PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK43521.1
Organism
Arabis alpina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family bHLH
Protein Properties Length: 601aa    MW: 66769.6 Da    PI: 6.9272
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK43521.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH37.93.1e-1267119155
                 CHHHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
         HLH   1 rrrahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                 +r++h e+E+ RR+++ s f +Lr +lP+      ++K s ++ + +Av+YI  Lq
  KFK43521.1  67 KRAKHREIEKHRRQEVTSLFGKLRYMLPShY---IKGKRSSSDHVLEAVNYIIGLQ 119
                 79***************************77...******************9998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474592.09E-1363141IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.32E-864123No hitNo description
PROSITE profilePS5088812.14466118IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.9E-967119IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.1E-967136IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd121561.30E-154280584No hitNo description
SuperFamilySSF522831.76E-25290416No hitNo description
Gene3DG3DSA:3.40.50.7201.0E-26294393IPR016040NAD(P)-binding domain
PfamPF003893.0E-20322592IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
SuperFamilySSF517354.94E-49380561IPR016040NAD(P)-binding domain
PfamPF028264.6E-48389561IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
Gene3DG3DSA:3.40.50.7205.7E-50394564IPR016040NAD(P)-binding domain
PROSITE patternPS000650427454IPR029752D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0055114Biological Processoxidation-reduction process
GO:0016616Molecular Functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046983Molecular Functionprotein dimerization activity
GO:0051287Molecular FunctionNAD binding
Sequence ? help Back to Top
Protein Sequence    Length: 601 aa     Download sequence    Send to blast
MDFTSSSLFT PDFAYENGLD FSNLFTPSTF IPFEEPNPCN AISHVENNDG KHIISEITKG  60
VEERENKRAK HREIEKHRRQ EVTSLFGKLR YMLPSHYIKG KRSSSDHVLE AVNYIIGLQK  120
KIKEMREKRD RIKRDITHPT STRECFIRLL SPSPSLSSNC SCVGDKHIDV KVRTCLVGIE  180
IVASCCFRNE YCLSRVLQLL DQEQCLNVVS CISTRLDQRF MHTIVSEVEE EKEVDFSELQ  240
EKIIRACLSM SLKDERDREW WASATTQQSK SMSASSVPPP LILVHRPPSL TFTADILSRN  300
FRILTIPSSS DDPLPIFLSR HASSIRAFVN IARLPVTGEL LSYLPSLQII VNTSVGVDHI  360
DLAECKRRGI VVTNGGDAYS EDVADTAVSL LISVLRRIPA ADRFVRSGSW VESGDFPLGI  420
KVSGKRVGIV GLGSIGSLIA KRLKPFSCII SYHSRSHKAD TPYRFYPDIL SLAAENDVLV  480
LCCSLTDQTR HVVNREVMES LGKAGVIINV GRGGLIDEKE MVKCLVQGVI GGAGLDVFEN  540
EPEVPEELLG LDNVVLSPHA AVLTAGSLNN AAELALANLK AFFSNRPLVS PVQLDLIDRQ  600
V
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ba1_A3e-9030159247332Hydroxyphenylpyruvate reductase
3baz_A3e-9030159247332Hydroxyphenylpyruvate reductase
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1118133QKKIKEMREKRDRIKR
Functional Description ? help Back to Top
Source Description
UniProtCatalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate (HP) into glycolate and glycerate. Mostly active in the presence of NADPH and glyoxylate. {ECO:0000269|PubMed:21205613}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK43521.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006417223.11e-178glyoxylate/hydroxypyruvate reductase HPR3
SwissprotQ9LE331e-171HPR3_ARATH; Glyoxylate/hydroxypyruvate reductase HPR3
TrEMBLA0A087HN190.0A0A087HN19_ARAAL; Uncharacterized protein
STRINGA0A087HN190.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM86122
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12540.15e-99bHLH family protein
Publications ? help Back to Top
  1. Timm S, et al.
    A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis.
    Plant Cell, 2008. 20(10): p. 2848-59
    [PMID:18952776]
  2. Timm S, et al.
    The hydroxypyruvate-reducing system in Arabidopsis: multiple enzymes for the same end.
    Plant Physiol., 2011. 155(2): p. 694-705
    [PMID:21205613]