PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK32783.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

GRF

Protein Properties

Length: 515aa MW: 55481.6 Da PI: 9.3829

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK32783.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	78.3	7.3e-25	189	233	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e KFK32783.1 189 DPEPGRCRRTDGKKWRCSRDAVPDQKYCERHINRGRHRSRKPVEG 233 79****************************************985 PP
2	QLQ	49.9	1e-17	125	161	1	37
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 ++F+ +Q+++L++Q+l+yKy+ an PvP+ Ll+ ++k KFK32783.1 125 GPFSLTQWAELEQQALIYKYITANIPVPSSLLLSLKK 161 59******************************99875 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	3.0E-10	125	161	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	20.325	126	161	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	6.2E-12	126	158	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.954	189	233	IPR014977	WRC domain
Pfam	PF08879	3.3E-21	190	232	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009624	Biological Process	response to nematode
GO:0048364	Biological Process	root development
GO:0048366	Biological Process	leaf development
GO:0061062	Biological Process	regulation of nematode larval development
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 515 aa Download sequence Send to blast
MDLGVRVQGS VSGHENGSPG QPELGSSLSS KQERYGFDGE DCWRSSKVAR TTPETMSFHQ 60 GIPLLRSTSI LSSDPRNRQE HMLSFSSDKS DVSPYLQYCK NSGYGLGGMM NTSSMHGNLL 120 TGVKGPFSLT QWAELEQQAL IYKYITANIP VPSSLLLSLK KSFFPYGSLP PNSFGWGSFH 180 LGFSGGNMDP EPGRCRRTDG KKWRCSRDAV PDQKYCERHI NRGRHRSRKP VEGQNGHNTT 240 NAAAAASTAA SKAVATTVVA MRGSDNNNSL ASVGNHHLHA NPSTDSLANR VQISRGGSVY 300 PASMNLQLKE SHPKQSNNPF EFGLISSDSL LNPSHKQASY ANSSKGFGSY LDFSNQAKHS 360 GNHHNVDSWP EELKSDWTQL SMSIPMAPSS PVQDKLALSP LRLSREFDPA IHMGLGVNTE 420 FLEPAKKVNN WIPISWGNHN SMGGPLGEVL NSTTNSPKFG SSPTGVLQKS TFGSLSNSSS 480 GSSTVVGENN HKNGDGKDPL GPTTLMNSSA TAPSL

Sequence ? help Back to Top

Protein Sequence Length: 515 aa Download sequence Send to blast

MDLGVRVQGS VSGHENGSPG QPELGSSLSS KQERYGFDGE DCWRSSKVAR TTPETMSFHQ  60
GIPLLRSTSI LSSDPRNRQE HMLSFSSDKS DVSPYLQYCK NSGYGLGGMM NTSSMHGNLL  120
TGVKGPFSLT QWAELEQQAL IYKYITANIP VPSSLLLSLK KSFFPYGSLP PNSFGWGSFH  180
LGFSGGNMDP EPGRCRRTDG KKWRCSRDAV PDQKYCERHI NRGRHRSRKP VEGQNGHNTT  240
NAAAAASTAA SKAVATTVVA MRGSDNNNSL ASVGNHHLHA NPSTDSLANR VQISRGGSVY  300
PASMNLQLKE SHPKQSNNPF EFGLISSDSL LNPSHKQASY ANSSKGFGSY LDFSNQAKHS  360
GNHHNVDSWP EELKSDWTQL SMSIPMAPSS PVQDKLALSP LRLSREFDPA IHMGLGVNTE  420
FLEPAKKVNN WIPISWGNHN SMGGPLGEVL NSTTNSPKFG SSPTGVLQKS TFGSLSNSSS  480
GSSTVVGENN HKNGDGKDPL GPTTLMNSSA TAPSL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:22419826, ECO:0000269\|PubMed:22751317}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK32783.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:22419826}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006404750.1	0.0	growth-regulating factor 1
Swissprot	O81001	0.0	GRF1_ARATH; Growth-regulating factor 1
TrEMBL	A0A087GSD1	0.0	A0A087GSD1_ARAAL; Uncharacterized protein
STRING	A0A087GSD1	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1454	28	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22840.1	0.0	growth-regulating factor 1

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]