PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA31G00615
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family HD-ZIP
Protein Properties Length: 735aa    MW: 80366.5 Da    PI: 6.471
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA31G00615genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.53e-203085156
                TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
    Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                +++ +++t++q+++Le+ F+++++p++++r++L+++lgL  rq+k+WFqNrR++ k
  AA31G00615 30 KKRYHRHTAHQIQRLESSFKECPHPDEKQRTQLSRELGLAPRQIKFWFQNRRTQLK 85
                688999**********************************************9877 PP
2START159.33e-502304502206
                 HHHHHHHHHHHHHHHC-TT-EEEE...EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEECT CS
       START   2 laeeaaqelvkkalaeepgWvkss...esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddkeqWdetla....kaetleviss 87 
                 +a+ a++el+++ + +ep+W +     + +n  ++  +f++s +       ++ea+r sg+v+m++++lv  ++d + +W e ++    + +tl+ +ss
  AA31G00615 230 IALNALDELLRLLQTNEPLWNRADgsrDVLNLGTYENIFSRSSSrgknhnLRVEASRSSGIVFMNAMTLVDMFMDCA-KWAELFPsivaASKTLALVSS 327
                 678999***************999888999999999999998889999*9***************************.*******99999********* PP

                 T......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.H CS
       START  88 g......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.h 178
                 g      gal+l + el +lsplv+ R+f  +Ry++q ++g+wv+v vS d +q+++ +    R+ +lpSg+li+++sng+skvtwvehv+ +++ p h
  AA31G00615 328 GiggtheGALHLLYEELEVLSPLVAtREFCELRYCQQIEQGTWVVVNVSYDLPQFVS-H---SRSYRLPSGCLIQDMSNGYSKVTWVEHVEIEEKEPvH 422
                 ********************************************************9.4...55556******************************** PP

                 HHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
       START 179 wllrslvksglaegaktwvatlqrqcek 206
                 +l+r lv+sg+a+ga +w+ tlqr ce+
  AA31G00615 423 ELYRELVHSGIAFGAERWLTTLQRTCER 450
                 **************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.72E-20787IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.606.2E-231581IPR009057Homeodomain-like
PROSITE profilePS5007118.1722787IPR001356Homeobox domain
SMARTSM003892.4E-192891IPR001356Homeobox domain
CDDcd000863.19E-193088No hitNo description
PfamPF000469.6E-183085IPR001356Homeobox domain
PROSITE patternPS0002706285IPR017970Homeobox, conserved site
PROSITE profilePS5084851.974220453IPR002913START domain
SuperFamilySSF559611.54E-34221452No hitNo description
CDDcd088758.16E-104224449No hitNo description
SMARTSM002341.6E-41229450IPR002913START domain
PfamPF018522.8E-43230450IPR002913START domain
Gene3DG3DSA:3.30.530.201.3E-7230433IPR023393START-like domain
SuperFamilySSF559611.65E-17471646No hitNo description
SuperFamilySSF559611.65E-17677716No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 735 aa     Download sequence    Send to blast
MDFVVGGSGS GSGGDGGSQQ HGGSETERKK KRYHRHTAHQ IQRLESSFKE CPHPDEKQRT  60
QLSRELGLAP RQIKFWFQNR RTQLKAQHER ADNCALKAEN DKIRCENIAI REALKHAICP  120
NCGGPPISED PYYDEQKLRI ENAHLREELE RMSSIASKYM GRPMSQISTL HPMHMSPLDL  180
SMTSLGSGQV MTGPSLDFDL LPGSSMAVPN LPSQPNFTLS DMDKPLMTDI ALNALDELLR  240
LLQTNEPLWN RADGSRDVLN LGTYENIFSR SSSRGKNHNL RVEASRSSGI VFMNAMTLVD  300
MFMDCAKWAE LFPSIVAASK TLALVSSGIG GTHEGALHLL YEELEVLSPL VATREFCELR  360
YCQQIEQGTW VVVNVSYDLP QFVSHSRSYR LPSGCLIQDM SNGYSKVTWV EHVEIEEKEP  420
VHELYRELVH SGIAFGAERW LTTLQRTCER FASLLVPAAS SRDPGEVITS PEGKRSMMRL  480
AQRMVSNYCL SVGTSKNSRA TIVADLNEVE VRVTAHKSPE PNGTVLCAAT TFWLPISPQN  540
VFNFLKDERT RPQWDVLSNG NTVQEVAHIS NGSHTGNCIS VLRAFNASQS NMLILQESSI  600
DSSGALVVYS PVDLAGLNIA MSGEDPSYIP LLSSGFTISP DGNSNGNSSN STITSTEQGG  660
GASTSSGRSS SSSSSSGSLI TVGFQIMVSN LPSAKLKMES VDTVNNLIGT TVHQIKTALN  720
SPATTTTATT TITTA
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA31G00615
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010428260.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLR0I7H50.0R0I7H5_9BRAS; Uncharacterized protein
STRINGBostr.10273s0021.1.p0.0(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM30042665
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]