PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Achn380101 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia
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Family | E2F/DP | ||||||||
Protein Properties | Length: 386aa MW: 43745.4 Da PI: 9.569 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 75.3 | 6.1e-24 | 20 | 85 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rkeksL+ll+++fl+l+ k +++ l+e+a++L +v +rRRiYDi+NVLe+++++++++kn+++wkg Achn380101 20 RKEKSLGLLCTNFLSLYDKDGVETIGLDEAATRL---EV--ERRRIYDIVNVLESVGVLARMAKNRYSWKG 85 79*****************999************...99..****************************98 PP | |||||||
2 | E2F_TDP | 74.2 | 1.4e-23 | 152 | 232 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 rkeksL+lltq+f+kl+ +s+ + ++l+++ak L+ + ++k+RR+YDi NVL+++n iek ++k+++rw g Achn380101 152 RKEKSLGLLTQNFIKLFLCSNVELISLDDAAKILLGDahdpsIRRTKVRRLYDISNVLSSMNFIEKihhpeTRKPAFRWLG 232 79***************************************97789*********************************87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 9.7E-26 | 18 | 86 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 2.0E-27 | 20 | 85 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.22E-15 | 20 | 83 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 8.4E-20 | 21 | 85 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 6.7E-23 | 148 | 233 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.8E-31 | 152 | 232 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 6.1E-18 | 153 | 232 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.45E-11 | 154 | 233 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 386 aa Download sequence Send to blast |
MAMPSSEPKE SGSRHFPYCR KEKSLGLLCT NFLSLYDKDG VETIGLDEAA TRLEVERRRI 60 YDIVNVLESV GVLARMAKNR YSWKGFRGIP QALQDLKEEG LRENYSTFEV NAKVSDDDED 120 EKVSISIASS QDDKINRSSV SSFSKASKTN NRKEKSLGLL TQNFIKLFLC SNVELISLDD 180 AAKILLGDAH DPSIRRTKVR RLYDISNVLS SMNFIEKIHH PETRKPAFRW LGIREKSENG 240 SENAFVLKES KKRVFGTEIT NTSFKRSKAL LPKDGYSNQM SKTQLQAHVK CEPMGNEVHK 300 SNLQQDSRQS SKGYRFGPFA PVSVSRAGAA EKNNAKQVHD WENLAATYRP EYHNQALRDL 360 FDHYVEAWKS WHSEVAGKNP IQLMS* |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 6e-43 | 20 | 224 | 4 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_028051660.1 | 0.0 | E2F transcription factor-like E2FE isoform X4 | ||||
Swissprot | Q8LSZ4 | 1e-124 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A2R6QGS3 | 0.0 | A0A2R6QGS3_ACTCH; E2F transcription factor-like | ||||
STRING | XP_009607525.1 | 1e-170 | (Nicotiana tomentosiformis) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Asterids | OGEA2522 | 24 | 57 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-124 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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