PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araha.4757s0002.1.p
Organism
Arabidopsis halleri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family GRF
Protein Properties Length: 529aa    MW: 56454.3 Da    PI: 9.425
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araha.4757s0002.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC78.37.6e-25196240145
                  WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                          d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e 
  Araha.4757s0002.1.p 196 DPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVEG 240
                          79****************************************985 PP
2QLQ51.53.1e-18132168137
                  QLQ   1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                          ++F+ +Q+++L++Q+l+yKy+ an+PvP+ Ll+ ++k
  Araha.4757s0002.1.p 132 GPFSLTQWAELEQQALIYKYITANVPVPSSLLLSLKK 168
                          59******************************99875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009511.3E-10132168IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166620.723133168IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088802.2E-12133165IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166725.954196240IPR014977WRC domain
PfamPF088793.4E-21197239IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009624Biological Processresponse to nematode
GO:0048364Biological Processroot development
GO:0048366Biological Processleaf development
GO:0061062Biological Processregulation of nematode larval development
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 529 aa     Download sequence    Send to blast
MDLGVRVSGH ENGSSPGQTE LGSGFSNKQE RSGFDGEDCW RSSKLSRTSS TDGFSSSSAS  60
AKTLSFHQGI PLLRSTTIDP RKGQEHMLSF SSTSDKSDVS PYLQYCRNSG YGLGGMMNTS  120
NMHGNLLTGV KGPFSLTQWA ELEQQALIYK YITANVPVPS SLLLSLKKSF FPYGSLPPNS  180
FGWGSFHLGF SGGNMDPEPG RCRRTDGKKW RCSRDAVPDQ KYCERHINRG RHRSRKPVEG  240
QNGHNTNAAV ASAAASTAAA VSKAAAGTSA IAMRGSDNNN SLTAAVGTHH HANNQSTDSL  300
ANRVQNSRGA LVFPATMNLQ PKETHPKQSN NSFEFGLISS DSLLNPSHKQ ATYANSSKGF  360
GSYLDFSNQA KHAGNHHNDD SWPEELKSDW TQLSMSIPMA PSSPVQDKLA LSPLRLSREF  420
DPAIHMGLGV NTEFLEPGKK TNNWIPISWG NNNSMGGPLG EVLNSTTNSP KFGSSPTGVL  480
QKSTFGSLSN SSSGSSTIIG DNNNKNGDGK DPLGPTTLMN TSATAPSL*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269|PubMed:12974814, ECO:0000269|PubMed:15326298, ECO:0000269|PubMed:22419826, ECO:0000269|PubMed:22751317}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraha.4757s0002.1.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503, ECO:0000269|PubMed:20023165, ECO:0000269|PubMed:22419826}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY1026340.0AY102634.1 Arabidopsis thaliana transcription activator (GRF1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002878638.10.0growth-regulating factor 1
SwissprotO810010.0GRF1_ARATH; Growth-regulating factor 1
TrEMBLD7LE480.0D7LE48_ARALL; Uncharacterized protein
STRINGfgenesh2_kg.4__207__AT2G22840.10.0(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM14542886
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22840.10.0growth-regulating factor 1
Publications ? help Back to Top
  1. Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P
    Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves.
    Plant Cell, 2013. 25(9): p. 3570-83
    [PMID:24076976]
  2. Liu J,Rice JH,Chen N,Baum TJ,Hewezi T
    Synchronization of developmental processes and defense signaling by growth regulating transcription factors.
    PLoS ONE, 2014. 9(5): p. e98477
    [PMID:24875638]
  3. Cao Y,Han Y,Jin Q,Lin Y,Cai Y
    Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
    Front Plant Sci, 2016. 7: p. 1750
    [PMID:27933074]