PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK29053.1
Organism
Arabis alpina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family HD-ZIP
Protein Properties Length: 670aa    MW: 76075.8 Da    PI: 5.3369
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK29053.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox50.43.7e-163183556
                SS--HHHHHHHHHHHHH.SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
    Homeobox  5 ttftkeqleeLeelFek.nrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                +++t++q++ Le +F++ ++ p++++r eL + ++L+ +qVk+WFqNrR++e+
  KFK29053.1 31 HRHTTQQIQLLEIFFKEcTPFPDENQRSELGQMVNLDAQQVKFWFQNRRTQER 83
                689*************99********************************998 PP
2START128.95.9e-412004182205
                 HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS....SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S.......EEEEEEEEC CS
       START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv...dsgealrasgvvdmvlallveellddkeqWdetla.......kaetlevis 86 
                 +a++a++elv + +  +p+W + s    e +++ e+ + f  s     + +e +r++g+v m++ +lv +l+d + +W   +        + +++ +  
  KFK29053.1 200 IANAAMNELVMLGKIYCPFWRLNSgstrETLDYIEYESVFNNSIKppgFVIESSRDTGLVLMTSLDLVTTLMDMN-KWVDVFGpivsdatSRKLIST-- 295
                 6899********************7766555555555555444449999**************************.******999995544444444.. PP

                 TT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.-TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXXH CS
       START  87 sg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppesssvvRaellpSgiliepksnghskvtwvehvdlkgrlph 178
                         g lq + ae+ ++s lvp R ++f+Ry++ l++g+w++vd  v+++q +p+  s+  +++lpSg++ie+ +n ++ vtw+e + +++ ++h
  KFK29053.1 296 -SpggtrnGSLQMIEAEFLVPSLLVPkRQVTFLRYCKLLREGVWAVVD--VTPTQLNPNLLSYGGSTRLPSGLIIEEIANDYCMVTWIELTAYDETHIH 391
                 .4446*******************************************..99999999999************************************** PP

                 HHHHHHHHHHHHHHHHHHHHHTXXXXX CS
       START 179 wllrslvksglaegaktwvatlqrqce 205
                 +++r+l++ g+  ga++w++tlqr+c+
  KFK29053.1 392 QMYRPLIGGGIGLGARRWLKTLQRHCQ 418
                 **************************8 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466891.92E-141683IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.7E-161783IPR009057Homeodomain-like
PROSITE profilePS5007115.1922485IPR001356Homeobox domain
SMARTSM003898.9E-112589IPR001356Homeobox domain
CDDcd000861.04E-112883No hitNo description
PfamPF000461.2E-133083IPR001356Homeobox domain
PROSITE profilePS5084829.431190422IPR002913START domain
CDDcd088754.23E-74195418No hitNo description
SMARTSM002343.3E-37199419IPR002913START domain
SuperFamilySSF559614.12E-14200418No hitNo description
PfamPF018522.4E-36200418IPR002913START domain
SuperFamilySSF559618.93E-14440633No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006349Biological Processregulation of gene expression by genetic imprinting
GO:0009911Biological Processpositive regulation of flower development
GO:0031047Biological Processgene silencing by RNA
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0008289Molecular Functionlipid binding
GO:0042803Molecular Functionprotein homodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 670 aa     Download sequence    Send to blast
MSDGESDYEI FNSSFISEDD EQVGPRIQRY HRHTTQQIQL LEIFFKECTP FPDENQRSEL  60
