PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_27542_f_3
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family MYB
Protein Properties Length: 190aa    MW: 21855.8 Da    PI: 7.9199
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_27542_f_3genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding57.53.1e-185298148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     +g WT+eEd++l  av+++G ++Wk Ia++++  Rt  qc +rwqk+l
   Neem_27542_f_3 52 KGGWTEEEDKILEFAVEKFGARNWKNIAECVP-DRTSVQCLHRWQKVL 98
                     688*****************************.************986 PP
2Myb_DNA-binding62.39.8e-20104150148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      +g+WT+eEd+l++++v + G++ W+ Ia++++ gR +kqc++rw+++l
   Neem_27542_f_3 104 KGPWTKEEDDLIIELVGKQGNKKWSEIAKHLP-GRIGKQCRERWHNHL 150
                      79******************************.*************97 PP
3Myb_DNA-binding37.55.4e-12157188235
                      SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS CS
  Myb_DNA-binding   2 grWTteEdellvdavkqlGggtWktIartmgkgR 35 
                       +WT+eE++ l++a++ +G++ W+ Ia+ ++ gR
   Neem_27542_f_3 157 TAWTKEEELTLIKAHEIYGNK-WAEIAKLLP-GR 188
                      68*******************.*********.98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.3444798IPR017930Myb domain
SMARTSM007171.1E-1551100IPR001005SANT/Myb domain
PfamPF002491.1E-165298IPR001005SANT/Myb domain
SuperFamilySSF466891.09E-1753108IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.1E-2254106IPR009057Homeodomain-like
CDDcd001671.64E-135598No hitNo description
PROSITE profilePS5129431.68899154IPR017930Myb domain
SuperFamilySSF466898.99E-28101188IPR009057Homeodomain-like
SMARTSM007176.8E-18103152IPR001005SANT/Myb domain
CDDcd001671.60E-14106150No hitNo description
PfamPF139217.0E-20107165No hitNo description
Gene3DG3DSA:1.10.10.607.6E-28107153IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.607.2E-16154188IPR009057Homeodomain-like
PROSITE profilePS5129414.477155190IPR017930Myb domain
SMARTSM007170.0087155188IPR001005SANT/Myb domain
CDDcd001672.62E-7158188No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 190 aa     Download sequence    Send to blast
MVEATTCHND ENNEEGLVSL IPSVSDVSSH KAEAKRDYIQ GRMTGPTRRS TKGGWTEEED  60
KILEFAVEKF GARNWKNIAE CVPDRTSVQC LHRWQKVLDP SLVKGPWTKE EDDLIIELVG  120
KQGNKKWSEI AKHLPGRIGK QCRERWHNHL NPDIKKTAWT KEEELTLIKA HEIYGNKWAE  180
IAKLLPGRYC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h88_C1e-60521886142MYB PROTO-ONCOGENE PROTEIN
1h89_C1e-60521886142MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Transcription activator involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669). Transcription repressor that regulates organ growth. Binds to the promoters of G2/M-specific genes and to E2F target genes to prevent their expression in post-mitotic cells and to restrict the time window of their expression in proliferating cells (PubMed:26069325). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269|PubMed:17287251, ECO:0000269|PubMed:21862669, ECO:0000269|PubMed:26069325}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Constant levels during cell cycle. Activated by CYCB1. {ECO:0000269|PubMed:17287251}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021817082.16e-95uncharacterized protein LOC110759336
SwissprotQ9S7G78e-76MB3R1_ARATH; Transcription factor MYB3R-1
TrEMBLA0A2C9VV925e-93A0A2C9VV92_MANES; Uncharacterized protein
TrEMBLM5XNR52e-92M5XNR5_PRUPE; Uncharacterized protein
STRINGXP_008232807.11e-93(Prunus mume)
STRINGcassava4.1_033700m8e-94(Manihot esculenta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16672887
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G32730.13e-78Homeodomain-like protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]