PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA3G00002
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family MIKC_MADS
Protein Properties Length: 233aa    MW: 26886.9 Da    PI: 9.9194
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA3G00002genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF93.31.2e-29959151
               S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
     SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
               krien + rqvtfskRrng+lKKA+ELSvLC+aeva++ifs++gklye+ss
  AA3G00002  9 KRIENATSRQVTFSKRRNGLLKKAFELSVLCEAEVALVIFSPRGKLYEFSS 59
               79***********************************************96 PP
2K-box805.9e-2782172999
      K-box   9 leeakaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkle 99 
                + ++++++ + e   L k+ie+L+ ++R+++Ge+L++ s++eLqqLe+qL++sl+kiR+kK++ll+e+ie+l++ke++l  enk L++k++
  AA3G00002  82 KGDENSQKAKDETYGLTKKIEQLEISKRKMMGEGLDESSIEELQQLENQLDRSLSKIRAKKYQLLREEIEKLKQKERNLIAENKLLKEKFM 172
                568899**********************************************************************************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006631.427161IPR002100Transcription factor, MADS-box
SMARTSM004327.4E-40160IPR002100Transcription factor, MADS-box
PRINTSPR004043.7E-30323IPR002100Transcription factor, MADS-box
SuperFamilySSF554553.27E-31374IPR002100Transcription factor, MADS-box
CDDcd002655.82E-35372No hitNo description
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003194.5E-261057IPR002100Transcription factor, MADS-box
PRINTSPR004043.7E-302338IPR002100Transcription factor, MADS-box
PRINTSPR004043.7E-303859IPR002100Transcription factor, MADS-box
PfamPF014862.2E-2584171IPR002487Transcription factor, K-box
PROSITE profilePS5129715.30187180IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010076Biological Processmaintenance of floral meristem identity
GO:0010082Biological Processregulation of root meristem growth
GO:0010228Biological Processvegetative to reproductive phase transition of meristem
GO:2000012Biological Processregulation of auxin polar transport
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 233 aa     Download sequence    Send to blast
MVRGKTEMKR IENATSRQVT FSKRRNGLLK KAFELSVLCE AEVALVIFSP RGKLYEFSSS  60
SSITKTIERY QKRIKELGPN YKGDENSQKA KDETYGLTKK IEQLEISKRK MMGEGLDESS  120
IEELQQLENQ LDRSLSKIRA KKYQLLREEI EKLKQKERNL IAENKLLKEK FMILMKYEME  180
GGRGMITSSS SSLSSTSSEE GKIISDNEME VVTDLFIGPP DHTRHSKRLF LPY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A2e-15160160MEF2C
5f28_B2e-15160160MEF2C
5f28_C2e-15160160MEF2C
5f28_D2e-15160160MEF2C
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that regulates root development by controlling meristem size and patterning of the root apical meristem. Regulates auxin transport and gradients in the root meristematic cells via direct regulation of the auxin efflux carrier PIN1 and PIN4 gene expression. Binds specifically to the CArG-box DNA sequences in the promoter regions of PIN1 and PIN4 genes (PubMed:24121311). Involved in the regulation of shoot apical meristem (SAM) cell identities and transitions. Promotes flowering transition and participates in flower meristem maintenance and determinacy. Positively regulates TFL1 and WUS expression. Binds directly to the TFL1 regulatory sequences (PubMed:25636918). {ECO:0000269|PubMed:24121311}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA3G00002
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By auxin. {ECO:0000269|PubMed:24121311}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010455600.11e-113PREDICTED: agamous-like MADS-box protein AGL14 isoform X1
SwissprotQ388381e-105AGL14_ARATH; Agamous-like MADS-box protein AGL14
TrEMBLA0A1J3D0C61e-111A0A1J3D0C6_NOCCA; Agamous-like MADS-box protein AGL14
STRINGXP_010455600.11e-112(Camelina sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM7828413
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G11880.11e-105AGAMOUS-like 14
Publications ? help Back to Top
  1. Zimmermann P,Hirsch-Hoffmann M,Hennig L,Gruissem W
    GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox.
    Plant Physiol., 2004. 136(1): p. 2621-32
    [PMID:15375207]
  2. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  3. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]