PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aan013647
Organism
Artemisia annua
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia
Family ERF
Protein Properties Length: 286aa    MW: 32143.1 Da    PI: 5.4691
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Aan#S55195887PU_unrefUnigeneView CDS
PUT-183a-Artemisia_annua-80437PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP261.51.9e-19105154255
        AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                +y+G+r+++ +g+W+AeIrdp++     r++lg++ taeeAa+a++a + +++g
  Aan013647 105 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTYNTAEEAARAYDAEAIRIRG 154
                69*******.**********954...4**********************99997 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.101.1E-31105163IPR001471AP2/ERF domain
SMARTSM003806.6E-37105168IPR001471AP2/ERF domain
PROSITE profilePS5103224.157105162IPR001471AP2/ERF domain
SuperFamilySSF541713.4E-22105163IPR016177DNA-binding domain
CDDcd000181.94E-32105163No hitNo description
PfamPF008471.1E-12106154IPR001471AP2/ERF domain
PRINTSPR003671.5E-11106117IPR001471AP2/ERF domain
PRINTSPR003671.5E-11128144IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 286 aa     Download sequence    Send to blast
MCGGAILSDI IAPNRSRRLT SADLLWNTDN NSYFSSKANN VSDDADDDDF EADFQGFKDH  60
HDKPSFVFSS KHPSATATLH RGSRSVKSDD QADERSGSSR KRKNQYRGIR QRPWGKWAAE  120
IRDPRKGVRV WLGTYNTAEE AARAYDAEAI RIRGDKAKVN FPAKASPTKP KQQKQAPKVN  180
HTDNSEFPGS FEFVEEKPQL FHFSPNEGSN SFDCSEFPWG ENCPKTPEIT SLLSELDEAT  240
FMEEANPAKK PKIESVNLVS DCEISDDDLF FKMPFLQGAW DTSSVX
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A3e-21105164262ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A3e-21105166567ATERF1
3gcc_A3e-21105166567ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Aan.46110.0trichome
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Constitutive in flowers, leaves, stems, and roots. {ECO:0000269|PubMed:20357136, ECO:0000269|PubMed:9192694}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in carotenoid biosynthesis regulation. Binds to the 5'-ATCTA-3' element present in the promoter of phytoene synthase (PSY) and phytoene desaturase (PDS). Involved in ethylene response and resistance to necrotrophic pathogens. Acts as a downstream regulator in the ethylene signaling pathway. Partially redundant with RAP2-12. {ECO:0000269|PubMed:17873090, ECO:0000269|PubMed:20357136, ECO:0000269|PubMed:22530619}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by darkness, ethylene and Botrytis cinerea. {ECO:0000269|PubMed:20357136, ECO:0000269|PubMed:22530619}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024969283.11e-126ethylene-responsive transcription factor RAP2-2-like
SwissprotQ9LUM45e-53RAP22_ARATH; Ethylene-responsive transcription factor RAP2-2
TrEMBLA0A103YB321e-125A0A103YB32_CYNCS; AP2/ERF domain-containing protein
STRINGMigut.I01124.1.p2e-80(Erythranthe guttata)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G14230.33e-51related to AP2 2
Publications ? help Back to Top
  1. Haas BJ, et al.
    Full-length messenger RNA sequences greatly improve genome annotation.
    Genome Biol., 2002. 3(6): p. RESEARCH0029
    [PMID:12093376]
  2. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  3. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  4. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  5. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]