PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aradu.VSE1D
Organism
Arachis duranensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family E2F/DP
Protein Properties Length: 426aa    MW: 48854.9 Da    PI: 9.2119
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aradu.VSE1DgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP76.72.3e-241984171
      E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                 rk+ksL+ll+++flkl++k +   + l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  Aradu.VSE1D 19 RKQKSLGLLCTNFLKLYNKDSIHLIGLDDAASRL---GV--ERRRIYDIVNVLESVGVLSRKAKNQYTWKG 84
                 79*****************999************...**..****************************98 PP
2E2F_TDP75.84.5e-24153233171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ +      +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Aradu.VSE1D 153 RREKSLALLTQNFVKLFVCSNIEMISLDEAAKLLLGNahntsIMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 233
                  689********************************999***999**************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.2E-261585IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.72E-161882IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.4E-281984IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-202084IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.102.5E-23151234IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.8E-31153233IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.6E-19155233IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.17E-14155234IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 426 aa     Download sequence    Send to blast
MSSPTPTMDP SSRHYSYNRK QKSLGLLCTN FLKLYNKDSI HLIGLDDAAS RLGVERRRIY  60
DIVNVLESVG VLSRKAKNQY TWKGFAAIPG ALQELKDEGL RENPYGFDGD NEIAKLSDDE  120
DDEETMSNPS NGSQNDKSNP NASLTKSLKP ENRREKSLAL LTQNFVKLFV CSNIEMISLD  180
EAAKLLLGNA HNTSIMRTKV RRLYDIANVL SSMNLIEKTH TTDTRKPAFR WLGLRGKPWS  240
ESGDSALNSN HSGESRKRMF GEDITNISFK RNKVDPFMNA ENSCKSYSKI QDQLENDDDS  300
CWQAHTDKGI VKQERKQNSK GYHFGPFAPE YVSKNGGASE NTNVKQVHDW ESLSNVYRPR  360
YQNQVLYKEW KLRWLLIDSH SSFVWFGYTK LENSKVYALR DLFSHYMEAW KSWYSEVAGK  420
RPIQIL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-38182253228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAradu.VSE1D
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015967699.10.0E2F transcription factor-like E2FE
RefseqXP_025701629.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-129E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A444Z2R90.0A0A444Z2R9_ARAHY; Uncharacterized protein
STRINGXP_007155383.11e-180(Phaseolus vulgaris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-131DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]