PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ahy023024
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family LSD
Protein Properties Length: 177aa    MW: 18803.8 Da    PI: 8.5461
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Ahy#S59559090PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD142.41.1e-13731125
    zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
               C+gCr +L YPrGA++V+CalC+t+
  Ahy023024  7 CNGCRSILLYPRGATNVCCALCNTI 31
               ***********************97 PP

2zf-LSD150.53.3e-164670125
    zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
               CggCrtlL+Y+rGA+sVRC++C+tV
  Ahy023024 46 CGGCRTLLMYTRGATSVRCSCCQTV 70
               ************************9 PP

3zf-LSD149.56.7e-1685109125
    zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                Cg+Crt+L+YP+GApsV+CalC+ V
  Ahy023024  85 CGNCRTTLMYPYGAPSVKCALCQYV 109
                ***********************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010532.8E-12434IPR005735Zinc finger, LSD1-type
PfamPF069431.8E-11731IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010536.7E-184372IPR005735Zinc finger, LSD1-type
PfamPF069432.9E-134670IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010538.3E-1382112IPR005735Zinc finger, LSD1-type
PfamPF069432.1E-1485109IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 177 aa     Download sequence    Send to blast
MQSQLVCNGC RSILLYPRGA TNVCCALCNT ITSVPPPGME MSQLVCGGCR TLLMYTRGAT  60
SVRCSCCQTV NLAPPAPSQV AHVHCGNCRT TLMYPYGAPS VKCALCQYVT NVNMNNGRLP  120
IPVHRPNGTT NYGTVPSTST SMPQSQTQTV VIENPMTVDS NGKLVSNVVV GVTTDKK
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015957673.11e-124protein LSD1
RefseqXP_016190733.11e-124protein LSD1
RefseqXP_025639367.11e-124protein LSD1
RefseqXP_025691032.11e-124protein LSD1
SwissprotP940771e-74LSD1_ARATH; Protein LSD1
TrEMBLA0A445DN581e-123A0A445DN58_ARAHY; Uncharacterized protein
STRINGGLYMA05G30490.11e-112(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.75e-74LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]