PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | KFK34109.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
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Family | E2F/DP | ||||||||
Protein Properties | Length: 390aa MW: 44044.1 Da PI: 7.3925 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 74.7 | 9.8e-24 | 19 | 84 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl+l++++ ++v l+++a++L v +rRRiYDi+NVLe+++++++++kn+++wkg KFK34109.1 19 RKQKSLGLLCTNFLALYNREGIETVGLDDAATKL---GV--ERRRIYDIVNVLESVGVLTRRAKNQYTWKG 84 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 79.8 | 2.4e-25 | 158 | 238 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +se++i++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k++++w g KFK34109.1 158 RREKSLGLLTQNFIKLFVCSEARIISLDEAAKLLLGDahntsIMRTKVRRLYDIANVLSSMNLIEKthtldSRKPAFKWLG 238 689**************************************999************************9999*******87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 1.2E-26 | 15 | 86 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 1.66E-16 | 18 | 82 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 5.0E-29 | 19 | 84 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 7.6E-21 | 20 | 84 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.4E-23 | 156 | 239 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.2E-32 | 158 | 238 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.74E-14 | 160 | 239 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 3.3E-20 | 160 | 238 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 390 aa Download sequence Send to blast |
MALSSPPESS SSLHHSYSRK QKSLGLLCTN FLALYNREGI ETVGLDDAAT KLGVERRRIY 60 DIVNVLESVG VLTRRAKNQY TWKGFDAIPA ALKELQEEGA KDTFHRFYTN ENVKVSDDED 120 DDEESSQPSS QTDSSKAGSL PQTSDSSKIG WSCVTDNRRE KSLGLLTQNF IKLFVCSEAR 180 IISLDEAAKL LLGDAHNTSI MRTKVRRLYD IANVLSSMNL IEKTHTLDSR KPAFKWLGYN 240 GEPTFTFTLS NDLMQAESRK RVFGTDITNV NVKRSKTHEN AASERTLKMK KHAVEESSCN 300 KSFDTTHESR HGSRGYQFGP FAPATGTYPT ATLDDNSRRA FDVENLVSDY RPSYQNQVLK 360 DLFAHYMDAW KEWYSEVTKK DPLPNTSPHH |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 2e-39 | 18 | 230 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | KFK34109.1 |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | Retrieve |
Annotation -- Nucleotide ? help Back to Top | ||||||
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Source | Hit ID | E-value | Description | |||
GenBank | AK353197 | 0.0 | AK353197.1 Thellungiella halophila mRNA, complete cds, clone: RTFL01-26-N13. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_006404291.1 | 0.0 | E2F transcription factor-like E2FE | ||||
Swissprot | Q8LSZ4 | 0.0 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A087GW57 | 0.0 | A0A087GW57_ARAAL; Uncharacterized protein | ||||
STRING | A0A087GW57 | 0.0 | (Arabis alpina) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6304 | 27 | 43 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 0.0 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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