PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_13613_f_2

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

MYB

Protein Properties

Length: 980aa MW: 109924 Da PI: 5.1425

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_13613_f_2	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	43.1	9.8e-14	8	53	2	48
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 g W Ede+l+ av ++G+++W++I++ + ++++kqck rw+ +l Neem_13613_f_2 8 GVWKNTEDEILKAAVMKYGKNQWARISSLLV-RKSAKQCKARWYEWL 53 78***************************.**********986 PP
2	Myb_DNA-binding	32.8	1.6e-10	60	103	2	48
SSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 2 grWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 WT eEde+l+++ k++++ W+tIa +g Rt+ qc +r+ k+l Neem_13613_f_2 60 TEWTREEDEKLLHLAKLMPTQ-WRTIAPIVG--RTPSQCLERYEKLL 103 68***************99.****8..********9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	22.008	2	57	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	5.7E-18	5	56	IPR009057	Homeodomain-like
SMART	SM00717	7.0E-15	6	55	IPR001005	SANT/Myb domain
CDD	cd00167	3.81E-12	10	53	No hit	No description
Pfam	PF13921	4.7E-13	10	70	No hit	No description
SuperFamily	SSF46689	7.19E-21	33	107	IPR009057	Homeodomain-like
CDD	cd11659	1.21E-30	55	106	No hit	No description
Gene3D	G3DSA:1.10.10.60	3.4E-14	57	104	IPR009057	Homeodomain-like
PROSITE profile	PS51294	16.443	58	107	IPR017930	Myb domain
SMART	SM00717	1.7E-12	58	105	IPR001005	SANT/Myb domain
Pfam	PF11831	6.2E-59	406	656	IPR021786	Pre-mRNA splicing factor component Cdc5p/Cef1

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009870	Biological Process	defense response signaling pathway, resistance gene-dependent
GO:0010204	Biological Process	defense response signaling pathway, resistance gene-independent
GO:0042742	Biological Process	defense response to bacterium
GO:0050832	Biological Process	defense response to fungus
GO:0009507	Cellular Component	chloroplast
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 980 aa Download sequence Send to blast
MRIMIKGGVW KNTEDEILKA AVMKYGKNQW ARISSLLVRK SAKQCKARWY EWLDPSIKKT 60 EWTREEDEKL LHLAKLMPTQ WRTIAPIVGR TPSQCLERYE KLLDAACAKD ENYEPGDDPR 120 KLRPGEIDPN PESKPARPDP VDMDEDEKEM LSEARARLAN TRGKKAKRKA REKQLEEARR 180 LASLQKRREL KAAGIDTRQR KRKRKGIDYN SEIPFEKKPP PGFFDVADED RPVEQVKFPT 240 TIEELEGKRR IDIEAQLRRQ DIAKNKIAQR QDAPSAILQA NKMNDPETVR KRSKLMLPAP 300 QISDNELEEI AKMGYAGDLA GNEELTEGSG ATRALLANYA QTPQQGMTPS RAPQRTPAGK 360 GDAIMMEAEN LARLRESQTP LLGGDNPELH PSDFSGVTPK KRDIQTPNPM LTPSATPGGV 420 ALTPRIGMTP SRDGSSFGMT PKGTPIRDEL HINEDMDVHD NAKLEQQRQA DLRRNLRSGL 480 RTLPQPKNEY QIVIQPPPEE NEEPEEKIEE DMSDRLAREK AEEEVRRQAL LRKRSKVLQR 540 ELPRPPVASL ELIRNSLLRA DGDKSSFVPP TSIEQADEII RKELLNLLEH DNAKYPLDEK 600 VEKKKKGNKR SANGSAAPIP VIEDFEEDEL QEADSLIKEE AQYLRMAMGH ENESLDEFVE 660 AHNTCLNDLM YFPTRNAYGL SSVAGNMEKL AALQSDFEIV KKKMDDDKEK ALHLEKKVKL 720 LTQGYEKRAE NLRNQIQSTV KQMETAGTEL ECFQALHKQE QLASSNRING LWEEVQKQKE 780 LERKLQQRYG DLSVELERIR HLMEECRVQA QKQEEIAAEK HALELAKAQA AANQATEQIP 840 EASESLPSEE PGSSMPVGPP CNEITGQQID TAHMDVDSGN EHAGPDMDGS VSNTVPSSAE 900 GTLPGNSHDQ LVDGMASDTT GNAAEASNPD GAFTKQESIV QETAKDDGFP NGNAIQVSGA 960 EGELQIKDIL PVSNGDHTDK

