PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan000973

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

Dof

Protein Properties

Length: 286aa MW: 31924.3 Da PI: 9.0873

Description

Dof family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S41944432	PU_unref	Unigene	View CDS
PUT-183a-Artemisia_annua-118074	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-Dof	123.3	7.9e-39	64	123	2	61
zf-Dof 2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkks 61 ++k+++cprC s++tkfCy+nny+++qPr+fCk+C+ryWt+GGa+rn+PvG+grrknk+ Aan000973 64 PDKIIPCPRCTSMDTKFCYFNNYNVNQPRHFCKSCQRYWTAGGAMRNMPVGAGRRKNKNL 123 7899*****************************************************986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
ProDom	PD007478	7.0E-31	56	121	IPR003851	Zinc finger, Dof-type
Pfam	PF02701	2.5E-31	66	122	IPR003851	Zinc finger, Dof-type
PROSITE profile	PS50884	28.258	68	122	IPR003851	Zinc finger, Dof-type
PROSITE pattern	PS01361	0	70	106	IPR003851	Zinc finger, Dof-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 286 aa Download sequence Send to blast
MEDPGIKLFG KKIVLPDKDL LKVNESEARP ESGSPKTPSI NEKTRTEESE QEATNQQPKT 60 LKKPDKIIPC PRCTSMDTKF CYFNNYNVNQ PRHFCKSCQR YWTAGGAMRN MPVGAGRRKN 120 KNLASQCRYI TISQESVTTS VTVPENIQNN ISIPGVSLPY NPWNPAVPIP SVCPPLPVYP 180 SVYWNCIPFL PPSTPSSDPI LGKRVRDDDL EKPNNSILIP KTLRIDDPDE AAKSSIWATL 240 GIKNENFKAF QGKSKDSKKH QETTNSPTLQ ANPAAFSRSL CFQETA

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in the vascular tissues of cotyledons, leaves and hypocotyls and in stomata. Not detected in roots. {ECO:0000269\|PubMed:16002617}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence. A flanking TGT sequence contributes to the specificity of binding. Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The DNA-binding ability is not modulated by 'GIGANTEA' but the stability of CDF1 is controlled by the proteasome-dependent pathway. Ubiquitinated by the SCF(ADO3) E3 ubiquitin ligase complex. Binds to the FT promoter in the morning. {ECO:0000269\|PubMed:16002617, ECO:0000269\|PubMed:19619493, ECO:0000269\|PubMed:22628657}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Circadian-regulation at the protein level, but not at the mRNA level. Strongly decreased expression during the dark phase. Accumulates at high levels at the beginning of the day. {ECO:0000269\|PubMed:16002617}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024976751.1	1e-135	cyclic dof factor 1-like
Swissprot	Q8W1E3	6e-74	CDF1_ARATH; Cyclic dof factor 1
TrEMBL	A0A2U1L144	0.0	A0A2U1L144_ARTAN; DOF transcription factor 2
STRING	Migut.D01811.1.p	8e-77	(Erythranthe guttata)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G62430.1	3e-76	cycling DOF factor 1

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Seaton DD, et al. Linked circadian outputs control elongation growth and flowering in response to photoperiod and temperature. Mol. Syst. Biol., 2015. 11(1): p. 776 [PMID:25600997] Goralogia GS, et al. CYCLING DOF FACTOR 1 represses transcription through the TOPLESS co-repressor to control photoperiodic flowering in Arabidopsis. Plant J., 2017. 92(2): p. 244-262 [PMID:28752516] Henriques R, et al. The antiphasic regulatory module comprising CDF5 and its antisense RNA FLORE links the circadian clock to photoperiodic flowering. New Phytol., 2017. 216(3): p. 854-867 [PMID:28758689]