PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aradu.1PF9A
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family E2F/DP
Protein Properties Length: 547aa    MW: 61241.3 Da    PI: 5.7416
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aradu.1PF9AgenomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.61.8e-27246311171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                  r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Aradu.1PF9A 246 RYDSSLGLLTKKFINLIKQAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 311
                  6899******************************...99..****************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.3E-29244313IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.0E-35246311IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467855.03E-17246309IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023191.3E-24248311IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146601.21E-44322426No hitNo description
SuperFamilySSF1440742.48E-30324426No hitNo description
PfamPF164216.1E-32327426IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 547 aa     Download sequence    Send to blast
MSGTRAPPAA ASPSEQIMRR QLPLSTMKPP FAASVDYHRF APDHLHHNRR TVDHEPEAIV  60
VKSSVWITCL VVDLVELVAD ELEELNYGVH KVKCRLPSPS PHGSDILVLQ EGSKWLGKQF  120
RLNDFDYPNI GLGGFIIYTF LGILTTNGDI CLHVLRLHFS GGTFHISIYP IKQLKRKSNT  180
TDFEADSGDR VNHVSMGAAN NPFQTPKSGK IGKGGKSSRL TKCNRSGPQT PGSPSGNNLT  240
PVGPCRYDSS LGLLTKKFIN LIKQAEDGIL DLNKAADTLE VQKRRIYDIT NVLEGIGLIE  300
KKLKNRIQWK GLDVSRPGEP EDSFSSLQAE VENLTMKECR LDEQIREMQE RLSDLSENEN  360
SEKLLFVTEE DIKNLPCFQN ETLIAIKAPH GTTLEVSDPD EAVDYPQRRY RIVLRSTMGP  420
IDVYLVRYAY FSRILAVFLK HLPQGSFCYC HGKFEEKFEE INGADVAPEF QPTPEFKNHE  480
PTVVVEDNGR DIAVQGQDGQ IPSSDFTSTQ DFVSGIVKIV PSDVDSHADY WLLSDADVSI  540
TDMWRTE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-26241312274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAradu.1PF9A
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015951676.10.0transcription factor E2FB isoform X6
SwissprotQ9FV711e-125E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A445E5510.0A0A445E551_ARAHY; Uncharacterized protein
STRINGXP_004506213.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF2872522
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.31e-122E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]