PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan013098

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

WRKY

Protein Properties

Length: 482aa MW: 52034.2 Da PI: 8.1446

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S41950851	PU_unref	Unigene	View CDS
PUT-183a-Artemisia_annua-107498	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	95.6	3.5e-30	143	202	1	59
---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 ++Dg++WrKYGqK kg+++pr+YYrCt + +Cpv+k+v+r+ +d +++++tYeg+Hnh+ Aan013098 143 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVSpTCPVRKQVQRCPQDMSILITTYEGTHNHP 202 58************************999**************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	1.4E-31	128	204	IPR003657	WRKY domain
SuperFamily	SSF118290	4.84E-27	135	204	IPR003657	WRKY domain
PROSITE profile	PS50811	28.472	138	204	IPR003657	WRKY domain
SMART	SM00774	6.0E-36	143	203	IPR003657	WRKY domain
Pfam	PF03106	1.0E-26	144	202	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 482 aa Download sequence Send to blast
XIIHNQQQET PTTINANAIK QNEEPQINDE SELVSLTLGR TSSMDIVKKD KRSTTPPTKS 60 AEGLDLGLEC GKFEISSTTQ AESSINLSPD NSLEEAKDEA GETWTPQKPP TPKRSGDDQE 120 VSQQNPVKKT RVSVRVRCDT PTMNDGCQWR KYGQKIAKGN PCPRAYYRCT VSPTCPVRKQ 180 VQRCPQDMSI LITTYEGTHN HPLPVSATAM ASTTSAAASM LTSGSSTSGS NSNPNPSTSS 240 HGLDFYLNEH SKLKPIYLPH SSMSPSPSCP TVTLDLTSNT LSTSSPYNYR STPMNTTFPP 300 RYSTTNLNFS SLESNALPLA WSNGTLNYGK SQIGSLNFGS TQPQENIYHS YMQNKNLMAT 360 TSNTNQHSLQ PDTIEAATKA ITSNPNFQSV LQAALKSIIG GGAMGGQVGD DRSSQNVKVG 420 DTFPVFSSFP STSNTNKCSS TFFNKSVATT AMNSQPTGSN SLPFSSSRSK STSPETSRDH 480 VV

Sequence ? help Back to Top

Protein Sequence Length: 482 aa Download sequence Send to blast

XIIHNQQQET PTTINANAIK QNEEPQINDE SELVSLTLGR TSSMDIVKKD KRSTTPPTKS  60
AEGLDLGLEC GKFEISSTTQ AESSINLSPD NSLEEAKDEA GETWTPQKPP TPKRSGDDQE  120
VSQQNPVKKT RVSVRVRCDT PTMNDGCQWR KYGQKIAKGN PCPRAYYRCT VSPTCPVRKQ  180
VQRCPQDMSI LITTYEGTHN HPLPVSATAM ASTTSAAASM LTSGSSTSGS NSNPNPSTSS  240
HGLDFYLNEH SKLKPIYLPH SSMSPSPSCP TVTLDLTSNT LSTSSPYNYR STPMNTTFPP  300
RYSTTNLNFS SLESNALPLA WSNGTLNYGK SQIGSLNFGS TQPQENIYHS YMQNKNLMAT  360
TSNTNQHSLQ PDTIEAATKA ITSNPNFQSV LQAALKSIIG GGAMGGQVGD DRSSQNVKVG  420
DTFPVFSSFP STSNTNKCSS TFFNKSVATT AMNSQPTGSN SLPFSSSRSK STSPETSRDH  480
VV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	3e-21	130	204	1	74	WRKY transcription factor 1
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, trichomes and fruits. {ECO:0000269\|PubMed:24884371}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269\|PubMed:20409007, ECO:0000269\|PubMed:24884371}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269\|PubMed:20409007}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023744175.1	0.0	probable WRKY transcription factor 61 isoform X1
Refseq	XP_023744176.1	0.0	probable WRKY transcription factor 61 isoform X2
Swissprot	A0A3Q7GFB5	1e-109	WK72A_SOLLC; WRKY transcription factor 72A
TrEMBL	A0A2U1KRY9	0.0	A0A2U1KRY9_ARTAN; WRKY DNA-binding protein 72
STRING	XP_010256554.1	1e-125	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G15130.1	3e-53	WRKY DNA-binding protein 72

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Spyropoulou EA,Haring MA,Schuurink RC RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters. BMC Genomics, 2014. 15: p. 402 [PMID:24884371]