PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn027081

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

MYB

Protein Properties

Length: 278aa MW: 31412.6 Da PI: 8.6507

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn027081	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	43.9	5.6e-14	8	53	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 +g+W +eEde l++ vk++G+++W++I ++ ++Rt+k+c++rw + Achn027081 8 KGPWKAEEDEVLIRHVKKYGPRDWSSIRSKGLLHRTGKSCRLRWVN 53 79***********************888779*********87 PP
2	Myb_DNA-binding	41.2	3.7e-13	64	103	3	44
SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHH CS Myb_DNA-binding 3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrw 44 ++++eE+ + +++ q+G++ W++Ia +++ gRt++++k++w Achn027081 64 KFSAEEERIAIELQGQFGNK-WARIATYLP-GRTDNDVKNFW 103 79****************.*****.********* PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.60	3.3E-21	3	56	IPR009057	Homeodomain-like
PROSITE profile	PS51294	22.092	3	59	IPR017930	Myb domain
SuperFamily	SSF46689	1.61E-28	6	103	IPR009057	Homeodomain-like
SMART	SM00717	1.2E-12	7	57	IPR001005	SANT/Myb domain
CDD	cd00167	2.03E-13	10	55	No hit	No description
Pfam	PF13921	1.9E-12	11	62	No hit	No description
Gene3D	G3DSA:1.10.10.60	4.3E-17	57	109	IPR009057	Homeodomain-like
PROSITE profile	PS51294	15.89	60	111	IPR017930	Myb domain
SMART	SM00717	7.2E-12	61	109	IPR001005	SANT/Myb domain
Pfam	PF00249	4.4E-11	64	103	IPR001005	SANT/Myb domain
CDD	cd00167	2.74E-10	64	103	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0048235	Biological Process	pollen sperm cell differentiation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 278 aa Download sequence Send to blast
MGDDQIRKGP WKAEEDEVLI RHVKKYGPRD WSSIRSKGLL HRTGKSCRLR WVNKLRPNLK 60 NGVKFSAEEE RIAIELQGQF GNKWARIATY LPGRTDNDVK NFWSSRQKRL ARLLQTPTPR 120 IASSKSHNRK QVSILHGDGP TNILAPKISS LTNEDSSCSF ISPNFLHHDQ NLLHLDFHSA 180 KENQILLFPS IPQVLQQPDF PRALGNEVST NFLDMFENFD ATDLGSLAQI PLVPPCFGPP 240 RGQFCQTESP VTPGGFFNDF PVDMFDPMDP IPSPSEW*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h8a_C	9e-28	5	109	24	126	MYB TRANSFORMING PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269\|PubMed:15618418, ECO:0000269\|PubMed:15694308, ECO:0000269\|PubMed:19300502, ECO:0000269\|PubMed:21285328, ECO:0000269\|PubMed:24876252}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269\|PubMed:21441434, ECO:0000269\|PubMed:25057814}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_022897300.1	2e-93	transcription factor DUO1-like
Refseq	XP_027106540.1	2e-93	transcription factor DUO1-like
Refseq	XP_027112927.1	2e-93	transcription factor DUO1-like
Refseq	XP_027160096.1	2e-93	transcription factor DUO1
Swissprot	A0A178VEK7	1e-70	DUO1_ARATH; Transcription factor DUO1
TrEMBL	A0A2R6QPI0	0.0	A0A2R6QPI0_ACTCH; Transcription factor GAMYB like
STRING	VIT_15s0021g02040.t01	6e-92	(Vitis vinifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA4207	23	42

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G60460.1	6e-69	MYB family protein

Publications ? help Back to Top
Zheng B,He H,Zheng Y,Wu W,McCormick S An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana. PLoS Genet., 2014. 10(7): p. e1004421 [PMID:25057814] Peters B, et al. A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter. Plant Physiol., 2017. 173(1): p. 280-293 [PMID:27624837] Zheng Z, et al. Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy. Plant Physiol., 2017. 174(3): p. 1764-1778 [PMID:28515145]