PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Neem_11133_f_6

Organism

Azadirachta indica

Taxonomic ID

124943

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta

Family

HD-ZIP

Protein Properties

Length: 811aa MW: 89535.7 Da PI: 5.9357

Description

HD-ZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Neem_11133_f_6	genome	NGD	View Nucleic Acid

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	59.8	4.5e-19	27	85	3	57
--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 3 kRttftkeqleeLeelFeknrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 k ++t+eq+e+Le+l++++++ps +r++L +++ +++ +q+kvWFqNrR +ek+ Neem_11133_f_6 27 KYVRYTPEQVEALERLYHECPKPSSMRRQQLIRECpilsNIEPKQIKVWFQNRRCREKQ 85 5679*****************************************************97 PP
2	START	90.4	3.6e-29	158	282	2	124
HHHHHHHHHHHHHHHC-TT-EEEEEXCCTTEEEEEEESSS.SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-SEEEEEEEECTT..EEEEEE CS START 2 laeeaaqelvkkalaeepgWvkssesengdevlqkfeeskvdsgealrasgvvdmvlallveellddkeqWdetlakaetlevissg..galqlm 94 +aee+++e+++ka+ ++ Wv+++ +++g++++ +++ s++++g a+ra+g+v +++ v+e+l+d++ W ++++++e+++v+ +g g+++l Neem_11133_f_6 158 IAEETLTEFLSKATGTAVEWVQMPGMKPGPDSIGIVAISHGCPGVAARACGLVGLDPT-RVAEILKDRPSWYRDCRSVEVVNVLPTGnsGTVELL 251 789*****************************************************.8888888888********************** PP EEXXTTXX-SSX.EEEEEEEEEEE.TTS-EE CS START 95 vaelqalsplvp.RdfvfvRyirqlgagdwv 124 +++l+a+++l+p Rdf+ +Ry+ l++g++v Neem_11133_f_6 252 YMQLYAPTTLAPaRDFWLLRYTSVLEDGSLV 282 **********************9999876 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	15.661	22	86	IPR001356	Homeobox domain
SMART	SM00389	5.3E-16	24	90	IPR001356	Homeobox domain
SuperFamily	SSF46689	4.11E-17	26	90	IPR009057	Homeodomain-like
CDD	cd00086	5.33E-17	27	87	No hit	No description
Pfam	PF00046	1.1E-16	28	85	IPR001356	Homeobox domain
Gene3D	G3DSA:1.10.10.60	9.5E-19	29	85	IPR009057	Homeodomain-like
CDD	cd14686	1.10E-6	79	118	No hit	No description
PROSITE profile	PS50848	13.332	148	282	IPR002913	START domain
SuperFamily	SSF55961	3.3E-19	149	284	No hit	No description
Gene3D	G3DSA:3.30.530.20	1.5E-9	157	282	IPR023393	START-like domain
SMART	SM00234	8.5E-9	157	358	IPR002913	START domain
Pfam	PF01852	4.6E-26	158	282	IPR002913	START domain
Pfam	PF08670	6.1E-52	670	810	IPR013978	MEKHLA

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003677	Molecular Function	DNA binding
GO:0008289	Molecular Function	lipid binding

Sequence ? help Back to Top
Protein Sequence Length: 811 aa Download sequence Send to blast
MSFSLAEMMA VSSGCKDSNK MVMDNGKYVR YTPEQVEALE RLYHECPKPS SMRRQQLIRE 60 CPILSNIEPK QIKVWFQNRR CREKQRKEAS RLQAVNRKLT AMNKLLMEEN DRLQKQVSQL 120 ATLATTDTSC ESVVTSGQHH LTPQHPPRDA SPAGLLSIAE ETLTEFLSKA TGTAVEWVQM 180 PGMKPGPDSI GIVAISHGCP GVAARACGLV GLDPTRVAEI LKDRPSWYRD CRSVEVVNVL 240 PTGNSGTVEL LYMQLYAPTT LAPARDFWLL RYTSVLEDGS LVPWSVPEVL RPLYESSTLL 300 AQKTTMAALR HLRQISQEIS QPNVTGWGRR PAALRALSQR LSRGFNEALN GFSDDGWSML 360 ESDGIDDVTV HVNSSPNKMM GLQLSYANGF PSMSNAVLCA KASMLLQDVP PAILLRFLRE 420 HRSEWADSSI DAYSAAAVKA GPCSLPVPRA GNFGGQVILP LAHTIENEEA SISLVEDISE 480 MCRYQELWQY LIKSNCSLQF LEVIKLENMA HYREDMIVPS DIFLLQLCSG VDENAIGTCA 540 ELVFAPIDAS FSDDAPIIPS GFRIIPLDSG KDASSPNRTL DLASALEVGP TGNKTSGDYP 600 SNCGSTKSVI TIAFQFAFEI HLQENVASMA RQYVRSIIAS VQRVALALSP CRFGSQAGLR 660 PPPGTPEAHT LARWICQSYR CYLGAELFKT EGSESILKTL WNHSDAVLCC SLKALPVFTF 720 ANQAGLDMLE TTLVALQDIT LEKIFDDNGR KTLCSEFPQI MQQGFMCLQG GICLSSMGRP 780 ISYERAVAWK VLNEEESAHC ICFMFINWSF V

