PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aradu.GGI7X
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family HB-other
Protein Properties Length: 257aa    MW: 29636.3 Da    PI: 5.4771
Description HB-other family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aradu.GGI7XgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox14.18.3e-05460751
                 --HHHHHHHHHHHHH..SSS--HHHHHHHHHHC..........TS-HHHHHHHHHHH CS
     Homeobox  7 ftkeqleeLeelFek..nrypsaeereeLAkkl..........gLterqVkvWFqNr 51
                 f+ ++++eLe+ +++  ++ ++++  +  A +           +Lt +qV+ WFqN+
  Aradu.GGI7X  4 FSIDEVNELERIYKEmgEKSVDQNFCKSVAISFssssrragkaSLTWEQVRHWFQNK 60
                 7778889999999966688888888888888888888999998*************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF167198.7E-37107234IPR032001SAWADEE domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006306Biological ProcessDNA methylation
GO:0006346Biological Processmethylation-dependent chromatin silencing
GO:0031047Biological Processgene silencing by RNA
GO:0003682Molecular Functionchromatin binding
Sequence ? help Back to Top
Protein Sequence    Length: 257 aa     Download sequence    Send to blast
MDRFSIDEVN ELERIYKEMG EKSVDQNFCK SVAISFSSSS RRAGKASLTW EQVRHWFQNK  60
LKESETNVAS TTSSMNLYID LSEASVLRNG QKSSSNAKGK RAEDISELTF EARSSKDVAW  120
HDVASFLNYR VLSTGELEVR IRYAGFGKEQ DEWINVKEGV RERSIPLEPS ECHKVNDGDL  180
ILCFLEKHDY ALYVDARVVK VLRRLHGPTD CRCIFIVRYV HDKTEEGVSW NRLCCRPTQE  240
EYVPEEIPLN PLEDLWG
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4iup_A3e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iup_B3e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuq_A4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuq_B4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iur_A4e-521062392135SHH1 SAWADEE
4iur_B4e-521062392135SHH1 SAWADEE
4iut_A4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iut_B4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuu_A4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuu_B4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuv_A4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
4iuv_B4e-521062392135SAWADEE HOMEODOMAIN HOMOLOG 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in RNA-directed DNA methylation (RdDM). Required for the silencing of some endogenous RdDM targets and accumulation of 24-nt siRNAs, but not for the production of Pol V-dependent transcripts. Functions in transcriptional silencing through both DNA methylation-dependent and -independent pathways. Required for both maintenance and de-novo DNA methylation. Plays a role in the recruitment of Pol IV to genomic regions associated with K9 methylated histone H3 that are targets for RdDM. {ECO:0000269|PubMed:21811420, ECO:0000269|PubMed:22064704, ECO:0000269|PubMed:23636332, ECO:0000269|PubMed:23637343}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAradu.GGI7X
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015938470.10.0protein SAWADEE HOMEODOMAIN HOMOLOG 1
SwissprotQ9XI473e-78SHH1_ARATH; Protein SAWADEE HOMEODOMAIN HOMOLOG 1
TrEMBLA0A445BPY70.0A0A445BPY7_ARAHY; Uncharacterized protein
STRINGXP_004510301.11e-118(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF27041415
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G18380.13e-45sequence-specific DNA binding transcription factors;sequence-specific DNA binding
Publications ? help Back to Top
  1. Liu J, et al.
    An atypical component of RNA-directed DNA methylation machinery has both DNA methylation-dependent and -independent roles in locus-specific transcriptional gene silencing.
    Cell Res., 2011. 21(12): p. 1691-700
    [PMID:22064704]
  2. Law JA, et al.
    Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
    Nature, 2013. 498(7454): p. 385-9
    [PMID:23636332]
  3. Ma L, et al.
    Angiosperms Are Unique among Land Plant Lineages in the Occurrence of Key Genes in the RNA-Directed DNA Methylation (RdDM) Pathway.
    Genome Biol Evol, 2015. 7(9): p. 2648-62
    [PMID:26338185]
  4. Wang F,Axtell MJ
    AGO4 is specifically required for heterochromatic siRNA accumulation at Pol V-dependent loci in Arabidopsis thaliana.
    Plant J., 2017. 90(1): p. 37-47
    [PMID:28002617]