PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; basal Magnoliophyta; Amborellales; Amborellaceae; Amborella

Family

MYB_related

Protein Properties

Length: 331aa MW: 36191.4 Da PI: 10.1346

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
evm_27.model.AmTr_v1.0_scaffold00007.163	genome	TAGP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	34	6.6e-11	35	85	1	46
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHT.....TTS-HHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmg.....kgRtlkqcksrwqk 46 +++WT eE+ l +v ++G+g W+tI + R+ ++k++w++ evm_27.model.AmTr_v1.0_scaffold00007.163 35 KQKWTSEEEAALRAGVDKYGPGKWRTILKDPVfsvilALRSNVDLKDKWRN 85 79*********************************88*********9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	10.792	30	91	IPR017930	Myb domain
SuperFamily	SSF46689	1.08E-15	32	107	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.1E-13	33	86	IPR009057	Homeodomain-like
SMART	SM00717	7.3E-6	34	89	IPR001005	SANT/Myb domain
Pfam	PF00249	1.3E-7	35	85	IPR001005	SANT/Myb domain
CDD	cd11660	3.80E-18	36	86	No hit	No description
SuperFamily	SSF46785	2.88E-16	149	222	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM00526	1.3E-15	149	214	IPR005818	Linker histone H1/H5, domain H15
PROSITE profile	PS51504	23.555	151	219	IPR005818	Linker histone H1/H5, domain H15
Gene3D	G3DSA:1.10.10.10	2.6E-15	154	216	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF00538	3.1E-9	156	212	IPR005818	Linker histone H1/H5, domain H15
CDD	cd00073	9.79E-11	157	212	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006334	Biological Process	nucleosome assembly
GO:0006357	Biological Process	regulation of transcription from RNA polymerase II promoter
GO:0009651	Biological Process	response to salt stress
GO:0009723	Biological Process	response to ethylene
GO:0009733	Biological Process	response to auxin
GO:0009737	Biological Process	response to abscisic acid
GO:0009739	Biological Process	response to gibberellin
GO:0009751	Biological Process	response to salicylic acid
GO:0009753	Biological Process	response to jasmonic acid
GO:0046686	Biological Process	response to cadmium ion
GO:0000786	Cellular Component	nucleosome
GO:0005730	Cellular Component	nucleolus
GO:0003691	Molecular Function	double-stranded telomeric DNA binding
GO:0033613	Molecular Function	activating transcription factor binding
GO:0042803	Molecular Function	protein homodimerization activity
GO:0070491	Molecular Function	repressing transcription factor binding
GO:1990841	Molecular Function	promoter-specific chromatin binding

Sequence ? help Back to Top
Protein Sequence Length: 331 aa Download sequence Send to blast
MEERIESSSR HTEVKSGGPD SLKKVAGFLS MGAPKQKWTS EEEAALRAGV DKYGPGKWRT 60 ILKDPVFSVI LALRSNVDLK DKWRNMSVTA NGWGSREKAR LALKKSQHFS KHDDNPLALS 120 TVVNGIDDEI VDAKPLAMSN GHLQITGPKR TISRLDNLVM DAIANLKEPG GSNKSAIAVY 180 IEDQYWAPPN FKRLLSAKLK TLTASGKLVK IKRKYLIPPN RMLVEERNSG VLLLEGKPRD 240 SPRSERSDVR LLTRSQIDAE LAKMRNMSAQ EAARVAAQAV AEAEVAMAEA EEAAREAEAA 300 EADAEAAQAF AEAAMMTLKS RNSSKLAYKP *

Functional Description ? help Back to Top
Source	Description
UniProt	Binds preferentially double-stranded telomeric repeats. {ECO:0000269\|PubMed:19102728}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00607	ChIP-seq	Transfer from AT1G49950	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011623052.1	0.0	telomere repeat-binding factor 1 isoform X1
Swissprot	Q8VWK4	1e-90	TRB1_ARATH; Telomere repeat-binding factor 1
TrEMBL	W1P659	0.0	W1P659_AMBTC; Uncharacterized protein
STRING	ERN05352	0.0	(Amborella trichopoda)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Representative plant	OGRP855	16	59

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G49950.3	9e-92	telomere repeat binding factor 1

Link Out ? help Back to Top
Phytozome	evm_27.model.AmTr_v1.0_scaffold00007.163

Publications ? help Back to Top
Alexandrov NN, et al. Features of Arabidopsis genes and genome discovered using full-length cDNAs. Plant Mol. Biol., 2006. 60(1): p. 69-85 [PMID:16463100] Amborella Genome Project The Amborella genome and the evolution of flowering plants. Science, 2013. 342(6165): p. 1241089 [PMID:24357323] Schrumpfová PP, et al. Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase. Plant J., 2014. 77(5): p. 770-81 [PMID:24397874] Liang SC, et al. Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet., 2015. 11(12): p. e1005660 [PMID:26642436] Fulcher N,Riha K Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana. Front Genet, 2015. 6: p. 349 [PMID:26779251] Kotliński M, et al. Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain. Plant Physiol., 2017. 174(1): p. 27-34 [PMID:28298478]