PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA5G00105
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family ARF
Protein Properties Length: 897aa    MW: 99986.2 Da    PI: 6.7416
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA5G00105genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B331.53.1e-102522955499
                EETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
         B3  54 kksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                ++++r++l++GW+ Fv++++L +gD ++F   + +++el+v+v+r+
  AA5G00105 252 GQPRRHLLQSGWSVFVSSKRLVAGDAFIFL--RGENGELRVGVRRA 295
                57899*************************..449999*****996 PP
2Auxin_resp120.11.8e-39320402183
  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalkvkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 
                 a+ha+st+++F+v+Y+Pr+s+seF+v+++++++++k+++++GmRfkm+fe+e+++e+r++Gt+vg++d+dp+rW +SkWrsLk
   AA5G00105 320 AWHAISTGTMFTVYYKPRTSPSEFIVPFDQYMESVKNNYTIGMRFKMRFEGEEAPEQRFTGTIVGIEDSDPTRWAKSKWRSLK 402
                 89*******************************************************************************96 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.40.330.106.9E-37159220IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019361.44E-23160222IPR015300DNA-binding pseudobarrel domain
CDDcd100174.33E-15161294No hitNo description
PROSITE profilePS508639.305163296IPR003340B3 DNA binding domain
SMARTSM010191.9E-8163296IPR003340B3 DNA binding domain
Gene3DG3DSA:2.40.330.106.9E-37252309IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.09E-10252323IPR015300DNA-binding pseudobarrel domain
PfamPF023622.0E-7252295IPR003340B3 DNA binding domain
PfamPF065071.3E-36320402IPR010525Auxin response factor
PfamPF023096.0E-5753807IPR033389AUX/IAA domain
SuperFamilySSF542771.13E-11769848No hitNo description
PROSITE profilePS5174525.747771855IPR000270PB1 domain
PfamPF023098.2E-7817855IPR033389AUX/IAA domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009737Biological Processresponse to abscisic acid
GO:0009911Biological Processpositive regulation of flower development
GO:0010047Biological Processfruit dehiscence
GO:0010150Biological Processleaf senescence
GO:0010227Biological Processfloral organ abscission
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0048481Biological Processplant ovule development
GO:0005634Cellular Componentnucleus
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 897 aa     Download sequence    Send to blast
MVSSEISMKR DRGGENFSSG YSDAKEARNV SISGEGQKSH YSRSITAERT VDPETALYRE  60
LWHACAGPLV TVPRKDDRVF YFPQGHIEQV EASTNQEAEQ QMPLYDLPSK LLCRVINVDL  120
KAEADTDEVY AQITLLPEAN QDENAIEKEA PPPPPPRFQV HSFCKTLTAS DTSTHGGFSV  180
LRRHADECLP PLDMSRQPPT QELVAKDLHS NEWRFRHIFR GTYECPHMVS FGAVSVPCFL  240
SAIDVCVNVI PGQPRRHLLQ SGWSVFVSSK RLVAGDAFIF LRGENGELRV GVRRAMRQQG  300
NVPSSVISSH SMHLGVLATA WHAISTGTMF TVYYKPRTSP SEFIVPFDQY MESVKNNYTI  360
GMRFKMRFEG EEAPEQRFTG TIVGIEDSDP TRWAKSKWRS LKVRWDETSS IPRPERVSPW  420
KIEPALAPPA LSPVPMPRPK RPRPNIAPSS PDSSVLAREG NVFPFIAVHV LVRREGSSKA  480
NMDPLPASGL SRVLQGQEYS TLRTKLTESV ESDVPESSVV WQSSADDDKV DVVSVSRRYG  540
AENWMSSGRH EPTYTDLLSG FGANVDPSHG QRLPFYDHSL SPSVPTKKIS NDQDGKFDYI  600
SNQWQMMHSG LSLKLSESPK VPVAASNVKY GEYPVLHSLT TENSSGNWPI RPRALNYFED  660
MAHVQAQAQA QSQAQAREHA TKRPVMMLQE ETGKTRDGNC RIFGIPLVTG TDSTMPQRNN  720
VNESAGLTQI ASPKVQDLSE QSKASKSGNE PREQSKQFQT KEAQGKTNSN RSCTKVHKQG  780
SALGRSVDLS KFNNYEELIR ELDTLFEFNG ELMAPKKDWL IVYTDDEGDM MLVGDDPWQE  840
