PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aradu.HB8K6
Organism
Arachis duranensis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family E2F/DP
Protein Properties Length: 374aa    MW: 41985 Da    PI: 9.3832
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aradu.HB8K6genomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.71.7e-221681171
      E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                 rk+k L+ll+++fl+l+++ + + + l+++a +L    v  +rRRiYDi+N+Le+++++++k+kn+++wkg
  Aradu.HB8K6 16 RKQKALGLLCTNFLSLYNRHDVQFIGLDDAAARL---GV--ERRRIYDIVNILESIGVLARKAKNQYTWKG 81
                 79*****************999************...**..****************************98 PP
2E2F_TDP75.55.4e-24155235171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  r+eksL lltq+f+kl+ +s+ ++++l+e+a+ L+ +      +++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Aradu.HB8K6 155 RREKSLALLTQNFVKLFVCSNIEMISLDEAANLLLGDghsssLMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 235
                  689**************************************9999*************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.6E-241482IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.72E-151579IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.7E-261681IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.1E-191781IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.2E-23151236IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.4E-31155235IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023193.1E-19157235IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.62E-13157236IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MASSASTSRH SVPQSRKQKA LGLLCTNFLS LYNRHDVQFI GLDDAAARLG VERRRIYDIV  60
NILESIGVLA RKAKNQYTWK GFGAIPGAFH ELKEEGLREN TYAFEGGNDN LKGSDDEDDE  120
EAFSNPGTGS QNEKSNSNSN SNSTTLSKSL KNDNRREKSL ALLTQNFVKL FVCSNIEMIS  180
LDEAANLLLG DGHSSSLMRT KVRRLYDIAN VLSSMNLIEK THTTDTRKPA FRWLGLRGKA  240
PNESIQNCSN PNESRKRAFG SDVTNISFER NIVELGDFAS KKLKKLDNGS DIGQANSFQQ  300
ASKGFQFGPF APSYVPKVEI PENNSVKKFH DWDSLAIKHR PQYQNQALRE LFSHYMEAWK  360
SWYSEVVGKN PMQI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-40152273228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAradu.HB8K6
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015967906.10.0E2F transcription factor-like E2FE
RefseqXP_025604340.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-127E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A445EPG30.0A0A445EPG3_ARAHY; Uncharacterized protein
STRINGGLYMA05G01760.20.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-126DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]