PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aan015138
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia
Family ARR-B
Protein Properties Length: 226aa    MW: 25586.6 Da    PI: 6.7228
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-183a-Artemisia_annua-55828PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like66.93.6e-21163217155
    G2-like   1 kprlrWtpeLHer.FveaveqLGGsekAtPktilelmkvkgLtlehvkSHLQkYRl 55 
                kpr++W+ e  ++  ++ v+qL G++kA+Pk+ilelm+v+gLt+e+v+SHLQkYRl
  Aan015138 163 KPRVVWSVEXPSAvLLQPVNQL-GIDKAVPKKILELMNVPGLTRENVASHLQKYRL 217
                79*****9997652789*****.********************************8 PP

2Response_reg63.69.7e-2239616109
                   HHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTESEEEESS--HHHHHH CS
  Response_reg  16 qalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGakdflsKpfdpeelvk 109
                   ++l++ +y ev+ +  +e al  l+e++  +D+++ D+ mp+mdG++ll++i  e  +lp+i+++a ++++ + + +  Ga d+l Kp+ +e+l++
     Aan015138   3 KMLRNCNY-EVTKCNRAEVALSHLRENKngFDVVISDVHMPDMDGFKLLEHIGLEM-DLPVIMMSADDSKNVVMKGVTHGACDYLIKPVRIEALRN 96 
                   67888899.***************999999**********************6654.8***********************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0363928.5E-1261226IPR017053Response regulator B-type, plant
SMARTSM004481.2E-12198IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011034.7941102IPR001789Signal transduction response regulator, receiver domain
Gene3DG3DSA:3.40.50.23001.2E-342121No hitNo description
CDDcd001563.38E-222101No hitNo description
SuperFamilySSF521722.28E-282109IPR011006CheY-like superfamily
PfamPF000729.8E-19396IPR001789Signal transduction response regulator, receiver domain
SuperFamilySSF466891.08E-14161221IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.3E-22162222IPR009057Homeodomain-like
TIGRFAMsTIGR015578.5E-19163217IPR006447Myb domain, plants
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 226 aa     Download sequence    Send to blast
XEKMLRNCNY EVTKCNRAEV ALSHLRENKN GFDVVISDVH MPDMDGFKLL EHIGLEMDLP  60
VIMMSADDSK NVVMKGVTHG ACDYLIKPVR IEALRNIWQH VVRKKKHEWK EVEPSPSADE  120
QKPPEEPDYS SSANEGHNGK TQKGGKNEDD DADDRDDSSS LKKPRVVWSV EXPSAVLLQP  180
VNQLGIDKAV PKKILELMNV PGLTRENVAS HLQKYRLYLR RLSGSQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A3e-17159223164ARR10-B
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Detected in the whole plant. Predominantly expressed in pollen. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:15173562, ECO:0000269|PubMed:9891419}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Involved in the expression of nuclear genes for components of mitochondrial complex I. Promotes cytokinin-mediated leaf longevity. Involved in the ethylene signaling pathway in an ETR1-dependent manner and in the cytokinin signaling pathway. {ECO:0000269|PubMed:11370868, ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:15282545, ECO:0000269|PubMed:16407152}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023766807.11e-133two-component response regulator ARR2-like isoform X3
SwissprotQ9ZWJ91e-105ARR2_ARATH; Two-component response regulator ARR2
TrEMBLA0A2U1Q6581e-133A0A2U1Q658_ARTAN; Two-component response regulator
STRINGXP_009591694.11e-116(Nicotiana tomentosiformis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16857.14e-99response regulator 1
Publications ? help Back to Top
  1. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  2. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  3. Takahashi N,Umeda M
    Cytokinins promote onset of endoreplication by controlling cell cycle machinery.
    Plant Signal Behav, 2014. 9(8): p. e29396
    [PMID:25763620]
  4. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  5. Arnaud D, et al.
    Cytokinin-Mediated Regulation of Reactive Oxygen Species Homeostasis Modulates Stomatal Immunity in Arabidopsis.
    Plant Cell, 2017. 29(3): p. 543-559
    [PMID:28254779]
  6. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  7. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  8. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  9. Takatsuka H,Higaki T,Umeda M
    Actin Reorganization Triggers Rapid Cell Elongation in Roots.
    Plant Physiol., 2018. 178(3): p. 1130-1141
    [PMID:30185441]