PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn073211

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

E2F/DP

Protein Properties

Length: 363aa MW: 40278.1 Da PI: 4.6311

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn073211	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	25	3e-08	69	119	7	55
E2F_TDP 7 rlltqkflkllekseegivtlnevakeLvse....dvknkrRRiYDilNVLea 55 +llt+kf++l++++e+gi++ln++a++L +e ++ + RR+ D + V++a Achn073211 69 GLLTKKFINLIKHAEDGILDLNNAAETLEAEveklSM--EERRLDDRIRVMNA 119 589***********************776995555..9****9999988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	1.0E-5	69	120	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF144074	7.06E-27	94	217	No hit	No description
CDD	cd14660	1.97E-43	96	217	No hit	No description
Pfam	PF16421	3.0E-26	132	215	IPR032198	E2F transcription factor, CC-MB domain

Sequence ? help Back to Top
Protein Sequence Length: 363 aa Download sequence Send to blast
MAKMQLKRKS GTKYNEVGPS DWTSSPGCTD MANSPLRTPV SGKGGRVYGR SKVSKSNRSG 60 PQTPMSDAGL LTKKFINLIK HAEDGILDLN NAAETLEAEV EKLSMEERRL DDRIRVMNAA 120 TLRRLDLLIL PDCCREMQER LRDLSEDQNN QRWLFVTEED IKGLPCFQHE TLIAIKAPHG 180 TTLEVPDPDE AVDYPQRRYR IILRSTMGPI DVYLVSQFEE KFEDMNSVEP STSFPIASSS 240 GSNENPATEM ITVVSSGVEV EPQAQYSHRM SCDPNLSHDY PGGIRKIVPS DIDNDADYWL 300 LSDADVSITD MWKTDSTAGV EWDGVDVLHE EFGMADIGTS RPQTPPSRGI DVPSAAGNLK 360 QR*

Sequence ? help Back to Top

Protein Sequence Length: 363 aa Download sequence Send to blast

MAKMQLKRKS GTKYNEVGPS DWTSSPGCTD MANSPLRTPV SGKGGRVYGR SKVSKSNRSG  60
PQTPMSDAGL LTKKFINLIK HAEDGILDLN NAAETLEAEV EKLSMEERRL DDRIRVMNAA  120
TLRRLDLLIL PDCCREMQER LRDLSEDQNN QRWLFVTEED IKGLPCFQHE TLIAIKAPHG  180
TTLEVPDPDE AVDYPQRRYR IILRSTMGPI DVYLVSQFEE KFEDMNSVEP STSFPIASSS  240
GSNENPATEM ITVVSSGVEV EPQAQYSHRM SCDPNLSHDY PGGIRKIVPS DIDNDADYWL  300
LSDADVSITD MWKTDSTAGV EWDGVDVLHE EFGMADIGTS RPQTPPSRGI DVPSAAGNLK  360
QR*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5tuv_B	1e-13	96	217	13	111	Transcription factor E2F5
5tuv_E	1e-13	96	217	13	111	Transcription factor E2F5
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11889041, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:15377755, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:19662336}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_028074977.1	0.0	transcription factor E2FA
Swissprot	Q9FNY0	1e-93	E2FA_ARATH; Transcription factor E2FA
TrEMBL	A0A2R6Q416	0.0	A0A2R6Q416_ACTCH; Transcription factor E2FA like
STRING	XP_009349217.1	1e-161	(Pyrus x bretschneideri)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G36010.1	4e-96	E2F transcription factor 3

Publications ? help Back to Top
Magyar Z, et al. Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes. EMBO J., 2012. 31(6): p. 1480-93 [PMID:22307083]