PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK24872.1
Organism
Arabis alpina
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family C2H2
Protein Properties Length: 1333aa    MW: 149102 Da    PI: 6.5491
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK24872.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.20.0005712451268223
                  EET..TTTEEESSHHHHHHHHHHT CS
     zf-C2H2    2 kCp..dCgksFsrksnLkrHirtH 23  
                  +C+   Cgk F+ + +L++H+r+H
  KFK24872.1 1245 RCTheGCGKKFRAHKYLVHHQRVH 1268
                  588889****************99 PP
2zf-C2H211.50.0009213041330123
                  EEET..TTTEEESSHHHHHHHHHH..T CS
     zf-C2H2    1 ykCp..dCgksFsrksnLkrHirt..H 23  
                  y+C+   Cg sF+  s++ rH r+  H
  KFK24872.1 1304 YVCKieECGLSFRFVSDYSRHRRKtgH 1330
                  99*********************9777 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM005453.2E-141555IPR003349JmjN domain
PROSITE profilePS5118313.6611657IPR003349JmjN domain
PfamPF023756.5E-151750IPR003349JmjN domain
SMARTSM005582.7E-46263432IPR003347JmjC domain
PROSITE profilePS5118435.496266432IPR003347JmjC domain
SuperFamilySSF511971.26E-26278430No hitNo description
PfamPF023732.2E-37296415IPR003347JmjC domain
SMARTSM003553112211243IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015713.15212441273IPR007087Zinc finger, C2H2
SMARTSM003550.1512441268IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.602.0E-612451267IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS00028012461268IPR007087Zinc finger, C2H2
SuperFamilySSF576671.31E-1012601302No hitNo description
Gene3DG3DSA:3.30.160.601.1E-1212681296IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.48412741303IPR007087Zinc finger, C2H2
SMARTSM003550.00712741298IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028012761298IPR007087Zinc finger, C2H2
SuperFamilySSF576671.34E-812921326No hitNo description
Gene3DG3DSA:3.30.160.608.0E-1012971327IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.61913041333IPR007087Zinc finger, C2H2
SMARTSM003555.513041330IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028013061330IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009741Biological Processresponse to brassinosteroid
GO:0009826Biological Processunidimensional cell growth
GO:0032259Biological Processmethylation
GO:0033169Biological Processhistone H3-K9 demethylation
GO:0048577Biological Processnegative regulation of short-day photoperiodism, flowering
GO:0048579Biological Processnegative regulation of long-day photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0008168Molecular Functionmethyltransferase activity
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 1333 aa     Download sequence    Send to blast
MGNVEIPNWL KALPSAPVYR PTDTEFADPI AYISKIEKEA SVFGICKIIP PLPKPSKKYV  60
FHNLNKSLLK CPELVSDADI SKVCGEDRAV FTTRQQELGQ VGKKGKKGES SKSSSLRSGV  120
KQVWESGGVY TLEQFETKSK TFYKSQLGTV KEVSPVVVEA LFWKAALEKP MYIEYANDVP  180
GSAFGEPEGH YRHFRQRKRR GRGFYQRKPE INDGQDTSGR NGESTSLEVE KASLASTSLL  240
AEDSSKQKNL EIVDEMEGTA GWKLSNSSWN LQMIARSPGS VTRFMPDDIP GVTSPMVYIG  300
MLFSWFAWHV EDHELHSMNY LHTGSPKTWY AVPADYALDF EEVIRKNSYG RDIDQLAALT  360
QLGEKTTLVS PEMIVASGIP CCRLVQNPGD FVVTFPRSYH VGFSHGFNCG EAANFGTPQW  420
LSVAKEAAVR RAAMNYLPML SHQQLLYLLT IVPRSLLPGG RSSRLRDRQR EEREFLVKKA  480
FVEDILNENK NLSVLHREPG FRLVMWDPYQ LPRHSALALA AAETAFSSPA VAKSELEDGH  540
SGMQNKEKTT LLEELSLFME KLNDVYYDDD DGLLNDFQVD TGTLACVACG VLGFPFMSVV  600
QPSEKALKDL SESQGEIDAQ KITTLSDCEW NTSSRCIRPR IFCLEHTIEL QRLLQSRGGL  660
KFLVICHKDF QKFKAHAAIV AEEVKVPFSY DDVLLESASQ EELSLIDLAI EDEENNEHGV  720
DWTSKLGINL RYCVKVRKNS PTTKIQHALS PGGLFSDTSH MLDFSTIRWL QRKSRSKTKP  780
IPISSFTPRE HLEVKVDGKL GESLDSQVRR KEEKIIQYSR KKKLNPKPSG EQGQELATLA  840
ISKDLDNTCN KLANRSNPDS AIHSEMNNEI RNSERAIGRN GVSFCENPCS SSFTGAHGEE  900
HPEITVKFGS ALDGNITNSS SKVNEDTANI TSEIREPQGH SMTGNNNGSC SGSGVVLSQT  960
MLVCCTGDNH DGPRKLSGEY VCTDVSVRDV QEAVEMSDQE FEEPRSIVTN IEDEQSSQMV  1020
QPTTREAVSG DHTQVEGAEA VCTRENLCSE NILHTDHSSA QVGMEVPETN MASEDIVVDI  1080
SLDAEPLGSS DILCSSNGDQ ASSNELQVPD DELTMESEVS SSENKEVIKT PNSMGEAKKK  1140
WKIESESEAN DNPETKNGFI KSPCEGLRSR GKRKAICETS SNLTETSDEE KKLTAKRLKK  1200
TPKARSGSHH QQEISTTTDH HRCYLEGCKM TFETKAKLQT HKRNRCTHEG CGKKFRAHKY  1260
LVHHQRVHND DRPFACSWKG CSKAFKWQWA RTEHLRLHTG ERPYVCKIEE CGLSFRFVSD  1320
YSRHRRKTGH YVT
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ip0_A4e-56246446137346Transcription factor jumonji (Jmj) family protein
6ip4_A4e-56246446137346Arabidopsis JMJ13
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1808822RRKEEKIIQYSRKKK
Functional Description ? help Back to Top
Source Description
UniProtActs probably as a histone 'Lys-4' (H3K4me) demethylase. Involved in transcriptional gene regulation. Acts as a repressor of the photoperiodic flowering pathway and of FT. Binds around the transcription start site of the FT locus. {ECO:0000269|PubMed:15377760, ECO:0000269|PubMed:18467490, ECO:0000269|PubMed:19946624}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK24872.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY6645000.0AY664500.1 Arabidopsis thaliana early flowering 6 (ELF6) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010490928.10.0PREDICTED: probable lysine-specific demethylase ELF6
SwissprotQ6BDA00.0ELF6_ARATH; Probable lysine-specific demethylase ELF6
TrEMBLA0A087G4S00.0A0A087G4S0_ARAAL; Putative lysine-specific demethylase elf6-like
STRINGA0A087G4S00.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM115202731
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G04240.10.0C2H2 family protein
Publications ? help Back to Top
  1. Heidari B,Nemie-Feyissa D,Kangasjärvi S,Lillo C
    Antagonistic regulation of flowering time through distinct regulatory subunits of protein phosphatase 2A.
    PLoS ONE, 2013. 8(7): p. e67987
    [PMID:23976921]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Crevillén P, et al.
    Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state.
    Nature, 2014. 515(7528): p. 587-90
    [PMID:25219852]
  4. Yang H,Howard M,Dean C
    Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(33): p. 9369-74
    [PMID:27482092]