PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_10257_f_1
Organism
Azadirachta indica
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family HSF
Protein Properties Length: 437aa    MW: 49076 Da    PI: 4.4824
Description HSF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_10257_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind112.43.2e-35471382102
                     HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXX CS
    HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellek 96 
                     Fl+k++e++ed+++++++sws+  nsf+v+d+++f++++Lp++Fkhsnf+SF+RQLn+YgF+kv+ ++         weF+++ F  g+k+ll++
  Neem_10257_f_1  47 FLTKTFEMVEDPSTDSIVSWSRARNSFIVWDSHQFSTTLLPRHFKHSNFSSFIRQLNTYGFRKVDPDR---------WEFANEGFLGGQKHLLKT 132
                     9****************************************************************999.........****************** PP

                     XXXXXX CS
    HSF_DNA-bind  97 ikrkks 102
                     ikr+++
  Neem_10257_f_1 133 IKRRRN 138
                     ***987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-3743136IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.54E-3443136IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004152.1E-6043136IPR000232Heat shock factor (HSF)-type, DNA-binding
PfamPF004478.8E-3147136IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.8E-184770IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.8E-188597IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS00434086110IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.8E-1898110IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009644Biological Processresponse to high light intensity
GO:0010200Biological Processresponse to chitin
GO:0010286Biological Processheat acclimation
GO:0034605Biological Processcellular response to heat
GO:0034620Biological Processcellular response to unfolded protein
GO:0042542Biological Processresponse to hydrogen peroxide
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071456Biological Processcellular response to hypoxia
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 437 aa     Download sequence    Send to blast
MEGVRVKEEE TVTCAATAAA AASSSSSSSS FSPQPLEGLH DAGPPPFLTK TFEMVEDPST  60
DSIVSWSRAR NSFIVWDSHQ FSTTLLPRHF KHSNFSSFIR QLNTYGFRKV DPDRWEFANE  120
GFLGGQKHLL KTIKRRRNVS QSMQQQGGGA CVELGQYGLE GELERLKRDR NVLMAEIVKL  180
RQQQQQSRDQ MSAMEDRLLS TERKQQQMMT FLAKILNKPS FVQQFAQRNA HRRDLGSVDI  240
GRKRRLTARP SMENLQEEAI SMAPVRLESG QVVDYRVQDQ NELSTMETEI ETFFSSGLDN  300
ESSSDIGNPI AGSIPTSSGG NLDSVNEAIW EDLITEDLIV ENPEEIVVGD QSEADVEVED  360
LVATPTDWGE DLQDLVDQMG YLSLESVFIV TDRITWFFVQ QGVVKVAKGP TFVPVLLYPL  420
MIYLLLADSK TETCEDL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A4e-254213612120Heat shock factor protein 1
5d5u_B5e-254213621129Heat shock factor protein 1
5d5v_B5e-254213621129Heat shock factor protein 1
5d5v_D5e-254213621129Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1129135LKTIKRR
Functional Description ? help Back to Top
Source Description
UniProtDNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. {ECO:0000250}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006450864.10.0heat shock factor protein HSF30
RefseqXP_006450865.10.0heat shock factor protein HSF30
RefseqXP_006475902.10.0heat shock factor protein HSF30
RefseqXP_024953000.10.0heat shock factor protein HSF30
SwissprotP411521e-146HSF30_SOLPE; Heat shock factor protein HSF30
TrEMBLA0A2H5PZ190.0A0A2H5PZ19_CITUN; Uncharacterized protein
STRINGXP_006475902.10.0(Citrus sinensis)
STRINGXP_006450864.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM116722732
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G26150.11e-120heat shock transcription factor A2
Publications ? help Back to Top
  1. Scharf KD,Rose S,Thierfelder J,Nover L
    Two cDNAs for tomato heat stress transcription factors.
    Plant Physiol., 1993. 102(4): p. 1355-6
    [PMID:8278556]