.
    Development, 2014. 141(21): p. 4055-64
    [PMID:25256342]
  3. Karve R,Suárez-Román F,Iyer-Pascuzzi AS
    The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release.
    Plant Physiol., 2016. 171(3): p. 2101-11
    [PMID:27221617]
  4. Kamiya M, et al.
    Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis.
    Development, 2016. 143(21): p. 4063-4072
    [PMID:27803060]