PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_24188_f_1

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

bHLH

Protein Properties

Length: 259aa MW: 28876.3 Da PI: 9.9158

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_24188_f_1	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	26	1.6e-08	167	207	9	54
HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r RR+ri +++ L++l+P +K++ a++L +A++Y+k L Neem_24188_f_1 167 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 207 699***************87.....8**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.434	158	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	4.2E-14	159	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.44E-14	162	217	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	7.0E-14	164	213	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	7.6E-6	168	207	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	2.31E-6	181	212	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010500	Biological Process	transmitting tissue development
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0048462	Biological Process	carpel formation
GO:2000012	Biological Process	regulation of auxin polar transport
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 259 aa Download sequence Send to blast
MDVDMIKASQ EDHMDMMAAI MQMEKLPEFC EPFINSTPTL PEIQFSNGNT NSNITTQPIY 60 HNPSVSPPPT FGNSSSSTPF LNTPVQEPMT PPLQSNVVTG RFKSTSFALP NANPYPPTLE 120 KRNSMAAMRE MIFRVAAMQP IHIDPESIKP PKRRNVKISK DPQSVAARHR RERISERIRI 180 LQRLVPGGTK MDTASMLDEA IHYVKFLKKQ VQTLEQAGAH RPMAGVGFSG AGLANVGYPS 240 LIKACQQPSQ MVDNMHMFR

Functional Description ? help Back to Top
Source	Description
UniProt	Required for the female reproductive tract development and fertility. {ECO:0000269\|PubMed:17855426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269\|PubMed:17855426}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006425907.1	1e-129	transcription factor HEC2
Swissprot	Q9FHA7	9e-48	HEC1_ARATH; Transcription factor HEC1
TrEMBL	A0A067GKM3	1e-128	A0A067GKM3_CITSI; Uncharacterized protein
STRING	XP_006425907.1	1e-128	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1559	27	91

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G67060.1	3e-44	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Vercruyssen L, et al. ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell, 2014. 26(1): p. 210-29 [PMID:24443518] Sparks EE,Benfey PN HEC of a job regulating stem cells. Dev. Cell, 2014. 28(4): p. 349-50 [PMID:24576420] Zhu L, et al. A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis. Plant Cell, 2016. 28(4): p. 855-74 [PMID:27073231] Lozano-Sotomayor P, et al. Altered expression of the bZIP transcription factor DRINK ME affects growth and reproductive development in Arabidopsis thaliana. Plant J., 2016. 88(3): p. 437-451 [PMID:27402171] Boex-Fontvieille E, et al. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence. Front Plant Sci, 2016. 7: p. 1246 [PMID:27625656] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667]