PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Ahy009510
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family C2H2
Protein Properties Length: 352aa    MW: 39789.2 Da    PI: 7.5655
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Ahy#S59549833PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H213.40.00022238263123
                EEET..TTTEEESSHHHHHHHHHH.T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                ++C    C++sF +k +L+ H r+ +
  Ahy009510 238 HRCDldGCSMSFMTKGELQLHRRNlC 263
                789999****************9877 PP

2zf-C2H211.40.00099263285323
                ET..TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   3 Cp..dCgksFsrksnLkrHirtH 23 
                Cp   Cgk Fs++ +   H+r+H
  Ahy009510 263 CPqkGCGKKFSSHKYALLHQRVH 285
                88889****************99 PP

3zf-C2H213.80.00018321347123
                EEET..TTTEEESSHHHHHHHHHH..T CS
    zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt..H 23 
                ykC+   Cg sF+  s++ rH r+  H
  Ahy009510 321 YKCKveGCGLSFRFVSDFSRHRRKtgH 347
                99*********************9777 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.602.0E-6229260IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576679.9E-5235260No hitNo description
SMARTSM003559.6238260IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.51261290IPR007087Zinc finger, C2H2
SMARTSM003550.53261285IPR015880Zinc finger, C2H2-like
SuperFamilySSF576676.54E-6262294No hitNo description
PROSITE patternPS000280263285IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.604.5E-5263289IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
Gene3DG3DSA:3.30.160.606.5E-11290315IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015711.739291320IPR007087Zinc finger, C2H2
SMARTSM003550.0025291315IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280293315IPR007087Zinc finger, C2H2
SuperFamilySSF576671.45E-11301344No hitNo description
Gene3DG3DSA:3.30.160.602.5E-12316344IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.22321347IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.494321352IPR007087Zinc finger, C2H2
PROSITE patternPS000280323347IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 352 aa     Download sequence    Send to blast
XCKCDSLDLD EELHRENPSA CKSNNEEAAS SSVSLANQPI LASIDDALTE LASESAKQCK  60
VQDNNTIYEE PVSSNVARGN TRSEAILELG CSEVAVETCS QEENELKIQP NNRINEEDNS  120
SPKTPLKEDI NGSEDKLSQD MLTEQESCKL SNPVPRSNAR KKRKTELDQI TENQLSCNNF  180
IRSPCEGLRP RATKIAPEKS EGDADQDDKE NPKARRDRKP SEVPAAHKNK KDDVEKPHRC  240
DLDGCSMSFM TKGELQLHRR NLCPQKGCGK KFSSHKYALL HQRVHDDKRP LKCPWKGCTM  300
SFKWAWARTE HIRVHTGEKP YKCKVEGCGL SFRFVSDFSR HRRKTGHYVK SD
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6a57_A7e-5623835023135Lysine-specific demethylase REF6
6a58_A7e-5623835023135Lysine-specific demethylase REF6
6a59_A7e-5623835023135Lysine-specific demethylase REF6
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1154163PRSNARKKRK
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025617297.10.0probable lysine-specific demethylase ELF6
SwissprotQ6BDA02e-64ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBLA0A445BCZ50.0A0A445BCZ5_ARAHY; Uncharacterized protein
STRINGGLYMA20G32160.11e-120(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.11e-66C2H2 family protein
Publications ? help Back to Top
  1. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  4. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]