PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_29936_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family MYB
Protein Properties Length: 591aa    MW: 65289.2 Da    PI: 4.8638
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_29936_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding60.34.2e-193783148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g WT+eEde+l +av+++ g++Wk+Ia+++   Rt+ qc +rwqk+l
   Neem_29936_f_1 37 KGQWTPEEDEILRKAVQRFKGKNWKKIAECFK-DRTDVQCLHRWQKVL 83
                     799****************************9.************986 PP
2Myb_DNA-binding66.83.9e-2189135148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+W++eEde+++++v+++G++ W+tIa++++ gR +kqc++rw+++l
   Neem_29936_f_1  89 KGPWSKEEDEIIIELVNKYGPKKWSTIAQHLP-GRIGKQCRERWHNHL 135
                      79******************************.*************97 PP
3Myb_DNA-binding49.59.5e-16141183145
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 
                      + +WT+eE++ l++a++ +G++ W+   + ++ gRt++ +k++w+
   Neem_29936_f_1 141 KEAWTQEEELALIRAHQIYGNR-WAELTKFLP-GRTDNAIKNHWN 183
                      579*******************.*********.***********8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129418.4713283IPR017930Myb domain
SuperFamilySSF466893.24E-163389IPR009057Homeodomain-like
SMARTSM007171.0E-153685IPR001005SANT/Myb domain
PfamPF002491.1E-163783IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.609.2E-233890IPR009057Homeodomain-like
CDDcd001678.30E-154083No hitNo description
PROSITE profilePS5129433.52184139IPR017930Myb domain
SuperFamilySSF466893.95E-3286182IPR009057Homeodomain-like
SMARTSM007176.5E-2088137IPR001005SANT/Myb domain
PfamPF002491.4E-1989135IPR001005SANT/Myb domain
CDDcd001677.00E-1891135No hitNo description
Gene3DG3DSA:1.10.10.608.1E-2991138IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.3E-21139190IPR009057Homeodomain-like
SMARTSM007172.2E-15140188IPR001005SANT/Myb domain
PROSITE profilePS5129419.563140190IPR017930Myb domain
PfamPF002499.0E-14141184IPR001005SANT/Myb domain
CDDcd001672.03E-12143183No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 591 aa     Download sequence    Send to blast
MESDRVISTP SDGLSDGGQR MRPLHGRTSG PTRRSTKGQW TPEEDEILRK AVQRFKGKNW  60
KKIAECFKDR TDVQCLHRWQ KVLNPELVKG PWSKEEDEII IELVNKYGPK KWSTIAQHLP  120
GRIGKQCRER WHNHLNPAIN KEAWTQEEEL ALIRAHQIYG NRWAELTKFL PGRTDNAIKN  180
HWNSSVKKKL DSYLASGLLE QFQGLPLVGH QNQPMPSSSS RVQSSGDESA AKGAAEAEEI  240
SECSQDSAVV GHSHSAGNAV LHTREQFILT DESQQGKDQS SSPASCSEQY YTSLEDVTFT  300
IPEIPCEVDC SSKFPEQNFA HDAGTFANRD YQFNLQDLAN LSSIELGHQS SGLSAHCINS  360
HESQELVNVP FQSSVGLSVP SSIGNPAAGS AKPEHMLISD EECCRVLFVE AMKDGCFSLE  420
NFTQGLNMID SSLCRSLDIQ ISERDTTSSA QTYCPSKPEV LGTSCSQSFL SPPTLFSGDD  480
GALVYGKESS QINCQSYVTQ EQEFNTSGHD GFIYTNESAN SPCDNGTDNT SLQEPSYLAK  540
DSFKLVPVNS FGSESDVVIP CSSVDVKPEA QTEQEDAGAL CYEPPRFPTR I
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C1e-72371906159MYB PROTO-ONCOGENE PROTEIN
1h89_C1e-72371906159MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Transcription activator involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:26069325}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Constant levels during cell cycle. Activated by CYCB1. {ECO:0000269|PubMed:17287251}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006450634.10.0transcription factor MYB3R-1 isoform X1
RefseqXP_024034229.10.0transcription factor MYB3R-1 isoform X1
RefseqXP_024034230.10.0transcription factor MYB3R-1 isoform X2
RefseqXP_024034231.10.0transcription factor MYB3R-1 isoform X3
SwissprotQ9S7G71e-172MB3R1_ARATH; Transcription factor MYB3R-1
TrEMBLA0A2H5P7B10.0A0A2H5P7B1_CITUN; Uncharacterized protein
TrEMBLV4WBV50.0V4WBV5_9ROSI; Uncharacterized protein
STRINGXP_006450634.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM46742649
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32730.11e-163Homeodomain-like protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]