PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aradu.VW26U

Organism

Arachis duranensis

Taxonomic ID

130453

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis

Family

E2F/DP

Protein Properties

Length: 460aa MW: 50706.8 Da PI: 4.8988

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aradu.VW26U	genome	NCGR_PGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	82.2	4.4e-26	146	211	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++e g+++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Aradu.VW26U 146 RYDSSLGLLTKKFVNLLKHAEGGNLDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKIKNRIHWKG 211 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	4.1E-28	143	212	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	5.83E-17	146	209	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	4.4E-34	146	211	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	4.5E-24	148	211	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	2.24E-46	222	328	No hit	No description
SuperFamily	SSF144074	1.28E-31	223	328	No hit	No description
Pfam	PF16421	2.3E-31	227	326	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 460 aa Download sequence Send to blast
MSAAAGASKL HESPPTEASG IPNRPPPKRH LAFASTKPPF APLDDYRSFS GPHCRKASDQ 60 EQEAVVVRSP YMKRKSGGVN DRLRETQEQS NSPGYANTVN SPLQTPGSTK GGRTYNKSRA 120 SKEGRSVPQT PILEAGSPSL TPSSCRYDSS LGLLTKKFVN LLKHAEGGNL DLNKAAETLE 180 VQKRRIYDIT NVLEGIGLIE KKIKNRIHWK GIDCSTSGGI DDDVSMLKED VEKLSLEEHR 240 LDDQIREMQE RLRILSEDEN NKKMLFVTED DIKSLPEFQN ETLIAIKAPH GTTLEVPEPE 300 EAVDYPQRRY RVILRSTMGP IDVFLISQFE EKFEEMSFPL ASSSGSNEHQ AAELLPVECN 360 DKAPEAPAQL SSNTCSDLNT VQEFAGGMMK IVPSAADTDA DYWLLSDVEA SITDMWKTDS 420 SVDWDGVDML NSDFVLISRP QTPSSGFAEA PSAVASIPHR

Sequence ? help Back to Top

Protein Sequence Length: 460 aa Download sequence Send to blast

MSAAAGASKL HESPPTEASG IPNRPPPKRH LAFASTKPPF APLDDYRSFS GPHCRKASDQ  60
EQEAVVVRSP YMKRKSGGVN DRLRETQEQS NSPGYANTVN SPLQTPGSTK GGRTYNKSRA  120
SKEGRSVPQT PILEAGSPSL TPSSCRYDSS LGLLTKKFVN LLKHAEGGNL DLNKAAETLE  180
VQKRRIYDIT NVLEGIGLIE KKIKNRIHWK GIDCSTSGGI DDDVSMLKED VEKLSLEEHR  240
LDDQIREMQE RLRILSEDEN NKKMLFVTED DIKSLPEFQN ETLIAIKAPH GTTLEVPEPE  300
EAVDYPQRRY RVILRSTMGP IDVFLISQFE EKFEEMSFPL ASSSGSNEHQ AAELLPVECN  360
DKAPEAPAQL SSNTCSDLNT VQEFAGGMMK IVPSAADTDA DYWLLSDVEA SITDMWKTDS  420
SVDWDGVDML NSDFVLISRP QTPSSGFAEA PSAVASIPHR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	2e-23	138	212	1	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	Aradu.VW26U

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015970602.1	0.0	transcription factor E2FA
Swissprot	Q9FNY0	1e-153	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A445CRF6	0.0	A0A445CRF6_ARAHY; Uncharacterized protein
STRING	GLYMA02G35850.1	0.0	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1947	34	90

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-157	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]