GQMVNLDAQQ VKFWFQNRRT QERMNLRRRE NVTLRREHVR LLGEHEKLRQ ERLLSLCNIC  120
RMPTNYCEVS NEEQQLTIEN ARLKQEIGQI FSLICKDFQL PAGLSAAQPS SSLMSSNAPR  180
ELDSGGRNSM MNQNSMLLDI ANAAMNELVM LGKIYCPFWR LNSGSTRETL DYIEYESVFN  240
NSIKPPGFVI ESSRDTGLVL MTSLDLVTTL MDMNKWVDVF GPIVSDATSR KLISTSPGGT  300
RNGSLQMIEA EFLVPSLLVP KRQVTFLRYC KLLREGVWAV VDVTPTQLNP NLLSYGGSTR  360
LPSGLIIEEI ANDYCMVTWI ELTAYDETHI HQMYRPLIGG GIGLGARRWL KTLQRHCQIL  420
SSMWTVNLTQ DFSEMPAKVR AEIVKLAQRM TLNYYLGISN SSASKWKSIQ VENEEQNMRL  480
MIRKNMNEPG ELTGIVLSAA TSVWFPVNHQ QMFDFLTNQN FRGQWDILTH NSSMEEKIRI  540
HIANRHGNYV SLLKIVENDM LVLQEIWNDA SGAMVVYAPV ETHSMEKVIN GADSDFMQFL  600
SSGFSILPDK EAELDKGEDN GSGGCLLTLG LQVWVSSKPT TELTQSLVRT VEGLLDCTIG  660
NIISGLLRAT
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor involved in the regulation of time of flowering through the photoperiod flowering pathway. May repress FT. {ECO:0000269|PubMed:17189287}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK29053.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_567722.10.0FLOWERING WAGENINGEN
SwissprotQ9FVI60.0FWA_ARATH; Homeobox-leucine zipper protein HDG6
TrEMBLA0A087GGQ10.0A0A087GGQ1_ARAAL; Homeodomain-containing transcription factor fwa
STRINGA0A087GGQ10.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM49128149
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G25530.10.0FLOWERING WAGENINGEN
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Rea M, et al.
    Determination of DNA methylation of imprinted genes in Arabidopsis endosperm.
    J Vis Exp, 2011.
    [PMID:21307831]
  3. Nakamura M, et al.
    The role of Arabidopsis thaliana NAR1, a cytosolic iron-sulfur cluster assembly component, in gametophytic gene expression and oxidative stress responses in vegetative tissue.
    New Phytol., 2013. 199(4): p. 925-35
    [PMID:23734982]
  4. Xu Y,Gan ES,He Y,Ito T
    Flowering and genome integrity control by a nuclear matrix protein in Arabidopsis.
    Nucleus, 2013 Jul-Aug. 4(4): p. 274-6
    [PMID:23836195]
  5. Jones AL,Sung S
    Mechanisms underlying epigenetic regulation in Arabidopsis thaliana.
    Integr. Comp. Biol., 2014. 54(1): p. 61-7
    [PMID:24808013]
  6. Buzas DM,Nakamura M,Kinoshita T
    Epigenetic role for the conserved Fe-S cluster biogenesis protein AtDRE2 in Arabidopsis thaliana.
    Proc. Natl. Acad. Sci. U.S.A., 2014. 111(37): p. 13565-70
    [PMID:25197096]
  7. Bond DM,Baulcombe DC
    Epigenetic transitions leading to heritable, RNA-mediated de novo silencing in Arabidopsis thaliana.
    Proc. Natl. Acad. Sci. U.S.A., 2015. 112(3): p. 917-22
    [PMID:25561534]
  8. Li Y, et al.
    An AP endonuclease functions in active DNA demethylation and gene imprinting in Arabidopsis [corrected].
    PLoS Genet., 2015. 11(1): p. e1004905
    [PMID:25569774]
  9. Sornay E,Forzani C,Forero-Vargas M,Dewitte W,Murray JA
    Activation of CYCD7;1 in the central cell and early endosperm overcomes cell-cycle arrest in the Arabidopsis female gametophyte, and promotes early endosperm and embryo development.
    Plant J., 2015. 84(1): p. 41-55
    [PMID:26261067]
  10. Wang L, et al.
    Tetrahydrofolate Modulates Floral Transition through Epigenetic Silencing.
    Plant Physiol., 2017. 174(2): p. 1274-1284
    [PMID:28450424]
  11. Gallego-Bartolomé J, et al.
    Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain.
    Proc. Natl. Acad. Sci. U.S.A., 2018. 115(9): p. E2125-E2134
    [PMID:29444862]