PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AHYPO_016575-RA
Organism
Amaranthus hypochondriacus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Amaranthaceae; Amaranthus
Family bHLH
Protein Properties Length: 501aa    MW: 55562.3 Da    PI: 7.3615
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AHYPO_016575-RAgenomeBYUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.26e-13355401455
                      HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
              HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                      +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  AHYPO_016575-RA 355 NHVEAERQRREKLNQRFYALRAVVPNiS------KMDKASLLGDAISYITDLQ 401
                      799***********************66......*****************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.5E-4447232IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF474597.59E-19350417IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.085351400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.99E-14354405No hitNo description
Gene3DG3DSA:4.10.280.101.3E-18355414IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.8E-10355401IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.1E-15357406IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 501 aa     Download sequence    Send to blast
MGVNCEVNKE DKAMLESVVG IEACKFLMSR NNEDFVNEFS PISKLNLQQG LCKIVDSCSW  60
NYAIFWQIVS SKKDGRSILI WGDGHCRDPK EILAMERGDC GESNGGTSKK DEAKKKVLEK  120
LHACFGGSKE DSFVATLDRV SDVEMLYLTS MYYWFWLDSP VGPARCFTSG RPIWVSDGKS  180
CSNHYQTRAH LADCGRIQTV VFVPVNSGVL ELGSIRMVLE EQNVVQMAKH IFGEPHPFQA  240
KMCPKIFGCE LSLGAPISHS NNINDTPKLE DGAGFSAESH VGARAAHTYG SSSNGFCSVD  300
NGKKLIPEIN FGGLIPETQN PTLEQAKEEH LVQGSQPKPR KRGRKPANGR EEPLNHVEAE  360
RQRREKLNQR FYALRAVVPN ISKMDKASLL GDAISYITDL QMKVRMLEAE KELANPMHKN  420
IAIPEIDFQA RQGDALVHVS FPLDLHPASR VVKTLRENQI VAPEAIVSTT DNKIVHTFTI  480
RTQSGHAENL KEKLQAALSN *
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A1e-28349411264Transcription factor MYC2
5gnj_B1e-28349411264Transcription factor MYC2
5gnj_E1e-28349411264Transcription factor MYC2
5gnj_F1e-28349411264Transcription factor MYC2
5gnj_G1e-28349411264Transcription factor MYC2
5gnj_I1e-28349411264Transcription factor MYC2
5gnj_M1e-28349411264Transcription factor MYC2
5gnj_N1e-28349411264Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010679205.10.0PREDICTED: transcription factor bHLH3
SwissprotA0A3Q7H2161e-156MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A0K9Q9G30.0A0A0K9Q9G3_SPIOL; Uncharacterized protein
STRINGXP_010679205.10.0(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-142bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]