PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ahy010570
Organism
Arachis hypogaea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family C2H2
Protein Properties Length: 445aa    MW: 51375.6 Da    PI: 7.3366
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Ahy#S59555667PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.90.00068203225123
                EEETTTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                y C+ C    +rk++L+rH+r++
  Ahy010570 203 YFCEFCLNFMKRKEQLQRHMRKC 225
                78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541601.01E-2352170IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2701.3E-3755129No hitNo description
PfamPF117173.4E-2159117IPR025995RNA binding activity-knot of a chromodomain
CDDcd000241.07E-672117No hitNo description
SMARTSM002986.6E-773132IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2701.3E-37164214No hitNo description
PROSITE profilePS5172675.584169440IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.24E-111170441IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.304.3E-73228371IPR016181Acyl-CoA N-acyltransferase
PfamPF018533.1E-84230407IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00158281339No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0016747Molecular Functiontransferase activity, transferring acyl groups other than amino-acyl groups
Sequence ? help Back to Top
Protein Sequence    Length: 445 aa     Download sequence    Send to blast
MGSLEAPTTT ENGSTATPAG NGKSLATDGT ARVPPPEMTS EKPPDSDSSK RRRSSVLPLE  60
VGTRVMCRWR DGKYHPVKVI ERRKVSSSDP NDYEYYVHYT EFNRRLDEWV KLEQLDLESV  120
EAVVDEKVEE KGATGLKMTR HQKRKIDETH VEGHEELDAA SLREHEEFTK VKNIATIELG  180
RYEIETWYFS PFPPEYNDCL KLYFCEFCLN FMKRKEQLQR HMRKCDLKHP PGDEIYRSGT  240
LSMFEVDGKK NKVYGQNLCY LAKLFLDHKT LYYDVDLFLF YVLCECDDRG CHMVGYFSKE  300
KHSEESYNLA CILTLPPYQR KGYGKFLIAF SYELSKKEGK VGTPERPLSD LGLLSYRGYW  360
TRVLLDILKK HKGNISIKEL SDMTAIKAED ILTTLQSLEL IQYRKGQHVI CADPKVLDRH  420
LKAAGRGGLE VDVSKLIWTP YKEQS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1181654441282Histone acetyltransferase KAT8
4dnc_B1e-1181654441282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015954530.10.0histone acetyltransferase of the MYST family 2
RefseqXP_016187633.10.0histone acetyltransferase of the MYST family 2
RefseqXP_025641499.10.0histone acetyltransferase of the MYST family 2
RefseqXP_025688596.10.0histone acetyltransferase of the MYST family 2
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A445DWN70.0A0A445DWN7_ARAHY; Histone acetyltransferase
STRINGGLYMA06G47380.10.0(Glycine max)
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]