Sequence ? help Back to Top

Protein Sequence Length: 980 aa Download sequence Send to blast

MRIMIKGGVW KNTEDEILKA AVMKYGKNQW ARISSLLVRK SAKQCKARWY EWLDPSIKKT  60
EWTREEDEKL LHLAKLMPTQ WRTIAPIVGR TPSQCLERYE KLLDAACAKD ENYEPGDDPR  120
KLRPGEIDPN PESKPARPDP VDMDEDEKEM LSEARARLAN TRGKKAKRKA REKQLEEARR  180
LASLQKRREL KAAGIDTRQR KRKRKGIDYN SEIPFEKKPP PGFFDVADED RPVEQVKFPT  240
TIEELEGKRR IDIEAQLRRQ DIAKNKIAQR QDAPSAILQA NKMNDPETVR KRSKLMLPAP  300
QISDNELEEI AKMGYAGDLA GNEELTEGSG ATRALLANYA QTPQQGMTPS RAPQRTPAGK  360
GDAIMMEAEN LARLRESQTP LLGGDNPELH PSDFSGVTPK KRDIQTPNPM LTPSATPGGV  420
ALTPRIGMTP SRDGSSFGMT PKGTPIRDEL HINEDMDVHD NAKLEQQRQA DLRRNLRSGL  480
RTLPQPKNEY QIVIQPPPEE NEEPEEKIEE DMSDRLAREK AEEEVRRQAL LRKRSKVLQR  540
ELPRPPVASL ELIRNSLLRA DGDKSSFVPP TSIEQADEII RKELLNLLEH DNAKYPLDEK  600
VEKKKKGNKR SANGSAAPIP VIEDFEEDEL QEADSLIKEE AQYLRMAMGH ENESLDEFVE  660
AHNTCLNDLM YFPTRNAYGL SSVAGNMEKL AALQSDFEIV KKKMDDDKEK ALHLEKKVKL  720
LTQGYEKRAE NLRNQIQSTV KQMETAGTEL ECFQALHKQE QLASSNRING LWEEVQKQKE  780
LERKLQQRYG DLSVELERIR HLMEECRVQA QKQEEIAAEK HALELAKAQA AANQATEQIP  840
EASESLPSEE PGSSMPVGPP CNEITGQQID TAHMDVDSGN EHAGPDMDGS VSNTVPSSAE  900
GTLPGNSHDQ LVDGMASDTT GNAAEASNPD GAFTKQESIV QETAKDDGFP NGNAIQVSGA  960
EGELQIKDIL PVSNGDHTDK

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5mqf_L	0.0	2	800	3	799	Cell division cycle 5-like protein
5xjc_L	0.0	2	800	3	799	Cell division cycle 5-like protein
5yzg_L	0.0	2	800	3	799	Cell division cycle 5-like protein
5z56_L	0.0	2	800	3	799	Cell division cycle 5-like protein
5z57_L	0.0	2	800	3	799	Cell division cycle 5-like protein
5z58_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6ff4_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6ff7_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6icz_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6id0_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6id1_L	0.0	2	800	3	799	Cell division cycle 5-like protein
6qdv_O	0.0	2	800	3	799	Cell division cycle 5-like protein
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	185	204	KRRELKAAGIDTRQRKRKRK
2	199	204	RKRKRK

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence 'CTCAGCG' binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage. {ECO:0000250\|UniProtKB:Q99459, ECO:0000269\|PubMed:17298883, ECO:0000269\|PubMed:17575050, ECO:0000269\|PubMed:8917598}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00028	SELEX	Transfer from AT1G09770	Download

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006442689.1	0.0	cell division cycle 5-like protein
Swissprot	P92948	0.0	CDC5L_ARATH; Cell division cycle 5-like protein
TrEMBL	V4VS66	0.0	V4VS66_9ROSI; Uncharacterized protein
STRING	XP_006442689.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6453	27	42

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G09770.1	0.0	cell division cycle 5

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Li S, et al. MAC3A and MAC3B, Two Core Subunits of the MOS4-Associated Complex, Positively Influence miRNA Biogenesis. Plant Cell, 2018. 30(2): p. 481-494 [PMID:29437988]