PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan004280

Common Name

ERF3

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

ERF

Protein Properties

Length: 193aa MW: 22144 Da PI: 5.7541

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S55209402	PU_ref	Unigene	View CDS
PUT-183a-Artemisia_annua-44134	PU_unref	plantGDB	View CDS
PUT-183a-Artemisia_annua-44135	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.4	8.7e-19	53	102	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GVr ++ +g+++AeIrd + ng r++lg+f+taeeAa a+++a+ + +g Aan004280 53 YRGVRKRP-WGKFAAEIRDSTRNG--VRVWLGTFDTAEEAALAYDQAAYAVRG 102 9*****.******44465..********************99887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51032	22.431	52	110	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	3.2E-29	52	111	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	6.08E-22	52	111	IPR016177	DNA-binding domain
SMART	SM00380	2.8E-33	52	116	IPR001471	AP2/ERF domain
Pfam	PF00847	2.7E-13	53	102	IPR001471	AP2/ERF domain
CDD	cd00018	7.75E-28	53	109	No hit	No description
PRINTS	PR00367	2.3E-11	53	64	IPR001471	AP2/ERF domain
PRINTS	PR00367	2.3E-11	76	92	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 193 aa Download sequence Send to blast
MNRFFYPEIA STNHHVLPFN ENDSEEMLLF GVIADAHYVK QDDCLEQEKE LTYRGVRKRP 60 WGKFAAEIRD STRNGVRVWL GTFDTAEEAA LAYDQAAYAV RGSGTVLNFS EEFVFESLVK 120 MDYKYEEGSS PVLALKRKHT IKRKSMAKKM KKKEDKVVKV ENVVYLEDLG RDYLEELLGL 180 SESCSSNSSS SSW

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	8e-28	53	119	15	81	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Aan.6290	0.0	trichome

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Ubiquitously expressed, mostly in flowers and rosettes after ethylene treatment. {ECO:0000269\|PubMed:11950980}.

Functional Description ? help Back to Top
Source	Description
UniProt	Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression during the plant development, and/or mediated by stress factors and by components of stress signal transduction pathways. Seems to be a key integrator of ethylene and jasmonate signals in the regulation of ethylene/jasmonate-dependent defenses. Can mediate resistance to necrotizing fungi (Botrytis cinerea and Plectosphaerella cucumerina) and to soil borne fungi (Fusarium oxysporum conglutinans and Fusiarium oxysporum lycopersici), but probably not to necrotizing bacteria (Pseudomonas syringae tomato). {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains), independently of PAD4. Ethylene induction is completely dependent on functional ETHYLENE-INSENSITIVE2 (EIN2), ETHYLENE-INSENSITIVE3 (EIN3), which is itself a transcription factor and CORONATIVE-INSENSITIVE1 (COI1) proteins. Induction by jasmonate, B.cinerea or F.oxysporum as well as the synergistic induction by ethylene and jasmonate requires EIN2 and COI1. Induction by methyl jasmonate (MeJA) is independent of JAR1. Induction by salicylic acid (SA) is dependent on NPR1 but not on PAD4. Seems not to be induced by Alternaria brassicicola. {ECO:0000269\|PubMed:11950980, ECO:0000269\|PubMed:12060224, ECO:0000269\|PubMed:12509529, ECO:0000269\|PubMed:12805630, ECO:0000269\|PubMed:15242170, ECO:0000269\|PubMed:9851977}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023767742.1	2e-87	ethylene-responsive transcription factor 1B-like
Swissprot	Q8LDC8	2e-67	ERF92_ARATH; Ethylene-responsive transcription factor 1B
TrEMBL	J9PVZ8	1e-139	J9PVZ8_ARTAN; AP2-ERF transcription factor
STRING	EMJ07486	5e-69	(Prunus persica)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G23240.1	5e-44	ethylene response factor 1

Publications ? help Back to Top
Zarate SI,Kempema LA,Walling LL Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses. Plant Physiol., 2007. 143(2): p. 866-75 [PMID:17189328] Lu X, et al. Characterization of a novel ERF transcription factor in Artemisia annua and its induction kinetics after hormones and stress treatments. Mol. Biol. Rep., 2012. 39(10): p. 9521-7 [PMID:22714923] Vahabi K,Camehl I,Sherameti I,Oelmüller R Growth of Arabidopsis seedlings on high fungal doses of Piriformospora indica has little effect on plant performance, stress, and defense gene expression in spite of elevated jasmonic acid and jasmonic acid-isoleucine levels in the roots. Plant Signal Behav, 2013. 8(11): p. e26301 [PMID:24047645] Kim HG, et al. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Plant Physiol., 2013. 163(4): p. 1776-91 [PMID:24170202] Li J,Jia H,Wang J cGMP and ethylene are involved in maintaining ion homeostasis under salt stress in Arabidopsis roots. Plant Cell Rep., 2014. 33(3): p. 447-59 [PMID:24306353] Zhong S, et al. Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20 [PMID:24599595] Kim HG, et al. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. FEBS Lett., 2014. 588(9): p. 1652-8 [PMID:24631536] Schellingen K, et al. Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression. BMC Plant Biol., 2014. 14: p. 214 [PMID:25082369] Ellouzi H, et al. A comparative study of the early osmotic, ionic, redox and hormonal signaling response in leaves and roots of two halophytes and a glycophyte to salinity. Planta, 2014. 240(6): p. 1299-317 [PMID:25156490] Nguyen AH, et al. Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress. Plant Cell Physiol., 2015. 56(9): p. 1762-72 [PMID:26136597] Cheng MC,Kuo WC,Wang YM,Chen HY,Lin TP UBC18 mediates ERF1 degradation under light-dark cycles. New Phytol., 2017. 213(3): p. 1156-1167 [PMID:27787902] Timmermann T, et al. Paraburkholderia phytofirmans PsJN Protects Arabidopsis thaliana Against a Virulent Strain of Pseudomonas syringae Through the Activation of Induced Resistance. Mol. Plant Microbe Interact., 2017. 30(3): p. 215-230 [PMID:28118091] Yu Y,Huang R Integration of Ethylene and Light Signaling Affects Hypocotyl Growth in Arabidopsis. Front Plant Sci, 2017. 8: p. 57 [PMID:28174592] Lestari R, et al. Overexpression of Hevea brasiliensis ethylene response factor HbERF-IXc5 enhances growth and tolerance to abiotic stress and affects laticifer differentiation. Plant Biotechnol. J., 2018. 16(1): p. 322-336 [PMID:28626940] Dinolfo MI,Castañares E,Stenglein SA Resistance of Fusarium poae in Arabidopsis leaves requires mainly functional JA and ET signaling pathways. Fungal Biol, 2017. 121(10): p. 841-848 [PMID:28889908]