PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aqcoe3G281100.1.p

Organism

Aquilegia coerulea

Taxonomic ID

218851

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia

Family

E2F/DP

Protein Properties

Length: 480aa MW: 52569.5 Da PI: 4.5064

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aqcoe3G281100.1.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	81.8	5.7e-26	153	218	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++ +++gi++ln++a++L +v ++RRiYDi+NVLe+++liek+ kn+i+wkg Aqcoe3G281100.1.p 153 RYNSSLGLLTKKFINLIKYADDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKTLKNRISWKG 218 6789****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	5.6E-27	151	220	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	3.1E-32	153	218	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.29E-16	153	216	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	5.6E-23	155	218	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	1.33E-33	231	335	No hit	No description
Pfam	PF16421	8.5E-34	234	333	IPR032198	E2F transcription factor, CC-MB domain
CDD	cd14660	2.23E-47	234	335	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 480 aa Download sequence Send to blast
MSGSGVANRT AQPFEQIVQR QLPFTSMKPP FVCPDNYHRF SGGGGGGGGG ATGAGNREVV 60 GDKPISEAIG VKSPQLKRKT DTEDYEAESS EYTSIPGYSE VAKSPFRTPV SGKGSRIYSR 120 SKVPKYNRPA PQTPMSNAGS PSGMDLTAVG TCRYNSSLGL LTKKFINLIK YADDGILDLN 180 KAAETLEVQK RRIYDITNVL EGIGLIEKTL KNRISWKGFD DSRQGEGGDN ANMLQAEVEN 240 LSMEEHRLDD RIREMQETLR DLSEDENNQK WLFVTEEDIK SLPCFQNETL IAIKAPHGTT 300 LEVPDPDEAV DYPQRRYRIV LSSTMGPIDV YLVSQFEEKF EEDNDVETPS SIPLPSSSGS 360 NEKKQATTIA MEEGRREEMD NQGQDTNRMS SEVIASQDFV GGIMKIVPSD VDSDADYWLL 420 SDAGVSITDM WKTDPGVDWG GVGALNTEDF VKTAVSIPRP HTTPSGIIEM PSAANPSQR*

Sequence ? help Back to Top

Protein Sequence Length: 480 aa Download sequence Send to blast

MSGSGVANRT AQPFEQIVQR QLPFTSMKPP FVCPDNYHRF SGGGGGGGGG ATGAGNREVV  60
GDKPISEAIG VKSPQLKRKT DTEDYEAESS EYTSIPGYSE VAKSPFRTPV SGKGSRIYSR  120
SKVPKYNRPA PQTPMSNAGS PSGMDLTAVG TCRYNSSLGL LTKKFINLIK YADDGILDLN  180
KAAETLEVQK RRIYDITNVL EGIGLIEKTL KNRISWKGFD DSRQGEGGDN ANMLQAEVEN  240
LSMEEHRLDD RIREMQETLR DLSEDENNQK WLFVTEEDIK SLPCFQNETL IAIKAPHGTT  300
LEVPDPDEAV DYPQRRYRIV LSSTMGPIDV YLVSQFEEKF EEDNDVETPS SIPLPSSSGS  360
NEKKQATTIA MEEGRREEMD NQGQDTNRMS SEVIASQDFV GGIMKIVPSD VDSDADYWLL  420
SDAGVSITDM WKTDPGVDWG GVGALNTEDF VKTAVSIPRP HTTPSGIIEM PSAANPSQR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	4e-22	153	219	7	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010262959.1	0.0	PREDICTED: transcription factor E2FA-like
Refseq	XP_019053996.1	0.0	PREDICTED: transcription factor E2FA-like
Swissprot	Q9FV71	1e-149	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2G5F1E1	0.0	A0A2G5F1E1_AQUCA; Uncharacterized protein
STRING	Aquca_002_00087.1	0.0	(Aquilegia coerulea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	1e-143	E2F transcription factor 3

Link Out ? help Back to Top
Phytozome	Aqcoe3G281100.1.p

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]