PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Araha.11126s0008.2.p | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 469aa MW: 52855.2 Da PI: 9.472 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 73.9 | 1.7e-23 | 103 | 168 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l+++ +++ l+++a++L v +rRRiYDi+NVLe+++++++++kn+++wkg Araha.11126s0008.2.p 103 RKQKSLGLLCTNFLALYNRDGIEMIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 168 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 73.8 | 1.9e-23 | 238 | 316 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +se++i++l+e+ak L+ + + + RR+YDi+NVL+++nliek ++k++++w g Araha.11126s0008.2.p 238 RREKSLGLLTQNFIKLFICSEARIISLDEAAKLLLGDahntsIM--RMRRLYDIANVLSSMNLIEKthtldSRKPAFKWLG 316 689**********************************9987544..78********************9999*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.7E-26 | 99 | 169 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 2.58E-16 | 102 | 166 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.6E-28 | 103 | 168 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 2.9E-20 | 104 | 168 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 1.1E-22 | 236 | 317 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 6.3E-28 | 238 | 316 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 1.4E-18 | 240 | 316 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 6.65E-13 | 240 | 317 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 469 aa Download sequence Send to blast |
MEMSDMDLTN SASPLNYDTT LPKFGGVLLL RRRRSQKIQI GAQVSSQIPP LSFWKSLQNT 60 ISNSQSQKTS FASIMSDLSP ERFKLPITSM PESSSSLHHS YSRKQKSLGL LCTNFLALYN 120 RDGIEMIGLD DAASKLGVER RRIYDIVNVL ESVGVLTRRA KNQYTWKGFA AIPGALKELQ 180 EEGVKDTFHR FYVNENVKGS DDEDDDEESS QPHSSSQTDS SKPGSLPQSS DPSKIDNRRE 240 KSLGLLTQNF IKLFICSEAR IISLDEAAKL LLGDAHNTSI MRMRRLYDIA NVLSSMNLIE 300 KTHTLDSRKP AFKWLGYNGE PTFTLSSDLM LLESRKRAFG TDLTNVNVKR SKSSSSSQEN 360 ATERKLKMKK HSTPESSYNK SFDVHEPRHG SRGYHFGPFA PGTGTYPTAG LEDNSRRAFD 420 VENLNSDYRP SYQNQVLKDL FSHYMDAWKT WYSEVTQKNP SPNTSQHR* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 1e-37 | 102 | 308 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Araha.11126s0008.2.p |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT004258 | 0.0 | BT004258.1 Arabidopsis thaliana clone RAFL15-19-A14 (R20743) putative DP-E2F protein 1 (At3g48160) mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_020880369.1 | 0.0 | E2F transcription factor-like E2FE isoform X2 | ||||
Swissprot | Q8LSZ4 | 0.0 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | D7LRJ4 | 0.0 | D7LRJ4_ARALL; Uncharacterized protein | ||||
STRING | fgenesh2_kg.5__1169__AT3G48160.2 | 0.0 | (Arabidopsis lyrata) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 0.0 | DP-E2F-like 1 |
Link Out ? help Back to Top | |
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Phytozome | Araha.11126s0008.2.p |
Publications ? help Back to Top | |||
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