PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KFK25413.1

Organism

Arabis alpina

Taxonomic ID

50452

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis

Family

MYB

Protein Properties

Length: 948aa MW: 106243 Da PI: 5.3184

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KFK25413.1	genome	MPIPBR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	58.4	1.6e-18	36	82	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg WT+eEde+l +av+ + g++Wk+Ia+++ Rt+ qc +rwqk+l KFK25413.1 36 RGQWTAEEDEILRKAVHSFKGKNWKKIAEYFK-DRTDVQCLHRWQKVL 82 89***************************9.**********986 PP
2	Myb_DNA-binding	62.1	1.2e-19	88	134	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEde ++++++++G++ W+tIar ++ gR +kqc++rw+++l KFK25413.1 88 KGPWTKEEDEMIIQLIEKYGPKKWSTIARFLP-GRIGKQCRERWHNHL 134 79****************************.***********97 PP
3	Myb_DNA-binding	43	1e-13	140	182	1	45
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + +WT+eE++ l++a++ +G++ W+ + ++ gR+++ +k++w+ KFK25413.1 140 KEAWTQEEELVLIRAHQIYGNR-WAELTKFLP-GRSDNGIKNHWH 182 579*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	19.294	31	82	IPR017930	Myb domain
SMART	SM00717	1.2E-15	35	84	IPR001005	SANT/Myb domain
Pfam	PF00249	2.1E-16	36	82	IPR001005	SANT/Myb domain
SuperFamily	SSF46689	2.15E-15	37	92	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	8.3E-23	37	90	IPR009057	Homeodomain-like
CDD	cd00167	4.17E-14	39	82	No hit	No description
PROSITE profile	PS51294	32.774	83	138	IPR017930	Myb domain
SuperFamily	SSF46689	1.12E-31	85	181	IPR009057	Homeodomain-like
SMART	SM00717	2.1E-19	87	136	IPR001005	SANT/Myb domain
Pfam	PF00249	8.3E-18	88	134	IPR001005	SANT/Myb domain
CDD	cd00167	2.99E-17	90	134	No hit	No description
Gene3D	G3DSA:1.10.10.60	8.8E-28	91	138	IPR009057	Homeodomain-like
SMART	SM00717	1.5E-12	139	187	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	1.6E-19	139	189	IPR009057	Homeodomain-like
PROSITE profile	PS51294	18.094	139	189	IPR017930	Myb domain
Pfam	PF00249	9.4E-12	140	182	IPR001005	SANT/Myb domain
CDD	cd00167	9.35E-10	142	182	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0032875	Biological Process	regulation of DNA endoreduplication
GO:0003677	Molecular Function	DNA binding
GO:0003713	Molecular Function	transcription coactivator activity

Sequence ? help Back to Top
Protein Sequence Length: 948 aa Download sequence Send to blast
MESECTPIST PPEGLIEGNT KTRHGRTSGP ARRSTRGQWT AEEDEILRKA VHSFKGKNWK 60 KIAEYFKDRT DVQCLHRWQK VLNPELVKGP WTKEEDEMII QLIEKYGPKK WSTIARFLPG 120 RIGKQCRERW HNHLNPAINK EAWTQEEELV LIRAHQIYGN RWAELTKFLP GRSDNGIKNH 180 WHSSVKKKLD SYMASGLLDQ YQAMPLAPYE RSSTLQSTFM QRTIDENDCL SGQVENEMEN 240 HQNASMVGCS LSARDYPNGV VNMGQHFYPC ENSHENAQAA YHPDQYFFPE LEDISVSISE 300 VSYDMEDCSQ FRDHNVSASS SQDYHFDFQE LSDISLEMRH NMSDVQMPYT NESKESTMGA 360 LNSTGNIDVA TCTNPANVLT SETECCRILF PDQESGGLSV STSLTQELNE VDQADSRVPT 420 FGASASDSQI SEATKSPMQS SSSRFIAKAA SGKATLRPAP LIISPDKYAK KSSGLICHPF 480 EATPKCTTNP NGSFICIDDP SSSCVDEGTN NSSEEDQSYH VNDSKKLVAV NDFASLAEVK 540 PQSLPKHEPN MTSEEHHEDI GASSSHCFPS LDVPVFSSDL LQSKNDLLHD YSPLGIRKLL 600 MSTMTCMSPL RLWESPTGKK TLVGAKSILR KRTRDLLTPL SEKRCEKKLE TDIAASLAKD 660 FSRLDVMFDE SENRESISGN SNSGILGERE NHYQILIGEG KETMHIRKSL EKAVQTCMEA 720 NVREKDASEP YVENAENFSG VLSENNTNKS ALSPPGQSIT KAEKAQLSTP RNHLQRTFMA 780 TSNKEQLCLV INSPSRVRNT EGHLVDSETS NENFSIFCGT PFRRSLESPS AWKSPFYVNS 840 LLPSPRFDTE ITIEDMGYIF SPGERSYEGI GVMTQRNEHT NAFAAFTDAM EVSLSPSTDY 900 AMQKKELDKE NNDPLVAERR VLDFNDCESP IKATEQVSSS YNLLKGCR

