PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn198481

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

ERF

Protein Properties

Length: 490aa MW: 54669.7 Da PI: 4.6616

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn198481	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.4	8.6e-19	109	158	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa a++a ++k++g Achn198481 109 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAAIAYDAEARKIRG 158 69*****.******954...4***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	23.696	109	166	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.25E-22	109	168	IPR016177	DNA-binding domain
SMART	SM00380	7.4E-38	109	172	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	9.2E-32	109	168	IPR001471	AP2/ERF domain
CDD	cd00018	2.05E-32	109	167	No hit	No description
PRINTS	PR00367	5.7E-11	110	121	IPR001471	AP2/ERF domain
Pfam	PF00847	5.6E-11	110	158	IPR001471	AP2/ERF domain
PRINTS	PR00367	5.7E-11	132	148	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 490 aa Download sequence Send to blast
MCGGAIISDF IAPTRNRRLI ENLLWPSDVK KNHSNYHSKP LRSEIVDLDD DFEADFQDFK 60 DDTDAEDNDF KSFVFSASKS GVSDGSRSTK SVELNGQTEK TAKRKRKNQY RGIRQRPWGK 120 WAAEIRDPRK GVRVWLGTFN TAEEAAIAYD AEARKIRGRK AKVNFPDEAP PNAAKRAIKA 180 NTQKVLAKES INSVQPNLNQ NFNFPNNPEN DCYSMNFEEE KPLTGQFGYT EAYPVPGEVG 240 HKSSTPSAGA IPLYFNSDQG SNSFDCSDFE WGEYNTKTPD ISSVLSATIE CDEAQFVDNA 300 NPTEKLKTKL EDVGPVQENT VEKLSEELSA FESQMKFFQI PYLEANWDAS VDTFLNGDAT 360 QDGGSSMNLW TFDDFPSMMG GVFAVMDTVD KPVNLLSPLD GVLINLALGG YQDDIRRHSV 420 ANEHNEKCIT SFTIGHVRWQ KWVWMNSSAF RLVQEADSLG DWFCCNGLCC RSITKFGDSL 480 QDLAVGLAT*

Sequence ? help Back to Top

Protein Sequence Length: 490 aa Download sequence Send to blast

MCGGAIISDF IAPTRNRRLI ENLLWPSDVK KNHSNYHSKP LRSEIVDLDD DFEADFQDFK  60
DDTDAEDNDF KSFVFSASKS GVSDGSRSTK SVELNGQTEK TAKRKRKNQY RGIRQRPWGK  120
WAAEIRDPRK GVRVWLGTFN TAEEAAIAYD AEARKIRGRK AKVNFPDEAP PNAAKRAIKA  180
NTQKVLAKES INSVQPNLNQ NFNFPNNPEN DCYSMNFEEE KPLTGQFGYT EAYPVPGEVG  240
HKSSTPSAGA IPLYFNSDQG SNSFDCSDFE WGEYNTKTPD ISSVLSATIE CDEAQFVDNA  300
NPTEKLKTKL EDVGPVQENT VEKLSEELSA FESQMKFFQI PYLEANWDAS VDTFLNGDAT  360
QDGGSSMNLW TFDDFPSMMG GVFAVMDTVD KPVNLLSPLD GVLINLALGG YQDDIRRHSV  420
ANEHNEKCIT SFTIGHVRWQ KWVWMNSSAF RLVQEADSLG DWFCCNGLCC RSITKFGDSL  480
QDLAVGLAT*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	9e-22	109	166	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	GQ869856	0.0	GQ869856.1 Actinidia deliciosa ethylene response factor 5 (ERF5) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028064263.1	0.0	ethylene-responsive transcription factor RAP2-12-like
Swissprot	Q9SSA8	3e-78	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	D8VD32	0.0	D8VD32_ACTDE; Ethylene response factor 5
STRING	XP_009775920.1	1e-164	(Nicotiana sylvestris)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1446	24	66

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.2	3e-67	related to AP2 12

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]