PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_18380_f_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family NF-X1
Protein Properties Length: 250aa    MW: 27594.5 Da    PI: 8.4455
Description NF-X1 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_18380_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-NF-X118.15.8e-06183201120
        zf-NF-X1   1 CGkHkCqklCHeGpCppCpq 20 
                     CG H C  lCH+GpCp+Cp+
  Neem_18380_f_1 183 CG-HFCLLLCHPGPCPSCPK 201
                     **.***************96 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS500168.53867139IPR019787Zinc finger, PHD-finger
Gene3DG3DSA:3.30.40.102.1E-768139IPR013083Zinc finger, RING/FYVE/PHD-type
SuperFamilySSF578504.06E-669142No hitNo description
PROSITE profilePS500898.65370137IPR001841Zinc finger, RING-type
PROSITE patternPS01359070136IPR019786Zinc finger, PHD-type, conserved site
CDDcd060081.48E-10171216No hitNo description
SMARTSM004380.0049183201IPR000967Zinc finger, NF-X1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 250 aa     Download sequence    Send to blast
MTSTANYQQL LSDSDSDSDN GRPESFPDLS SSILKPYLES TNQSLLTASP SDLSKIRSFL  60
TSSSSGALSC LICLERIRPS DPTWHCSSLC YSIFHLICIQ SWARQASDLS ASFAASRLPI  120
SAAKAAESST WNCPKCRSQY SKSEIPKKYV CFCGKLEDPY SEDPWILPHS CGEVCNRPLQ  180
HNCGHFCLLL CHPGPCPSCP KLVKSSCFCG KIVRLMTVQK SATTGRARRV KRGRYTNADV  240
AEFKKRESVV
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator. May mediate E2- or E3-dependent ubiquitination. Required to gate light sensitivity during the night. Regulates the speed of the clock by acting in the feedback loop between CCA1, LHY and APRR1/TOC1. Promotes the expression of CCA1 at night but not by days. This activational effect is enhanced by interaction with ADO1/ZTL. Association with ADO1/ZTL is not leading to the degradation of NFXL2. Confers sensitivity to osmotic stress such as high salinity. Prevents H(2)O(2) production and abscisic acid accumulation. Part of a regulatory network that integrates the biosynthesis and action of abscisic acid, reactive oxygen species and cuticle components. {ECO:0000269|PubMed:16905136, ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:21429190, ECO:0000269|PubMed:22073231, ECO:0000269|PubMed:22516817}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with a peak of expression at or before dawn. Not regulated by biotic and abiotic stresses, by light and nutrient conditions or upon treatment with elicitors, chemicals, abscisic acid or phytohormones. {ECO:0000269|PubMed:21300918, ECO:0000269|PubMed:22073231}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006435741.21e-108NF-X1-type zinc finger protein NFXL2
RefseqXP_006486315.11e-108NF-X1-type zinc finger protein NFXL2
SwissprotQ9FFK82e-72NFXL2_ARATH; NF-X1-type zinc finger protein NFXL2
TrEMBLA0A2H5NJS11e-107A0A2H5NJS1_CITUN; Uncharacterized protein
TrEMBLA0A2H5NK351e-107A0A2H5NK35_CITUN; Uncharacterized protein
TrEMBLV4TGY21e-107V4TGY2_9ROSI; Uncharacterized protein
STRINGXP_006486315.11e-108(Citrus sinensis)
STRINGXP_006435741.11e-108(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM109542730
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G05660.12e-62sequence-specific DNA binding transcription factors;zinc ion binding;sequence-specific DNA binding transcription factors