PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aqcoe1G433300.1.p
Organism
Aquilegia coerulea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia
Family E2F/DP
Protein Properties Length: 480aa    MW: 53020.3 Da    PI: 4.7537
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aqcoe1G433300.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.77.1e-27153218171
            E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                        r+++sL+llt+kf++ll+++e+g+++ln++a+ L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Aqcoe1G433300.1.p 153 RYDSSLGLLTKKFINLLKHAEDGVLDLNKAAEIL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIRWKG 218
                        6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.0E-29150220IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467853.16E-17153216IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.6E-35153218IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.5E-24155218IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.68E-49229335No hitNo description
SuperFamilySSF1440744.97E-34231335No hitNo description
PfamPF164215.1E-34234333IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 480 aa     Download sequence    Send to blast
MSGNRAVNRS LQPTTTSGLQ QQQMLQSMRR QPPFSSMKPP FVPPDDYHRF SGGTTSNRGG  60
VIDEKAVEAI IVKSPLKRKS ETEDHEAESS DWAVNTGFTE VVNSPLRTPV SGKGTRVYNK  120
SKASKCNRSA PQTPISNIGS PSGTALTPAG TCRYDSSLGL LTKKFINLLK HAEDGVLDLN  180
KAAEILEVQK RRIYDITNVL EGIGLIEKKL KNRIRWKGLD DIRPGEADDN ATRLQTEVEK  240
LSMEERRLDN QIREMQERLR DLSEDENNQK WLFVTEEDIK GLPCFQNETL IAIKAPHGTT  300
LEVPDPDEAA DYPQRRYRIV LRSTMGPIDV YLVSQFEEKF EEVNGPDVPP SIPLPSTSGA  360
NDKHQEAAMP GEGSSRKAVQ QEGQDTNGMC TDPNNAQDFV GGIMKIVPSD VDSDADYWLL  420
SDAGVSITDM WRTDPGIEWG GVDALNTDDF LMADISTPRA QTPPSDIIEP PSAANLNRR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A6e-24148219174PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010262959.10.0PREDICTED: transcription factor E2FA-like
RefseqXP_019053996.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY01e-161E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A2G5CA000.0A0A2G5CA00_AQUCA; Uncharacterized protein
STRINGAquca_072_00025.10.0(Aquilegia coerulea)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-163E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]