Sequence ? help Back to Top

Protein Sequence Length: 811 aa Download sequence Send to blast

MSFSLAEMMA VSSGCKDSNK MVMDNGKYVR YTPEQVEALE RLYHECPKPS SMRRQQLIRE  60
CPILSNIEPK QIKVWFQNRR CREKQRKEAS RLQAVNRKLT AMNKLLMEEN DRLQKQVSQL  120
ATLATTDTSC ESVVTSGQHH LTPQHPPRDA SPAGLLSIAE ETLTEFLSKA TGTAVEWVQM  180
PGMKPGPDSI GIVAISHGCP GVAARACGLV GLDPTRVAEI LKDRPSWYRD CRSVEVVNVL  240
PTGNSGTVEL LYMQLYAPTT LAPARDFWLL RYTSVLEDGS LVPWSVPEVL RPLYESSTLL  300
AQKTTMAALR HLRQISQEIS QPNVTGWGRR PAALRALSQR LSRGFNEALN GFSDDGWSML  360
ESDGIDDVTV HVNSSPNKMM GLQLSYANGF PSMSNAVLCA KASMLLQDVP PAILLRFLRE  420
HRSEWADSSI DAYSAAAVKA GPCSLPVPRA GNFGGQVILP LAHTIENEEA SISLVEDISE  480
MCRYQELWQY LIKSNCSLQF LEVIKLENMA HYREDMIVPS DIFLLQLCSG VDENAIGTCA  540
ELVFAPIDAS FSDDAPIIPS GFRIIPLDSG KDASSPNRTL DLASALEVGP TGNKTSGDYP  600
SNCGSTKSVI TIAFQFAFEI HLQENVASMA RQYVRSIIAS VQRVALALSP CRFGSQAGLR  660
PPPGTPEAHT LARWICQSYR CYLGAELFKT EGSESILKTL WNHSDAVLCC SLKALPVFTF  720
ANQAGLDMLE TTLVALQDIT LEKIFDDNGR KTLCSEFPQI MQQGFMCLQG GICLSSMGRP  780
ISYERAVAWK VLNEEESAHC ICFMFINWSF V

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor involved in the regulation of vascular development. May promote differentiation of precambial and cambial cells. {ECO:0000269\|PubMed:11402194, ECO:0000269\|PubMed:15598805}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin. Repressed by miR165. {ECO:0000269\|PubMed:17237362, ECO:0000269\|PubMed:8575317}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	FJ502239	5e-80	FJ502239.1 Poncirus trifoliata class III HD-Zip protein 8 (ATHB8) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006450706.1	0.0	homeobox-leucine zipper protein ATHB-8
Refseq	XP_024033889.1	0.0	homeobox-leucine zipper protein ATHB-8
Swissprot	Q39123	0.0	ATHB8_ARATH; Homeobox-leucine zipper protein ATHB-8
TrEMBL	A0A067GWM4	0.0	A0A067GWM4_CITSI; Uncharacterized protein
TrEMBL	V4UNG0	0.0	V4UNG0_9ROSI; Uncharacterized protein
STRING	XP_006450706.1	0.0	(Citrus clementina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2022	26	78

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G32880.1	0.0	homeobox gene 8

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Hategan L,Godza B,Kozma-Bognar L,Bishop GJ,Szekeres M Differential expression of the brassinosteroid receptor-encoding BRI1 gene in Arabidopsis. Planta, 2014. 239(5): p. 989-1001 [PMID:24488524] Baima S, et al. Negative feedback regulation of auxin signaling by ATHB8/ACL5-BUD2 transcription module. Mol Plant, 2014. 7(6): p. 1006-1025 [PMID:24777988] Kakehi J, et al. Mutations in ribosomal proteins, RPL4 and RACK1, suppress the phenotype of a thermospermine-deficient mutant of Arabidopsis thaliana. PLoS ONE, 2015. 10(1): p. e0117309 [PMID:25625317] Jia X, et al. Functional plasticity of miR165/166 in plant development revealed by small tandem target mimic. Plant Sci., 2015. 233: p. 11-21 [PMID:25711809] Liu S, et al. Expression of wild-type PtrIAA14.1, a poplar Aux/IAA gene causes morphological changes in Arabidopsis. Front Plant Sci, 2015. 6: p. 388 [PMID:26082787] Yamaguchi YL, et al. Root-Knot and Cyst Nematodes Activate Procambium-Associated Genes in Arabidopsis Roots. Front Plant Sci, 2017. 8: p. 1195 [PMID:28747918] Yamazaki K, et al. Suppression of DELLA signaling induces procambial cell formation in culture. Plant J., 2018. 94(1): p. 48-59 [PMID:29383774]