FCCMVRKIVI YTKEEVRKIK PGSLSCRSDE DAVVGEGSDT KDAKSASNPS LSSAGNS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldv_A1e-1745642418354Auxin response factor 1
4ldw_A1e-1745642418354Auxin response factor 1
4ldw_B1e-1745642418354Auxin response factor 1
4ldx_A1e-1745642418354Auxin response factor 1
4ldx_B1e-1745642418354Auxin response factor 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1439443KRPRP
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Promotes flowering, stamen development, floral organ abscission and fruit dehiscence. Functions independently of ethylene and cytokinin response pathways. May act as a repressor of cell division and organ growth. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:15960614, ECO:0000269|PubMed:16176952, ECO:0000269|PubMed:16339187}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00574DAPTransfer from AT5G62000Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA5G00105
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001330603.10.0auxin response factor 2
RefseqNP_201006.20.0auxin response factor 2
RefseqNP_851244.10.0auxin response factor 2
RefseqNP_974980.10.0auxin response factor 2
SwissprotQ94JM30.0ARFB_ARATH; Auxin response factor 2
TrEMBLA0A178UUC30.0A0A178UUC3_ARATH; Auxin response factor
STRINGAT5G62000.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM53482647
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62000.30.0auxin response factor 2
Publications ? help Back to Top
  1. Chao WS,Doğramaci M,Foley ME,Horvath DP,Anderson JV
    Selection and validation of endogenous reference genes for qRT-PCR analysis in leafy spurge (Euphorbia esula).
    PLoS ONE, 2012. 7(8): p. e42839
    [PMID:22916167]
  2. Ozerova LV,Krasnikova MS,Troitsky AV,Solovyev AG,Morozov SY
    TAS3 Genes for small ta-siARF RNAs in plants belonging to subtribe Senecioninae: occurrence of prematurely terminated RNA precursors.
    Mol. Gen. Mikrobiol. Virusol., 2013.
    [PMID:24003511]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Lyons R, et al.
    Fusarium oxysporum triggers tissue-specific transcriptional reprogramming in Arabidopsis thaliana.
    PLoS ONE, 2015. 10(4): p. e0121902
    [PMID:25849296]
  5. Roodbarkelari F,Du F,Truernit E,Laux T
    ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response.
    BMC Biol., 2015. 13: p. 74
    [PMID:26358077]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Zhao S,Zhang ML,Ma TL,Wang Y
    Phosphorylation of ARF2 Relieves Its Repression of Transcription of the K+ Transporter Gene HAK5 in Response to Low Potassium Stress.
    Plant Cell, 2016. 28(12): p. 3005-3019
    [PMID:27895227]
  8. Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z
    ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis .
    J Integr Plant Biol, 2017. 59(1): p. 30-43
    [PMID:28074634]
  9. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  10. Sanz-Fernández M, et al.
    Screening Arabidopsis mutants in genes useful for phytoremediation.
    J. Hazard. Mater., 2017. 335: p. 143-151
    [PMID:28441590]
  11. Zhang M,Hu X,Zhu M,Xu M,Wang L
    Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    Sci Rep, 2017. 7(1): p. 1395
    [PMID:28469131]
  12. Guan C, et al.
    Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
    Curr. Biol., 2017. 27(19): p. 2940-2950.e4
    [PMID:28943086]
  13. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  14. Sarkar Das S, et al.
    Expression dynamics of miRNAs and their targets in seed germination conditions reveals miRNA-ta-siRNA crosstalk as regulator of seed germination.
    Sci Rep, 2018. 8(1): p. 1233
    [PMID:29352229]