PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | KFK36495.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 479aa MW: 52555.4 Da PI: 4.77 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 85.4 | 4.3e-27 | 163 | 228 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++++g ++lne+ak+L dv ++RRiYDi+NVLe+++liek kn+i wkg KFK36495.1 163 RYDNSLGLLTKKFVNLIKQAKDGLLDLNEAAKTL---DV--QKRRIYDITNVLEGIDLIEKPLKNQILWKG 228 689*******************************...**..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 3.0E-27 | 161 | 230 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.4E-32 | 163 | 228 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.77E-16 | 163 | 226 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 3.6E-23 | 165 | 228 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF144074 | 3.66E-32 | 241 | 345 | No hit | No description |
CDD | cd14660 | 1.08E-47 | 241 | 345 | No hit | No description |
Pfam | PF16421 | 3.0E-33 | 244 | 343 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0045893 | Biological Process | positive regulation of transcription, DNA-templated | ||||
GO:0051446 | Biological Process | positive regulation of meiotic cell cycle | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 479 aa Download sequence Send to blast |
MSGVVRSSPN PTHSRPPPPR HPPSSPSPAT STTVVPPLRR HLAFASTKPP FHPSDDYHRF 60 NPNDNNNSSS LVNGCGVVDR EDDAVVVRSP SRKRKSTMDV APSHNGFTSS GFTSIPSSPY 120 KSPVSAKGGR VNIKSKAKGT KSTPQKPISN ADSPATLTPG SCRYDNSLGL LTKKFVNLIK 180 QAKDGLLDLN EAAKTLDVQK RRIYDITNVL EGIDLIEKPL KNQILWKGVE SSRPGDMDAD 240 VSVLQAEIES LALEEQALDH QIRETEERLR DLSENEKNQK WLFVTEEDIK SLPGFQNQTL 300 IAVKAPHGTT LEVPDPDEAA DHPQRRYRII LRSTMGPIDV YLVSEFEGKF EDTNGSAPPP 360 CLPIASCSGS TENHDIEALT IDNTETAIEN QVLHDHVQPG DNSDLNYLQE QVGGMLKITP 420 TDAENDDTDY WLLSNAEISM TDIWKSDSGI DWDYGIADVS TPPPEMDEIL PNAVDSTAR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
1cf7_A | 8e-23 | 159 | 229 | 2 | 74 | PROTEIN (TRANSCRIPTION FACTOR E2F-4) |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 90 | 95 | SRKRKS |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00293 | DAP | Transfer from AT2G36010 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | KFK36495.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AF242582 | 0.0 | AF242582.1 Arabidopsis thaliana E2F transcription factor-3 E2F3 mRNA, complete cds. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006410774.1 | 0.0 | transcription factor E2FA | ||||
Swissprot | Q9FNY0 | 0.0 | E2FA_ARATH; Transcription factor E2FA | ||||
TrEMBL | A0A087H2Z3 | 0.0 | A0A087H2Z3_ARAAL; Uncharacterized protein | ||||
STRING | A0A087H2Z3 | 0.0 | (Arabis alpina) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT2G36010.1 | 0.0 | E2F transcription factor 3 |
Publications ? help Back to Top | |||
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