Sequence ? help Back to Top

Protein Sequence Length: 948 aa Download sequence Send to blast

MESECTPIST PPEGLIEGNT KTRHGRTSGP ARRSTRGQWT AEEDEILRKA VHSFKGKNWK  60
KIAEYFKDRT DVQCLHRWQK VLNPELVKGP WTKEEDEMII QLIEKYGPKK WSTIARFLPG  120
RIGKQCRERW HNHLNPAINK EAWTQEEELV LIRAHQIYGN RWAELTKFLP GRSDNGIKNH  180
WHSSVKKKLD SYMASGLLDQ YQAMPLAPYE RSSTLQSTFM QRTIDENDCL SGQVENEMEN  240
HQNASMVGCS LSARDYPNGV VNMGQHFYPC ENSHENAQAA YHPDQYFFPE LEDISVSISE  300
VSYDMEDCSQ FRDHNVSASS SQDYHFDFQE LSDISLEMRH NMSDVQMPYT NESKESTMGA  360
LNSTGNIDVA TCTNPANVLT SETECCRILF PDQESGGLSV STSLTQELNE VDQADSRVPT  420
FGASASDSQI SEATKSPMQS SSSRFIAKAA SGKATLRPAP LIISPDKYAK KSSGLICHPF  480
EATPKCTTNP NGSFICIDDP SSSCVDEGTN NSSEEDQSYH VNDSKKLVAV NDFASLAEVK  540
PQSLPKHEPN MTSEEHHEDI GASSSHCFPS LDVPVFSSDL LQSKNDLLHD YSPLGIRKLL  600
MSTMTCMSPL RLWESPTGKK TLVGAKSILR KRTRDLLTPL SEKRCEKKLE TDIAASLAKD  660
FSRLDVMFDE SENRESISGN SNSGILGERE NHYQILIGEG KETMHIRKSL EKAVQTCMEA  720
NVREKDASEP YVENAENFSG VLSENNTNKS ALSPPGQSIT KAEKAQLSTP RNHLQRTFMA  780
TSNKEQLCLV INSPSRVRNT EGHLVDSETS NENFSIFCGT PFRRSLESPS AWKSPFYVNS  840
LLPSPRFDTE ITIEDMGYIF SPGERSYEGI GVMTQRNEHT NAFAAFTDAM EVSLSPSTDY  900
AMQKKELDKE NNDPLVAERR VLDFNDCESP IKATEQVSSS YNLLKGCR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	8e-69	36	189	6	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	8e-69	36	189	6	159	MYB PROTO-ONCOGENE PROTEIN
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269\|PubMed:17287251, ECO:0000269\|PubMed:21862669, ECO:0000269\|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269\|PubMed:20018666}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00505	DAP	Transfer from AT5G11510	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KFK25413.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269\|PubMed:16463103, ECO:0000269\|PubMed:17287251}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF371975	0.0	AF371975.2 Arabidopsis thaliana putative c-myb-like transcription factor MYB3R-4 (MYB3R4) mRNA, complete cds.
GenBank	AY519650	0.0	AY519650.1 Arabidopsis thaliana MYB transcription factor (At5g11510) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006399657.1	0.0	transcription factor MYB3R-4
Swissprot	Q94FL9	0.0	MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBL	A0A087G6B1	0.0	A0A087G6B1_ARAAL; Myb-related protein 3r-1-like
STRING	A0A087G6B1	0.0	(Arabis alpina)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM13213	18	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G11510.1	0.0	myb domain protein 3r-4

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Saito T, et al. Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana. Plant Signal Behav, 2015. 10(3): p. e990817 [PMID:25806785] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]