PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AHYPO_014398-RA

Organism

Amaranthus hypochondriacus

Taxonomic ID

28502

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Amaranthaceae; Amaranthus

Family

C2H2

Protein Properties

Length: 499aa MW: 55549.5 Da PI: 5.9786

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AHYPO_014398-RA	genome	BYU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	21.1	8.3e-07	254	275	2	23
EETTTTEEESSHHHHHHHHHHT CS zf-C2H2 2 kCpdCgksFsrksnLkrHirtH 23 C++Cgk F+r nL+ H+r H AHYPO_014398-RA 254 FCTICGKGFKRDANLRMHMRGH 275 6*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	2.14E-5	251	278	No hit	No description
SMART	SM00355	0.0026	253	275	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	12.03	253	280	IPR007087	Zinc finger, C2H2
Gene3D	G3DSA:3.30.160.60	9.5E-6	254	304	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE pattern	PS00028	0	255	275	IPR007087	Zinc finger, C2H2
SMART	SM00355	65	302	335	IPR015880	Zinc finger, C2H2-like
SMART	SM00355	36	340	362	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0010044	Biological Process	response to aluminum ion
GO:0010447	Biological Process	response to acidic pH
GO:0005634	Cellular Component	nucleus
GO:0003676	Molecular Function	nucleic acid binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 499 aa Download sequence Send to blast
MNSWLFTTFC SQDQPSWEDP SVLDYNMNIS PSFPKFNQSS QSSPFLVANS GNPGKIPKRD 60 GDEMSQTPDE GNWDPRTMLN NLSFLEQKIH QLQELVHMIA GQRAQVPGNQ DELVIQQQQQ 120 LITTDVTSII VQLISTAGSL LPSMKHNLSA VTPGLQLNRV LFPSAENVST GLMPQNNVGQ 180 GQQAVAEVQP VENPKPVDVM ANCATEMNCN MEEDHHDHEL KEDDEGKEEE HLPPGSYEIL 240 QLEKEEILAP HTHFCTICGK GFKRDANLRM HMRGHGDEYK TPAALAKPNK ESSSEKVLLK 300 RYSCPFVGCK RNKEHKKFQP LKTILCVKNH YKRTHCDKSY TCSRCHTKKF SVIADLKTHE 360 KHCGRDKWLC SCGTTFSRKD KLFGHIALFQ GHTPAIPCEE HKGTSGPSNL VESCEAANNA 420 PNMGFSFGSS VANVNVAPTV MDTRVNIEDS LFSLLNYDYS LNGLQDFPQT AFDDTANSFS 480 FLIPGEKDDM LCGSNDVD*

Sequence ? help Back to Top

Protein Sequence Length: 499 aa Download sequence Send to blast

MNSWLFTTFC SQDQPSWEDP SVLDYNMNIS PSFPKFNQSS QSSPFLVANS GNPGKIPKRD  60
GDEMSQTPDE GNWDPRTMLN NLSFLEQKIH QLQELVHMIA GQRAQVPGNQ DELVIQQQQQ  120
LITTDVTSII VQLISTAGSL LPSMKHNLSA VTPGLQLNRV LFPSAENVST GLMPQNNVGQ  180
GQQAVAEVQP VENPKPVDVM ANCATEMNCN MEEDHHDHEL KEDDEGKEEE HLPPGSYEIL  240
QLEKEEILAP HTHFCTICGK GFKRDANLRM HMRGHGDEYK TPAALAKPNK ESSSEKVLLK  300
RYSCPFVGCK RNKEHKKFQP LKTILCVKNH YKRTHCDKSY TCSRCHTKKF SVIADLKTHE  360
KHCGRDKWLC SCGTTFSRKD KLFGHIALFQ GHTPAIPCEE HKGTSGPSNL VESCEAANNA  420
PNMGFSFGSS VANVNVAPTV MDTRVNIEDS LFSLLNYDYS LNGLQDFPQT AFDDTANSFS  480
FLIPGEKDDM LCGSNDVD*

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. Together with STOP2, plays a critical role in tolerance to major stress factors in acid soils such as proton H(+) and aluminum ion Al(3+). Required for the expression of genes in response to acidic stress (e.g. ALMT1 and MATE), and Al-activated citrate exudation. {ECO:0000269\|PubMed:17535918, ECO:0000269\|PubMed:18826429, ECO:0000269\|PubMed:19321711, ECO:0000269\|PubMed:23935008}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00196	ampDAP	Transfer from AT1G34370	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By shock H(+) and Al(3+) treatments. {ECO:0000269\|PubMed:17535918}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021760450.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Refseq	XP_021760451.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Refseq	XP_021760452.1	0.0	protein SENSITIVE TO PROTON RHIZOTOXICITY 1-like
Swissprot	Q9C8N5	0.0	STOP1_ARATH; Protein SENSITIVE TO PROTON RHIZOTOXICITY 1
TrEMBL	A0A0K9R5A3	0.0	A0A0K9R5A3_SPIOL; Uncharacterized protein
STRING	XP_010676478.1	0.0	(Beta vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34370.2	1e-163	C2H2 family protein

Link Out ? help Back to Top
Phytozome	AHYPO_014398-RA

Publications ? help Back to Top
Kobayashi Y, et al. Molecular and physiological analysis of Al³⁺ and H⁺ rhizotoxicities at moderately acidic conditions. Plant Physiol., 2013. 163(1): p. 180-92 [PMID:23839867] Yokosho K,Yamaji N,Ma JF Global transcriptome analysis of Al-induced genes in an Al-accumulating species, common buckwheat (Fagopyrum esculentum Moench). Plant Cell Physiol., 2014. 55(12): p. 2077-91 [PMID:25273892] Geng X, et al. LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis. Plant J., 2017. 90(3): p. 491-504 [PMID:28181322] Balzergue C, et al. Low phosphate activates STOP1-ALMT1 to rapidly inhibit root cell elongation. Nat Commun, 2017. 8: p. 15300 [PMID:28504266] Pelagio-Flores R,Esparza-Reynoso S,Garnica-Vergara A,López-Bucio J,Herrera-Estrella A Trichoderma-Induced Acidification Is an Early Trigger for Changes in Arabidopsis Root Growth and Determines Fungal Phytostimulation. Front Plant Sci, 2017. 8: p. 822 [PMID:28567051] Jiang F, et al. Identification and characterization of suppressor mutants of stop1. BMC Plant Biol., 2017. 17(1): p. 128 [PMID:28738784] Daspute AA, et al. Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms. Front Plant Sci, 2017. 8: p. 1358 [PMID:28848571] Sharma A,Wai CM,Ming R,Yu Q Diurnal Cycling Transcription Factors of Pineapple Revealed by Genome-Wide Annotation and Global Transcriptomic Analysis. Genome Biol Evol, 2017. 9(9): p. 2170-2190 [PMID:28922793] Zhang Y, et al. The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis. Front Plant Sci, 2018. 9: p. 118 [PMID:29491872]