PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn363501

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

GRF

Protein Properties

Length: 546aa MW: 58823.7 Da PI: 9.3757

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn363501	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	73.4	2.6e-23	174	218	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+e grCrRtDGKkWRCsr++++++k+CErHl+rgr+rsrk++e Achn363501 174 DPELGRCRRTDGKKWRCSRDAVADHKYCERHLNRGRHRSRKPVEG 218 7999**************************************985 PP
2	QLQ	55.8	1.3e-19	113	148	2	37
QLQ 2 aFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 FT++Q+ +L++Q+l+yKy++an+PvP++Ll a+++ Achn363501 113 LFTPSQWVELEHQALIYKYIVANVPVPSNLLIALKN 148 6******************************99976 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	9.9E-11	112	148	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	21.503	113	148	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	5.9E-14	114	146	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	24.911	174	218	IPR014977	WRC domain
Pfam	PF08879	1.7E-19	175	217	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 546 aa Download sequence Send to blast
MKAAVVADGA VSDPETTKLN NNGSRFLKQG ISGSGRDDWR SSKVARTDDS ESPNTKLHLQ 60 GTPLLLRSDS LQQNMLSFSS PRSEFPFLSK NGGSAVETPY SYTINSGYGS RGLFTPSQWV 120 ELEHQALIYK YIVANVPVPS NLLIALKNSL HPYGLSGLSS RSYAPNTCFS GNTDPELGRC 180 RRTDGKKWRC SRDAVADHKY CERHLNRGRH RSRKPVEGQT GQAVTGSNPK VGSIACSTSA 240 SVMSSNGASN SLGITQYQFK GLQTCAEHPS ADMLVNRMQI PRGLSAVSPT TNLKSKGYPF 300 SIPKPHNPFE VSSNSGFGVV YSDSLLNPSQ KNSYMNSTDY NPILDFSNCE SDDQHPLRHF 360 IDQGPKDRPN RATIAWPDEL KSDWTQLSMS IPMAASDFSS ILSSSPQEKI ALSPLRPSHE 420 LNPIQMGLTV NNHFSDSTEK QKNQMPISWG SSMGGPLAEV LNSTSSAAGP CKKSALNLTT 480 RAWNGSPQLG SSPTGVLQKT MFVSLSNSSS GSSPRADKKQ SNGIGILGDD MLGSTLVSSF 540 SIPSL*

Sequence ? help Back to Top

Protein Sequence Length: 546 aa Download sequence Send to blast

MKAAVVADGA VSDPETTKLN NNGSRFLKQG ISGSGRDDWR SSKVARTDDS ESPNTKLHLQ  60
GTPLLLRSDS LQQNMLSFSS PRSEFPFLSK NGGSAVETPY SYTINSGYGS RGLFTPSQWV  120
ELEHQALIYK YIVANVPVPS NLLIALKNSL HPYGLSGLSS RSYAPNTCFS GNTDPELGRC  180
RRTDGKKWRC SRDAVADHKY CERHLNRGRH RSRKPVEGQT GQAVTGSNPK VGSIACSTSA  240
SVMSSNGASN SLGITQYQFK GLQTCAEHPS ADMLVNRMQI PRGLSAVSPT TNLKSKGYPF  300
SIPKPHNPFE VSSNSGFGVV YSDSLLNPSQ KNSYMNSTDY NPILDFSNCE SDDQHPLRHF  360
IDQGPKDRPN RATIAWPDEL KSDWTQLSMS IPMAASDFSS ILSSSPQEKI ALSPLRPSHE  420
LNPIQMGLTV NNHFSDSTEK QKNQMPISWG SSMGGPLAEV LNSTSSAAGP CKKSALNLTT  480
RAWNGSPQLG SSPTGVLQKT MFVSLSNSSS GSSPRADKKQ SNGIGILGDD MLGSTLVSSF  540
SIPSL*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:22419826, ECO:0000269\|PubMed:22751317}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:22419826}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028059566.1	0.0	growth-regulating factor 1-like isoform X2
Swissprot	O81001	9e-99	GRF1_ARATH; Growth-regulating factor 1
TrEMBL	A0A2R6RKW6	0.0	A0A2R6RKW6_ACTCH; Growth-regulating factor like
STRING	VIT_00s0494g00010.t01	0.0	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1688	23	57

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22840.1	1e-100	growth-regulating factor 1

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]