PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Aan006769 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia
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Family | AP2 | ||||||||
Protein Properties | Length: 269aa MW: 29970.2 Da PI: 9.4336 | ||||||||
Description | AP2 family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | AP2 | 55.5 | 1.4e-17 | 56 | 105 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV++++++grW+++I+d + k+++lg f+ta Aa+a+++a+ k++g Aan006769 56 SQYRGVTFYRRTGRWESHIWD------CgKQVYLGGFDTAHAAARAYDRAAIKFRG 105 78*******************......55************************998 PP | |||||||
2 | AP2 | 44.2 | 4.8e-14 | 148 | 198 | 1 | 55 |
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 s+y+GV+ +k grW+A+ + +k+++lg f+t+ eAa+a+++a+ k +g Aan006769 148 SKYRGVTLHK-CGRWEARMGQF--L-GKKYVYLGLFDTEVEAARAYDKAAIKCNG 198 89********.7******5553..2.26**********99**********99776 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Pfam | PF00847 | 9.6E-10 | 56 | 105 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 3.14E-16 | 56 | 114 | IPR016177 | DNA-binding domain |
Gene3D | G3DSA:3.30.730.10 | 1.2E-17 | 57 | 113 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 17.649 | 57 | 113 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 1.3E-31 | 57 | 119 | IPR001471 | AP2/ERF domain |
Pfam | PF00847 | 1.3E-9 | 148 | 198 | IPR001471 | AP2/ERF domain |
SuperFamily | SSF54171 | 1.83E-17 | 148 | 208 | IPR016177 | DNA-binding domain |
CDD | cd00018 | 1.14E-24 | 148 | 208 | No hit | No description |
Gene3D | G3DSA:3.30.730.10 | 5.5E-17 | 149 | 207 | IPR001471 | AP2/ERF domain |
SMART | SM00380 | 1.3E-30 | 149 | 212 | IPR001471 | AP2/ERF domain |
PROSITE profile | PS51032 | 15.369 | 149 | 206 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 1.8E-6 | 150 | 161 | IPR001471 | AP2/ERF domain |
PRINTS | PR00367 | 1.8E-6 | 188 | 208 | IPR001471 | AP2/ERF domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 269 aa Download sequence Send to blast |
SMMQPPAAHW FGVKFSHQSS SSNGVAGDGF VGKSTTAAVI AQPLKKSRRG PRSRSSQYRG 60 VTFYRRTGRW ESHIWDCGKQ VYLGGFDTAH AAARAYDRAA IKFRGMEADI NFNLEDYEED 120 LKQMSNLTKE EFVHVLRRQS TGFPRGSSKY RGVTLHKCGR WEARMGQFLG KKYVYLGLFD 180 TEVEAARAYD KAAIKCNGKA AVTNFDSSIY ENDLNLTEGS SDNNNNDNVS SDHDLDLSLG 240 GGSMPSNMKN NGEHGRFVRD RHSDSIQLG |
Expression -- Description ? help Back to Top | ||||||
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Source | Description | |||||
Uniprot | DEVELOPMENTAL STAGE: It is detectable at low levels throughout the shoot apex and at enhanced levels in the inflorescence meristem, young floral buds and throughout the early stages of flower development and organogenesis. During floral organ differentiation it becomes spatially restricted to specific organ, tissue and cell types within the flower. | |||||
Uniprot | TISSUE SPECIFICITY: Sepals, petals, stamens, carpels, developing ovules, inflorescence stem, leaf and stem. |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Probable transcriptional activator that promotes early floral meristem identity (PubMed:7919989). Is required subsequently for the transition of an inflorescence meristem into a floral meristem (PubMed:1675158). Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes (PubMed:1675158, PubMed:23034631). Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors like LEUNIG and SEUSS (PubMed:1675158). Directly represses AGAMOUS by recruiting the transcriptional corepressor TOPLESS and the histone deacetylase HDA19 (PubMed:23034631). It is also required during seed development (PubMed:1675158). {ECO:0000269|PubMed:1675158, ECO:0000269|PubMed:23034631, ECO:0000269|PubMed:7919989}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Negatively regulated by the C class floral homeotic protein AGAMOUS in stamens and carpels. MicroRNA 172 (miRNA172) negatively regulates APETALA2 at the translational level and may modulate its expression pattern. Seems not to be influenced by jasmonate and Alternaria brassicicola. {ECO:0000269|PubMed:12805630, ECO:0000269|PubMed:12893888, ECO:0000269|PubMed:14555699}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_021998113.1 | 1e-145 | floral homeotic protein APETALA 2-like | ||||
Swissprot | P47927 | 1e-114 | AP2_ARATH; Floral homeotic protein APETALA 2 | ||||
TrEMBL | A0A251T3W1 | 1e-144 | A0A251T3W1_HELAN; Putative AP2-like ethylene-responsive transcription factor | ||||
STRING | XP_004509117.1 | 1e-120 | (Cicer arietinum) |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G36920.2 | 1e-110 | AP2 family protein |