PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_7620_iso_3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family bHLH
Protein Properties Length: 322aa    MW: 34446.1 Da    PI: 5.8111
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_7620_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH50.83.1e-16141187455
                                          HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
                                  HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                                           hn  E+rRR+riN+++  L+ l+P++      K +Ka++L +A+eY+k+Lq
  cra_locus_7620_iso_3_len_1404_ver_3 141 VHNLSEKRRRSRINEKLKALQNLIPNS-----NKTDKASMLDEAIEYLKQLQ 187
                                          6*************************7.....5******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000831.08E-18131191No hitNo description
SuperFamilySSF474592.09E-20134197IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.107.3E-20134197IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088817.841137186IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000108.4E-14141187IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003537.6E-18143192IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 322 aa     Download sequence    Send to blast
MSDLYGTDDH SSFEPQSEPV PEPEDMSVFL HNLLQSSPAT AAGGCSAGQS VMMLDYRNSG  60
SMIHSSSAAS LNFSDPGGFF GREAKERVDK TFSSIAGGDC DAVTSSMKRG EGSNANKGSD  120
TSDSAVPGQP RSSKRSRSAE VHNLSEKRRR SRINEKLKAL QNLIPNSNKT DKASMLDEAI  180
EYLKQLQLQV QMLTMRNGFS LHPNYVPGCL PPIQLPAEFD EANVLPNTSR GADIVSGNQE  240
VVMQNVLGTN NSKGSNHQLL LPSITINSNS GSSFALESSF PSHYGLLNHL ASAKDICRDD  300
TLSHLPLDMS CSGNNSSSGV SS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that plays a role in floral organogenesis. Promotes the growth of carpel margins and of pollen tract tissues derived from them. {ECO:0000269|PubMed:10225997, ECO:0000269|Ref.8}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by the A class gene AP2 in the first whorl and by ARF3/ETT in gynoecium. {ECO:0000269|PubMed:11245574}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027090123.11e-132transcription factor SPATULA-like
SwissprotQ9FUA44e-39SPT_ARATH; Transcription factor SPATULA
TrEMBLA0A068U1261e-130A0A068U126_COFCA; Uncharacterized protein
STRINGSolyc04g078690.2.11e-83(Solanum lycopersicum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA75432328
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Pabón-Mora N,Wong GK,Ambrose BA
    Evolution of fruit development genes in flowering plants.
    Front Plant Sci, 2014. 5: p. 300
    [PMID:25018763]
  3. Moubayidin L,Ostergaard L
    Dynamic control of auxin distribution imposes a bilateral-to-radial symmetry switch during gynoecium development.
    Curr. Biol., 2014. 24(22): p. 2743-8
    [PMID:25455035]
  4. Pfannebecker KC,Lange M,Rupp O,Becker A
    Seed Plant-Specific Gene Lineages Involved in Carpel Development.
    Mol. Biol. Evol., 2017. 34(4): p. 925-942
    [PMID:28087776]
  5. Zumajo-Cardona C,Ambrose BA,Pabón-Mora N
    Evolution of the SPATULA/ALCATRAZ gene lineage and expression analyses in the basal eudicot, Bocconia frutescens L. (Papaveraceae).
    Evodevo, 2017. 8: p. 5
    [PMID:28331573]
  6. Reyes-Olalde JI, et al.
    The bHLH transcription factor SPATULA enables cytokinin signaling, and both activate auxin biosynthesis and transport genes at the medial domain of the gynoecium.
    PLoS Genet., 2017. 13(4): p. e1006726
    [PMID:28388635]
  7. Wu M, et al.
    SPATULA regulates floral transition and photomorphogenesis in a PHYTOCHROME B-dependent manner in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2018. 503(4): p. 2380-2385
    [PMID:29966653]