PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

bZIP

Protein Properties

Length: 294aa MW: 31804.4 Da PI: 5.9508

Description

bZIP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00152.6	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	bZIP_1	28.1	4.5e-09	103	150	4	51
XCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH CS bZIP_1 4 lkrerrkqkNReAArrsRqRKkaeieeLeekvkeLeaeNkaLkkelee 51 ++ +r N+eA r++R++Kka+ + Le++v L a N++L k+l+ evm_27.model.AmTr_v1.0_scaffold00152.6 103 QQKKKRPLGNKEAVRKYREKKKARAASLEDEVVHLRAMNHQLMKKLQG 150 578899999***********************************9984 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.20.5.170	9.3E-14	98	168	No hit	No description
SMART	SM00338	2.2E-9	100	167	IPR004827	Basic-leucine zipper domain
PROSITE profile	PS50217	8.956	102	149	IPR004827	Basic-leucine zipper domain
Pfam	PF07716	1.4E-12	102	157	IPR004827	Basic-leucine zipper domain
CDD	cd14686	2.08E-12	105	159	No hit	No description
SuperFamily	SSF57959	6.13E-7	105	150	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0071294	Biological Process	cellular response to zinc ion
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 294 aa Download sequence Send to blast
MEDGEIDFSN QDVFSRPSME MGLGDCDDGC SMGSFFEDLF VKDIHSQSCT HTHTCNPPAG 60 PDLAHTHTCF HVHTKILSSA DPNNDDDAAA TTGEEESSSI NEQQKKKRPL GNKEAVRKYR 120 EKKKARAASL EDEVVHLRAM NHQLMKKLQG QAALEAEVAR LKCLLVDIRG RIEGEIGSFP 180 YTNKPPPSSS VLQHQQPLTG GGFALNSCNL EQCDNEQLQC FRPSDKSVQE DVPLHNNGGL 240 SQGFGVCDVP AVQCGNPLIV GSSKEVGGCA YGNPLPAVVP STSRRRRTRG TDG*

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the response to zinc ion deficiency. Binds to the consensus sequence 5'-[AG]TGTCGACA[CT]-3' also called zinc deficiency response element (ZDRE). The ZDRE sequence is conserved in the plant kingdom and present in the promoters of genes that constitute the primary response to zinc deficiency, comprising additional ZIP metal transporter genes (PubMed:20479230, PubMed:26306426). Required for zinc accumulation in roots. Mediates the expression of the zinc transporters ZIP3, ZIP4, ZIP5 and ZIP9 during growth in zinc-deficient conditions. ZIP9 transporter is involved in zinc uptake in roots (PubMed:26306426). {ECO:0000269\|PubMed:20479230, ECO:0000269\|PubMed:26306426}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by zinc deficiency. {ECO:0000269\|PubMed:20479230}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006846902.1	0.0	basic leucine zipper 19
Swissprot	Q8VY76	4e-69	BZP19_ARATH; Basic leucine zipper 19
TrEMBL	W1PKC1	0.0	W1PKC1_AMBTC; Uncharacterized protein
STRING	ERN08483	0.0	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP1970	15	36

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G35040.1	3e-55	bZIP family protein

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00152.6
Entrez Gene	18436615

Publications ? help Back to Top
Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Azevedo H, et al. Transcriptomic profiling of Arabidopsis gene expression in response to varying micronutrient zinc supply. Genom Data, 2016. 7: p. 256-8 [PMID:26981422] Castro PH, et al. Phylogenetic analysis of F-bZIP transcription factors indicates conservation of the zinc deficiency response across land plants. Sci Rep, 2017. 7(1): p. 3806 [PMID:28630437] Henriques AR,Farias DDR,Costa de Oliveira A Identification and characterization of the bZIP transcription factor involved in zinc homeostasis in cereals. Genet. Mol. Res., 2017. [PMID:28671251] Nazri AZ,Griffin JHC,Peaston KA,Alexander-Webber DGA,Williams LE F-group bZIPs in barley-a role in Zn deficiency. Plant Cell Environ., 2017. 40(11): p. 2754-2770 [PMID:28763829] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]