PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_34950_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

NAC

Protein Properties

Length: 335aa MW: 37650.2 Da PI: 8.5523

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_34950_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	167.3	5.2e-52	14	139	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlsk 95 lppGfrF Ptdeel+v+yL++kv+g++++l ++i e+d+yk++Pw Lp+k+ +ekewyfFs+rd+ky++g+r+nr++ sgyWkatg+dk +++ Neem_34950_f_1 14 LPPGFRFYPTDEELLVQYLCRKVAGHHFSL-QIIGEIDLYKFDPWVLPSKAIFGEKEWYFFSPRDRKYPNGSRPNRVAGSGYWKATGTDKVITT- 106 79*************************9.89***********7777799*********************************99. PP NAM 96 kgelvglkktLvfykgrapkgektdWvmheyrl 128 +g++vg+kk Lvfy g+apkg+kt+W+mheyrl Neem_34950_f_1 107 EGRKVGIKKALVFYVGKAPKGTKTNWIMHEYRL 139 999**************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	9.29E-67	10	163	IPR003441	NAC domain
PROSITE profile	PS51005	60.215	14	162	IPR003441	NAC domain
Pfam	PF02365	2.9E-26	15	139	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009414	Biological Process	response to water deprivation
GO:0009737	Biological Process	response to abscisic acid
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 335 aa Download sequence Send to blast
MGVPETDPLS QLNLPPGFRF YPTDEELLVQ YLCRKVAGHH FSLQIIGEID LYKFDPWVLP 60 SKAIFGEKEW YFFSPRDRKY PNGSRPNRVA GSGYWKATGT DKVITTEGRK VGIKKALVFY 120 VGKAPKGTKT NWIMHEYRLL ENSRKNGSSK LDDWVLCRIY KKNSSSQKPM STVSVSSKEH 180 SNGSCSSSSS HLDDVLESLP EIDVFALPRM NSLKTSQQLD EKINFQNLGS GNFDWASLAG 240 LNSVPELVSG GQTQSQGLPS YTNNDVYVPS IPQICQVDSG RVEEEVQSGL RSQRVDNTGF 300 FHQNSGMMNQ HNFSNPVDPY GFRYPTQPNG FGFRH

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	1e-111	1	168	7	174	NAC domain-containing protein 19
3swm_B	1e-111	1	168	7	174	NAC domain-containing protein 19
3swm_C	1e-111	1	168	7	174	NAC domain-containing protein 19
3swm_D	1e-111	1	168	7	174	NAC domain-containing protein 19
3swp_A	1e-111	1	168	7	174	NAC domain-containing protein 19
3swp_B	1e-111	1	168	7	174	NAC domain-containing protein 19
3swp_C	1e-111	1	168	7	174	NAC domain-containing protein 19
3swp_D	1e-111	1	168	7	174	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts downstream of MYC2 in the jasmonate-mediated response to Botrytis cinerea infection (PubMed:28733419). With MYC2 forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). Involved in jasmonate- and coronatine-mediated stomatal reopening in response to Pseudomonas syringae pv tomato DC3000 infection (PubMed:25005917). Regulates the expression of threonine deaminase 2 (TD2) through promoter binding (PubMed:28733419). {ECO:0000269\|PubMed:25005917, ECO:0000269\|PubMed:28733419}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by jasmonate (JA) (PubMed:25005917, PubMed:28733419, PubMed:30610166). Induced by wounding (PubMed:28733419, PubMed:25005917). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced by coronatine (PubMed:25005917). {ECO:0000269\|PubMed:25005917, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:30610166}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006464708.1	0.0	NAC domain-containing protein 72
Swissprot	A0A3Q7HH64	1e-148	JA2L_SOLLC; NAC domain-containing protein JA2L
TrEMBL	A0A067G6D8	0.0	A0A067G6D8_CITSI; Uncharacterized protein
TrEMBL	A0A2H5Q4H2	0.0	A0A2H5Q4H2_CITUN; Uncharacterized protein
STRING	XP_006464708.1	0.0	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1435	27	95

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G27410.2	1e-131	NAC family protein

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419] Liu Y, et al. MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop. Plant Cell, 2019. 31(1): p. 106-127 [PMID:30610166]