PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ahy011400

Organism

Arachis hypogaea

Taxonomic ID

3818

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis

Family

HSF

Protein Properties

Length: 349aa MW: 40245.9 Da PI: 8.5686

Description

HSF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Ahy#S59553122	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HSF_DNA-bind	116.4	1.7e-36	138	229	2	102
HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS HSF_DNA-bind 2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 Fl+k+ye+++d+e++ ++swsen +sf+v++++efak +LpkyFkhsnf+SF+RQLn+YgF+kv++++ weF+++ F+ gkk+ll++i+ Ahy011400 138 FLRKTYEMVDDPETDPIVSWSENRDSFIVWESHEFAKVLLPKYFKHSNFSSFIRQLNTYGFRKVDSDR---------WEFANEGFQGGKKHLLKNIR 225 9**************************************************************999.........**************** PP XXXX CS HSF_DNA-bind 99 rkks 102 r+++ Ahy011400 226 RRSK 229 87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00415	4.7E-60	134	227	IPR000232	Heat shock factor (HSF)-type, DNA-binding
Gene3D	G3DSA:1.10.10.10	1.5E-38	134	227	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	9.11E-36	134	227	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00447	3.4E-32	138	227	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.7E-20	138	161	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.7E-20	176	188	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PROSITE pattern	PS00434	0	177	201	IPR000232	Heat shock factor (HSF)-type, DNA-binding
PRINTS	PR00056	5.7E-20	189	201	IPR000232	Heat shock factor (HSF)-type, DNA-binding

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 349 aa Download sequence Send to blast
XSHHYLYSTL NSNPSKTDKP QFQPTSKMVL LAHAGSGGGQ ACSPPQFNKA IAEEKPVEMV 60 RVKSEQVTSS CRFLQQNDDV SSDESDKKKS NSEVTEEEEP RVKEEVADDG AVNVSSSSSS 120 VELPKPMEGL NEAGPPPFLR KTYEMVDDPE TDPIVSWSEN RDSFIVWESH EFAKVLLPKY 180 FKHSNFSSFI RQLNTYGFRK VDSDRWEFAN EGFQGGKKHL LKNIRRRSKY NKLHQGAFID 240 PAKPCLEAEV EKLKEDQNIL KLEILKLRQQ QESSHVHISS VQDRIQNVQT KQYQMIYFLT 300 RMARKPTFME QLLQKIKRKR ELDGTDMLKR RRLLEPTPSV DYRCQQGHX

Sequence ? help Back to Top

Protein Sequence Length: 349 aa Download sequence Send to blast

XSHHYLYSTL NSNPSKTDKP QFQPTSKMVL LAHAGSGGGQ ACSPPQFNKA IAEEKPVEMV  60
RVKSEQVTSS CRFLQQNDDV SSDESDKKKS NSEVTEEEEP RVKEEVADDG AVNVSSSSSS  120
VELPKPMEGL NEAGPPPFLR KTYEMVDDPE TDPIVSWSEN RDSFIVWESH EFAKVLLPKY  180
FKHSNFSSFI RQLNTYGFRK VDSDRWEFAN EGFQGGKKHL LKNIRRRSKY NKLHQGAFID  240
PAKPCLEAEV EKLKEDQNIL KLEILKLRQQ QESSHVHISS VQDRIQNVQT KQYQMIYFLT  300
RMARKPTFME QLLQKIKRKR ELDGTDMLKR RRLLEPTPSV DYRCQQGHX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5d5u_B	6e-25	110	227	1	129	Heat shock factor protein 1
5d5v_B	6e-25	110	227	1	129	Heat shock factor protein 1
5d5v_D	6e-25	110	227	1	129	Heat shock factor protein 1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	317	331	RKRELDGTDMLKRRR
2	328	332	KRRRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE). Involved in heat stress responses. Seems to be involved in other environmental stress responses. Activates ascorbate peroxidase 2 (APX2) in addition to several heat shock protein (HSPs). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By heat stress, high light and hydrogen peroxide (H(2)O(2)). {ECO:0000269\|PubMed:16649111, ECO:0000269\|PubMed:17059409, ECO:0000269\|PubMed:17085506}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020999105.1	0.0	heat stress transcription factor A-2 isoform X2
Refseq	XP_025605794.1	0.0	heat stress transcription factor A-2 isoform X2
Swissprot	O80982	3e-80	HSFA2_ARATH; Heat stress transcription factor A-2
TrEMBL	A0A0B2PBI1	1e-130	A0A0B2PBI1_GLYSO; Heat stress transcription factor A-2
TrEMBL	A0A4P1R1U5	1e-130	A0A4P1R1U5_LUPAN; Uncharacterized protein
TrEMBL	I1LY11	1e-130	I1LY11_SOYBN; Uncharacterized protein
STRING	GLYMA13G16510.1	1e-131	(Glycine max)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G26150.1	6e-82	heat shock transcription factor A2

Publications ? help Back to Top
Liu HC,Charng YY Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development. Plant Physiol., 2013. 163(1): p. 276-90 [PMID:23832625] Jung HS, et al. Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(35): p. 14474-9 [PMID:23918368] Chauhan H,Khurana N,Agarwal P,Khurana JP,Khurana P A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment. PLoS ONE, 2013. 8(11): p. e79577 [PMID:24265778] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Weng M, et al. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ., 2014. 37(9): p. 2128-38 [PMID:24548003] Jang YH, et al. A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana. Plant J., 2014. 78(4): p. 591-603 [PMID:24580679] Stief A, et al. Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors. Plant Cell, 2014. 26(4): p. 1792-1807 [PMID:24769482] Dobrá J, et al. The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis. Plant Sci., 2015. 231: p. 52-61 [PMID:25575991] Yamauchi Y,Kunishima M,Mizutani M,Sugimoto Y Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression. Sci Rep, 2015. 5: p. 8030 [PMID:25619826] Shi H, et al. Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis. J. Pineal Res., 2015. 58(3): p. 335-42 [PMID:25711624] Mueller SP,Krause DM,Mueller MJ,Fekete A Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation. J. Exp. Bot., 2015. 66(15): p. 4517-26 [PMID:25977236] Nie S,Yue H,Xing D A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance. Plant Physiol., 2016. [PMID:26099269] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Hu Z, et al. Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis. Plant J., 2015. 84(6): p. 1178-91 [PMID:26576681] Lämke J,Brzezinka K,Bäurle I HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana. Transcription, 2016. 7(4): p. 111-4 [PMID:27383578] Wang X,Huang W,Liu J,Yang Z,Huang B Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress. Plant Biotechnol. J., 2017. 15(2): p. 237-248 [PMID:27500592] Chen ST,He NY,Chen JH,Guo FQ Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis. Plant J., 2017. 89(6): p. 1106-1118 [PMID:27943531] Kataoka R,Takahashi M,Suzuki N Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis. Plant Signal Behav, 2017. 12(11): p. e1376159 [PMID:28873003] Wang X,Zhuang L,Shi Y,Huang B Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis. Int J Mol Sci, 2018. [PMID:28914758] Llamas E,Pulido P,Rodriguez-Concepcion M Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. PLoS Genet., 2017. 13(9): p. e1007022 [PMID:28937985] Li X, et al. Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance. Plant Physiol., 2018. 176(4): p. 3027-3045 [PMID:29444814]