PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Aradu.K3S1H | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 471aa MW: 51564.6 Da PI: 5.0792 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 84.9 | 6.1e-27 | 151 | 216 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL++lt+kf++l+++se+g+++ln++a++L +v k+RRiYDi+NVLe+++liekk kn+i+wkg Aradu.K3S1H 151 RYDNSLGMLTKKFVNLVKHSEDGNLDLNQAAETL---EV--KKRRIYDITNVLEGIGLIEKKLKNRIHWKG 216 689*******************************...99..9***************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.3E-28 | 148 | 218 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.41E-17 | 151 | 214 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.7E-34 | 151 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 9.7E-25 | 153 | 216 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 8.11E-32 | 228 | 332 | No hit | No description |
Pfam | PF16421 | 1.1E-32 | 231 | 330 | IPR032198 | E2F transcription factor, CC-MB domain |
CDD | cd14660 | 3.14E-47 | 231 | 332 | No hit | No description |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0008284 | Biological Process | positive regulation of cell proliferation | ||||
GO:0009733 | Biological Process | response to auxin | ||||
GO:0010090 | Biological Process | trichome morphogenesis | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051302 | Biological Process | regulation of cell division | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0005737 | Cellular Component | cytoplasm | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 471 aa Download sequence Send to blast |
MSGGAGPPPQ HTKPDDSGVP IRPPLKRHLA FASMKPSFAQ PDEYHSFSSS SGAPDSGRKL 60 AADQQAEVVV VRSPHIKRKG GMTNIEGDSQ KLSNVPGSAN AASSPFKTPV SSKGGRTHAK 120 SKVSKEGMQC PQTPISNSGS PSPLTPAGSC RYDNSLGMLT KKFVNLVKHS EDGNLDLNQA 180 AETLEVKKRR IYDITNVLEG IGLIEKKLKN RIHWKGTESS SGDVDGDISM LKEEVERLSL 240 EEHRLDDRIR EMQERLRSLS EDENKQKFLF VTEEDIKAVP CFQNETLIAI KAPHGTTLEV 300 PDPEEAVDYL QRRYRIILRS TMGPIDVYLI SQFEERFEEI NGPEPPVSLP LPSSSGSNEP 360 PVAETVPAEC SAKGLEPQPQ IPSHTYSDLN TSQDFGGGMM KIVPSDADND ADYWLLSDAD 420 ISITDMWRTD SSVDWNGVDM LHPDFGNIPR PQTPSSGIAE TPSTVTNPNQ R |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 1e-22 | 146 | 217 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | Aradu.K3S1H |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | BT093046 | 5e-61 | BT093046.1 Soybean clone JCVI-FLGm-15I8 unknown mRNA. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_015951408.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 1e-158 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A445E7B2 | 0.0 | A0A445E7B2_ARAHY; Uncharacterized protein | ||||
STRING | AES62703 | 0.0 | (Medicago truncatula) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF1947 | 34 | 90 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 1e-151 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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